Research Grant Application Instructions New York HIV Research Centers Consortium Grants

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1 The Fundatin fr AIDS Research (amfar) Grants Administratin 120 Wall Street, 13 th Flr New Yrk, NY U.S.A. Research Grant Applicatin Instructins New Yrk HIV Research Centers Cnsrtium Grants CONTENTS Page Page General Infrmatin 1 Budget Restrictins 6 Wrking with the applicatin frms 1-2 Budget Justificatin 6 Face Sheet 2-4 Resurces and Envirnment 6 General Instructins fr Other Frms 4 Bigraphical Sketch and Other Supprt 6 7 Table f Cntents 4 Research Plan and Literature Cited 7 Key Persnnel and Abstract 4 Addenda 8 Relevance Statement 4 Submitting Grant Applicatins 8 9 Leverage Statement 4 Plicies and Cnditins 9 10 Budget 4 6 Applicatin Deadline February 19, 2010, 5:00 p.m. EST Funding decisins t be annunced late March 2010 Perfrmance Perid The anticipated perfrmance perid is 12 mnths starting April 1, 2010 Available Funding Funding is subject t availability and will supprt: Direct csts: $33,000, f which n mre than 10% can be fr administrative csts. Indirect csts are nt allwed. See pages 4 6 fr mre infrmatin abut allwed csts. Wh May Apply T be eligible fr funding under this request fr prpsals, an applicant rganizatin must be a nnprfit research institutin (e.g., a university, hspital, r research institute) lcated in the State f New Yrk. If requested, the applicant institutin must furnish prf f its nnprfit status prir t the release f grant payments. Applicatins are neither requested nr accepted frm fr-prfit entities r rganizatins nt lcated in the State f New Yrk. Grants are nt awarded t individual investigatrs. Applicant principal investigatrs must be affiliated with (i.e., n the staff r faculty f) an eligible rganizatin. General Applicatin Requirements T be cnsidered cmplete, applicatins must be prepared and submitted n the frms prvided and in cmpliance with these instructins. Incmplete applicatins will nt be accepted r reviewed. N materials will be returned. Instructins and Available Assistance Please refer t these instructins as yu prepare yur applicatin; they prvide step-by-step directins and detailed infrmatin t guide yur cmpletin and submissin f all applicatin cmpnents. If yu have any questins abut the instructins r have difficulty with the frms, please cntact the amfar grants administratin ffice by telephne at r t grants@amfar.rg. Saving and Wrking with the Applicatin Frms If yu are nt using Micrsft Wrd 2003 (r an earlier versin) t prepare yur applicatin, please make sure t save all dcuments as Micrsft Wrd Dcuments saved as Micrsft Wrd 2003 will have the suffix.dc. Page 1 f 10

2 Naming the Applicatin Frms It is very imprtant that the electrnic cpy yu send is named crrectly. Carefully fllw these instructins. When the frms are ready fr submissin, and befre yu print r the final cpy: 1. Under the file menu, select save as. 2. Save yur dcument using the principal investigatr s last name fllwed by -NYS-48. The file name shuld be similar t this: Smith-NYS-48.dc 3. Clse and then re-pen the dcument. Yu shuld nw see the file name in the header at the tp f each page. (Page numbers shuld display in the fter.) NB: If the file name des nt appear in the header, there is n cause fr alarm: in mst cases, this prblem rectifies itself when the ed dcument is pened by the amfar grants administratr; if this des nt happen, we will make sure that all pages are prperly identified. Please cntact the amfar grants administratin ffice (grants@amfar.rg) if yu have any questins. 4. The face page, signed by the principal investigatr and institutin fficial shuld be scanned and saved as a PDF with a file name in the fllwing frmat: smith-facepage.pdf. 5. See page 8 fr infrmatin abut the preparatin and naming f the face sheet, bigraphical sketches, research plan and addenda. Face Sheet In all sectins f the applicatin, please d nt enter infrmatin in any area that is shaded gray. Frm sectins 1-4 are prtected fr data cllectin. Yu may enter infrmatin nly in areas where yu are able t place yur cursr. Identificatin Number Leave this sectin blank. Research Tpic Area Respnse is required. Use the drpdwn t enter the type f research prpsed in this applicatin. Fr Sectins 1-4, please refer t these general instructins. The tw-letter state abbreviatin (NY) is pre-entered. Enter the 5 r 9 (5+4) digit zip cde. Only dctral-level degrees (e.g., Ph.D., M.D., D.Sc.) shuld be entered. Enter prfessinal psitin title (e.g., Prfessr, Senir Scientist, Instructr, Pst-dctral Researcher) at institutin. Signature f bth principal investigatr and institutin fficial are required and attest t the accuracy and cmpleteness f all infrmatin included in the applicatin. A PDF f the signed face page is t be submitted alng with the applicatin frms and research plan; hard cpies bearing riginal signatures will be required frm applicants whse prpsals are apprved fr funding. D nt cpy and paste infrmatin frm these sectins int ther sectins f the applicatin. Page 2 f 10

3 Sectin 1: Applicatin and Institutin Infrmatin Title f prject Titles may nt exceed 75 characters including spaces. D nt use title case r all capital letters. Applicant Institutin: Please enter the cmplete legal name and principal lcatin (street address, city, state, zip cde) f the nnprfit institutin r rganizatin t which a grant wuld be made. Emplyer Identificatin Number (EIN) and nnprfit status Under this RFP, grants will be awarded nly t U.S. tax-exempt charities and nnprfit institutins. The federal EIN must be prvided by all applicants. Organizatins that have been determined by the IRS t be a 501(c)(3) shuld check the crrespnding bx. (If the applicant institutin is a supprting rganizatin, r private fundatin, please identify type in the Other field at the right.) Other nnprfit rganizatins are t succinctly specify the type f rganizatin in the bx next t Other. All applicants shuld be prepared t furnish dcumentatin f U.S. tax-exempt nnprfit status. Human Subjects, Animal Subjects and Hazardus Materials Fr prjects invlving any f the abve, evidence f institutinal apprval must be prvided befre a grant may be activated fr payments. (See page 12 fr mre infrmatin.) Fr each area, nte the status f apprval by checking the bx t the right f the apprpriate descriptin; if apprvals are pending, please prvide supprting dcumentatin (e.g., cpy f cver mem t IRB) in the addenda; if an area des nt apply, check the bx t the right f NA. Perid f Perfrmance Perids f perfrmance fr grants must start April 1, 2010 with an end date f March 31, Upn award f a grant, the New Yrk HIV Research Centers (Cnsrtium) and/r amfar may, at their discretin, designate a perid f perfrmance different than that indicated in these instructins. This sectin is pre-set. Csts Enter ttal csts requested. See pages 4 6 fr discussin f allwed csts. This amunts and the amunt shwn n the budget page must be the same. D nt cut and paste frm this page int the budget page. Sectin 2: Principal Investigatr Only ne principal investigatr may be indicated n a grant applicatin. C-investigatrs shuld be listed as such in the key persnnel list n the peer language abstract page, and bigraphical infrmatin prvided as directed. Sectin 3: Institutin Officer This sectin must be cmpleted by all applicants and prvide the requested infrmatin fr the institutin fficer r ther individual wh, being duly authrized by the institutin, has apprved submissin f the applicatin. Sectin 4: Payment Infrmatin Please make sure the first bx in this sectin crrectly identifies t whm payments shuld be made (i.e., the pay t the rder f Page 3 f 10

4 name fr checks). This must be the legal name (r a legal ding business as (D.B.A). name) f the applicant institutin listed n the face sheet. The individual identified in this sectin shuld be the persn t whse attentin payments wuld be sent. In n instance will grants be paid t individuals r fr-prfit entities. General Instructins fr Other Frms 1. D nt cpy and paste infrmatin frm the face page and payment infrmatin sectins int ther sectins f the applicatin. 2. D nt change the margins fr any f the applicatin frms r sectins. 3. D nt enter any infrmatin r make any changes t grey shaded areas (bxes) n the frms. 4. D nt change fnts r fnt sizes. Fr each area where infrmatin is t be entered, the fnt and size are preset fr cnfrmance t frmatting requirements. All sectins must be cmpleted using Times New Rman. 5. D nt cndense character r line spacing. 6. Applicatins must cnfrm t all page and wrd maximums and frmatting requirements (which are strictly bserved) t be accepted fr review. Table f Cntents Cmplete this sectin after having prepared the entire applicatin. Enter the start page fr each item in the table f cntents; the first eight pages are already numbered because they will be the same fr every applicatin. Addenda (see page 8): In the far right clumn, enter the page numbers fr all addenda materials included with the applicatin. Key Persnnel and Abstract Place yur cursr in the first empty table cell at the tp f this frm and type the prject title. (D nt cut and paste frm the face page.) Next, under the crrespnding clumn headings, enter the name, prfessinal title (e.g., Scientist, Prfessr) and department/institutin fr each f the key persnnel t be engaged n the prject. List the principal investigatr first. If yu need additinal lines fr persnnel, use the tab key frm the lwer right-hand cell t create a new rw belw. Please d nt delete any f the rws r change the fnt size/style frm the pre-set settings. Underneath (NOT IN) the gray shaded area, prvide a peer-language abstract f 200 wrds r less (12-pint Times New Rman) describing the ratinale, lng-term bjectives, specific aims, and methdlgy f yur prject, and its relevance t the HIV/AIDS epidemic in New Yrk State. The abstract is meant t serve as a succinct and accurate descriptin f the prpsed wrk when separated frm the applicatin. It is nt cnsidered by the Cnsrtium r amfar t be cnfidential infrmatin and may be used in press releases r ther dcuments made publicly available. Submissin f an applicatin is deemed acceptance f this prvisin. Please underline ten (10) key wrds, r phrases. Relevance Statement In 200 wrds r less (12-pint Times New Rman), discuss the direct relevance f the prpsal t the HIV/AIDS epidemic in New Yrk State. The RFP is psted at r may be btained by ing a request t grants@amfar.rg. Leverage Statement Underneath the gray bx, describe ptential funding surces and mechanisms that will be pursuedjusing the data gathered thrugh the prpsed research. One page maximum, use 12 pint Times New Rman. Budget The budget must be submitted n the frm prvided. Infrmatin is t be entered nly in nn-shaded areas. Budgets shuld reflect amunts requested fr the entire perfrmance perid. Please use whle dllars nly (e.g., $ nt $155.80). Page 4 f 10

5 Sectin I: Persnnel Grants: Prvide infrmatin fr all institutin persnnel t be supprted with grant funds. Include all key persnnel emplyed by the applicant institutin, whether persnnel csts are t be supprted with grant funds r nt. (Infrmatin abut key persnnel nt emplyed by the applicant institutin shuld be prvided in sectin 2.) Starting with the principal investigatr, prvide the name, psitin title and percent effrt t be allcated t the prject. The percent effrt shuld reflect the prtin f the whle year that the emplyee is expected t wrk n the prject. Fr example, an emplyee wrking half time fr six mnths wuld be shwn as 25%. Fr each persn, enter the amunts fr salary and fringe benefits t be supprted by the grant in the applicable clumns. Enter the sum f salary and fringe benefits fr each persn in the far right-hand clumn. Enter the subttals fr salary and fringe benefits n the subttals line, and the ttal requested persnnel csts in the bx t the right f persnnel ttal. The budget fr persnnel shuld include any cst-f-living r merit increases that, by applicant institutin plicy, are expected t ccur during the perfrmance perid. Requests fr salary csts fr individuals already emplyed full-time by the applicant rganizatin will be carefully scrutinized fr apprpriateness and need. Salary and fringe benefits paid in whle r in part with funds frm this grant must nt vary frm thse paid t ther emplyees f the institutin, regardless f the surce f funds. General Instructins fr Budget Sectins 2, 4, 5 and 6 In these sectins yu will enter the subttal fr each categry in the bxes n the right-hand side f the table. Detail fr each sectin is t be entered in the bxes in the center clumn, as shwn in the fllwing example. Sectin 2: Cnsultants / Subcntractrs Cnsultants and subcntractrs are nt emplyees f the grantee institutin, nr are they emplyees r cntractrs f the Cnsrtium r amfar. Key persnnel wh are emplyed by ther institutins, including thse wh are cntributing t the prject at n cst, shuld be included in this sectin. Cnsultatin with institutin faculty, staff r ther emplyees shuld be reimbursed by charging an apprpriate prtin f that individual s salary and fringe t the grant as a persnnel item (see abve). Cnsultants are expert r highly specialized and/r technical persnnel whse fr-hire services are urgently, temprarily, and infrequently needed. Cntractrs are hired t prvide specialized scientific r technical persnnel, r services that are identified as essential t the cmpletin f the prject. In the detail sectin (center clumn), list the name and subttal fr each cnsultant/cntractr. Enter the ttal fr cnsultants and subcntracts in the right hand clumn. In the justificatin, prvide the name, functin, number f days f cnsultatin r units r service t be prvided, and the applicable rate. A letter f cmmitment frm each cnsultant r cntractr, stating the scpe f wrk and estimated csts must be included in the addenda. Sectin 3: Supplies and Materials This categry is t be used fr supplies and materials necessary t perfrm the prpsed research. Sectin 4: Equipment Equipment purchase, rental, and maintenance csts are allwable nly fr special-purpse equipment required t perfrm the specific prject and nt therwise available at the applicant institutin. Purchase, rental and maintenance f ffice equipment, including persnal cmputers, laptp cmputers, furniture and similar general-purpse items are generally nt allwed fr funding. Equipment must be itemized in the center clumn and cmplete details prvided in the budget justificatin. Page 5 f 10

6 Sectin 5: Administrative Csts Up t 10% f the ttal amunt requested may be applied t specific administrative csts. The justificatin must detail the specific csts t be supprted. Include such items as institutin fees fr use f special equipment and ccupancy csts. Requests t supprt ccupancy csts (i.e., rent) shuld be included nly if implementatin f the prject requires renting facilities nt currently available t the institutin, r if the institutin charges user fees fr specialized facilities n a prject-by-prject basis regardless f surce f supprt. The supprt f administrative csts is subject t apprval by the Cnsrtium. Sectin 6: Other Direct Csts Use this sectin fr csts that d nt fall in the categries described abve. Ttal Direct Csts Enter the ttal direct csts as shwn in the example t the right. In n case are ttal direct csts t be greater than $33,000. Under this RFP, an indirect cst rate is nt allwed. Budget Restrictins Funds are nt awarded fr the fllwing: Majr cnstructin r the remdeling f facilities (minr alteratins are allwed with adequate justificatin) The direct cst f supprt services and facilities generally available at a spnsring institutin (ccupancy csts, utilities, maintenance, telephne, ffice furniture and supplies, etc.) except when directly allcable and essential t carrying ut the prpsed research Indirect csts The purchase, lease r rental f ffice equipment Funding fr dissertatin research Travel csts (ther than lcal travel necessary t cnduct the research, e.g., t cnduct interviews) Grants awarded under this RFP are nt meant t cver the ttal cst f a prpsed research prject. A grantee institutin is expected t prvide the necessary physical facilities and administrative services as well as ther supprting services nrmally available at a spnsring institutin. Budget Justificatin A cmplete budget justificatin, n the frm prvided, is required. Applicatins received withut the required budget justificatin will nt be accepted fr review. Resurces and Envirnment Briefly describe the facilities t be used at the applicant rganizatin, their nature, pertinent capabilities, and relative prximity and extent f availability t the prject. Use Other t describe facilities at ther perfrmance and field study sites available t the prject. If a significant prtin f the prpsed research activity will be cnducted at a lcatin ther than the applicant institutin, prvide a separate resurces and envirnment frm fr each site. Please cntact the amfar grants administratin ffice fr assistance with making duplicates f this frm (grants@amfar.rg). Belw the table, using cntinuatin pages if necessary, describe applicable cnsrtium agreements with ther rganizatins. Shuld a cnsrtium agreement exist, a cpy shuld be included in the addenda, alng with agreements frm cllabratrs, cnsultants and cntractrs. Place yur cursr in the cells t the right t each f the categries t enter relevant infrmatin. Bigraphical Sketches and Other Supprt Frm(s) Bigraphical sketch and ther supprt frms must be cmpleted fr the principal investigatr and fr each f the key prfessinal persnnel listed n page three f the applicatin. These frms shuld nt be cmpleted fr labratry technicians, administrative supprt staff r the like. Bigraphical Sketches Submit an NIH bigraphical sketch (e.g., PHS: 398/2590 Bigraphical sketch frmat page), mitting the ther supprt sectin, fr each f the key persnnel. These frms shuld be submitted as ne PDF file separate frm the ther applicatin cmpnents. Frmat the file name as fllws: PI last name-bi.pdf, e.g., smith-bi.pdf ). Bigraphical sketches will be inserted int the applicatin by amfar grants administratin staff befre distributin t reviewers. Page 6 f 10

7 Other Supprt An Other Supprt Frm shuld be prvided fr each f the key persnnel and in the same rder as the bigraphical sketches, which are t be submitted separately as described abve. Detailed instructins are at the tp f the frm. Enter requested infrmatin in the space beneath the crrespnding gray shaded sectin headers. Cnsrtium funds cannt be used t duplicate supprt prvided by anther rganizatin. Hwever, supprt frm the Cnsrtium can be used t supplement supprt frm ther surces (i.e., supprt fr related prjects whse aims and/r methdlgies are clearly distinct and severable frm the prpsed research). Accrdingly, a prject s principal investigatr and the applicant institutin must diligently insure that all infrmatin presented in an applicatin, including ther supprt, is accurate and inclusive. Failure t d s may be cnstrued as an attempt t mislead the Cnsrtium and/r amfar and will lead t the rejectin f an applicatin, r terminatin f a grant and the required return f all funds received. Requests fr supprt f this nature are carefully scrutinized fr apprpriateness. Research Plan & Literature Cited The research plan is t be submitted by as a separate dcument and shuld: state the hyptheses and the prject s specific aims cncisely describe the backgrund and ratinale fr the prject and the gap in knwledge it is intended t fill relate specific aims t lng-term bjectives summarize the principal investigatr s preliminary studies clearly and cncisely describe the experimental design and the prcedures t be used prvide a timetable fr the prject s executin discuss the means by which the data will be analyzed and interpreted pint ut new methdlgies, if any, and their advantages ver existing nes Literature cited shuld immediately fllw the research plan and shuld nt be included in the research plan wrd cunt. RESEARCH PLAN FORMATTING REQUIREMENTS AND PAGE LIMITS Applicatins cntaining research plans that d nt cnfrm t these requirements, which are strictly enfrced, will nt be accepted fr review. Research plans must be written in English N mre than 1,200 wrds in length Duble-spaced 12-pint Times New Rman; d nt cndense character r line spacing 1 inch margins r 2.55 cm (tp, bttm, left, right) Page Size: U.S. letter (8½ x 11 inches). This frmatting is required fr the ed versin. Figures and/r tables are limited t ne page, which shuld immediately fllw the literature cited; figures shuld nt be embedded in the research plan itself. Figure legends are t be in 12 pint Times New Rman. The research plan is t be prepared and submitted in a separate wrd prcessing dcument. Open a new dcument, set paper size fr U.S. letter (8.5 x 11 ), set all margins at ne inch, select duble-spacing and 12-pint Times New Rman fnt. Type Research Plan r the applicatin title at the tp f the first page, starting the plan prper belw that line. Use a header t identify the dcument by file name in the upper right hand crner. Page numbers shuld be nt be cnsecutive with the frms (i.e., start the plan with page 1 and include the wrd plan in the fter), and shuld be placed in a fter. Save the research plan using the fllwing naming cnventin: PI-last name-plan.dc (e.g., smith-plan.dc) Page 7 f 10

8 Addenda The fllwing items are addenda t the research plan, d nt cunt as part f its 10 pages, and shuld ed alng with the research plan in the rder shwn.) Please insert a page with the wrd addenda centered in large letters between the literature cited and the first item in the addenda. A. Figures and/r Tables Figures and/r tables are limited t ne page; legends are t be in 12 pint Times New Rman. B. Institutinal Apprvals All funded research investigatins are cnducted under the versight and directin f the grantee institutin. Accrdingly, the institutin bears full respnsibility t insure that research facilities, activities (e.g., experiments and prtcls), and emplyees cmply with applicable federal, state, and lcal laws and regulatins. An investigatin invlving either human r animal subjects r derivatives f such subjects, r bihazards may nt initiate research activity r make expenditures until its entire prtcl has been reviewed and apprved in accrdance with applicable regulatins and guidelines including thse established by the U.S. Department f Health and Human Services (DHHS), the U.S. Department f Agriculture (USDA) and the Natinal Institutes f Health (NIH). Human Subjects If human subjects are t be used, dcumentatin f apprval by the institutin s Institutinal Review Bard (IRB) and a cpy f the IRB-apprved patient s infrmed cnsent frm must be submitted. Animal Subjects If animal subjects are t be used, dcumentatin f apprval by the Institutinal Animal Care and Use Cmmittee (IACUC) must be submitted. Bihazards If the investigatin will use r result in the prductin f hazardus materials, dcumentatin f Institutinal Bisafety Cmmittee (IBC) apprval must be submitted. If apprvals are pending, please prvide supprting dcumentatin (e.g., cpy f cver mem t IRB). N payments fr a funded grant will be issued until all necessary apprvals have been received and accepted by amfar. B. Letters f cllabratin frm and letters f agreement and cnsrtium agreements with cntractrs, cnsultants and cllabratrs. Additinal materials shuld nt be submitted and, if included will nt be prvided t reviewers. Submitting Grant Applicatins All applicatin cmpnents must be submitted timely t be accepted fr review. Deadline February 19, 2010, 5:00 PM (Eastern Standard Time) Send cmpnents as attachments t: grantapps@amfar.rg All applicants are required t submit all f the fllwing as attachments: The applicatin frms as a wrd prcessing dcument cmprised f all f cmpnents (except bigraphical sketches, research plan and addenda) as listed in the table f cntents. (file name: PI last name-nys-48.dc; e.g, smith-nys-48.dc ) D nt submit the applicatin frms as a PDF. PDF f the signed applicatin face page (file name: PI last name-facepage.pdf,.e.g., smith-facepage.pdf Bigraphical Sketches in ne PDF. Frmat file name as PI last name-bi.pdf, e.t., smith-bi.pdf The research plan as a separate wrd prcessing dcument. (file name: PI last name-plan.dc; e.g., smithplan.dc D nt submit the research plan as a PDF. The addenda are t be submitted in ne PDF. (file name: PI last name-addenda.pdf; e.g., smith-addenda.pdf) Page 8 f 10

9 Dcuments are t be named in the manner described abve. The subject line f the shuld read: Cnsrtium applicatin Investigatr s Last Name (e.g., Cnsrtium Applicatin Smith). The bdy f the shuld include cntact infrmatin fr the principal investigatr and, if applicable, ne ther persn wh shuld be cntacted if questins arise. Please submit ed applicatins timely. amfar s plicy is t nt accept applicatins that are submitted late. Plicies and Cnditins Descriptins Research grants satisfy varius financial bligatins incurred in the curse f an HIV/AIDS-related investigatin. In general, a research grant is applied t direct csts f salaries fr prfessinal and technical persnnel, labratry supplies and equipment, and ther csts directly related t the research. T Whm Grants Are Made Grants are awarded t nnprfit institutins in the state f New Yrk; they are nt awarded t individual investigatrs. If requested, the applicant institutin must submit prf f its nnprfit status. Applicatins are neither requested nr accepted frm fr-prfit entities. By accepting a Cnsrtium grant, the recipient institutin will affirm the cmpleteness and accuracy f the applicatin submitted fr funding. The institutin will als accept full respnsibility fr the cnduct f the investigatin and fr the acts f the investigatr(s). Bth are under the directin f the institutin and are subject t its medical and scientific plicies. Similarly, prject persnnel cmpensated in full r in part with funds awarded by the Cnsrtium/amfAR are emplyees f the recipient institutin; they are nt Cnsrtium r amfar emplyees. Applicants need nt be U.S. citizens, and there are n restrictins as t age, clr, creed, gender, medical cnditin, handicap, natinal rigin, parental status, plitical affiliatin, race, religin, marital status, r sexual rientatin. Applicants must, hwever, be affiliated with a nnprfit institutin in the state f New Yrk. Members f the Cnsrtium s steering cmmittee r chairs f the fur Cnsrtium research wrk grups are nt eligible as investigatrs in this Cnsrtium-supprted research. Restrictins Funds are nt awarded fr the fllwing: Majr cnstructin r the remdeling f facilities (minr alteratins are allwed with adequate justificatin); The direct cst f supprt services nrmally available at a spnsring institutin (e.g., telephne, ffice furniture, and supplies) except when directly allcable and essential t carrying ut the prpsed research; The purchase, lease, rental, r servicing f ffice equipment; Funding fr dissertatin research; Travel; Indirect csts Cnsrtium grants are nt meant t cver the ttal cst f a prpsed research prject. A grantee institutin is expected t prvide the necessary physical facilities and administrative services, as well as ther supprting services nrmally available at a spnsring institutin. When an applicatin fr prject supprt is submitted t the Cnsrtium/amfAR and als t ther grant making agencies, accepted supprt frm the Cnsrtium and frm anther agency cannt be in duplicatin. Recipient institutins agree nt t prmte r engage in vilence, terrrism, r the destructin f any state, and t take prudent measures t insure that they d nt prvide supprt thrugh sub-grants r ther financing t any entity that engages in thse activities. Surce f Funds Grants disbursed by amfar are apprved by the New Yrk HIV/AIDS Research Centers Cnsrtium. This initiative has been made Page 9 f 10

10 available by the New Yrk State legislature fr the purpse f prmting HIV/AIDS research relevant t the epidemic in New Yrk State. Funding is subject t availability and awarded withut assurance f cntinued r subsequent funding. Review and Apprval Prcess The Cnsrtium intends t encurage and supprt HIV/AIDS research f the highest quality. Therefre, every prperly prepared and submitted applicatin received in respnse t this slicitatin will be peer-reviewed. Each is subject t an verall cnfrmance review by amfar staff. Thse fund t be incnsistent with the guidelines and instructins are eliminated at that time, and the investigatr and the applicant institutin s grants fficial are ntified. Peer reviewers, a vlunteer bdy f scientists wh are experts in varius fields f HIV/AIDS research, evaluate (1) the scientific merit f applicatins; (2) the relevance f the research t the HIV/AIDS epidemic in New Yrk State; (3) the qualificatins, experience, and prductivity f the investigatr/spnsr; (4) the facilities available; and (5) the likelihd f success. The peer reviewers determinatins are cnsidered by the steering cmmittee and research wrking grup chairs f the New Yrk HIV Research Centers Cnsrtium, which hlds the sle authrity t apprve prject funding. Cnfidentiality Thrughut the review and award prcess, amfar respects the privacy f the applicant and endeavrs t prtect frm disclsure any cnfidential r prprietary infrmatin cntained in a submitted prpsal. Hwever, amfar has in place n mechanisms t maintain r guarantee cnfidentiality and, as a nt-fr-prfit crpratin, lacks the financial resurces t (1) institute such mechanisms r (2) accept liability fr the disclsure f infrmatin. At the same time, amfar des nt cnsider infrmatin n an applicatin s abstract t be cnfidential. That infrmatin may be made public as a descriptin f the prject being funded by the Cnsrtium. Submissin f an applicatin is deemed acceptance f these prvisins. Human and Animal Subjects / Bihazards Applicants are required t submit dcumentatin f institutinal apprvals fr research invlving human r animal subjects r the use r prductin f bihazards. Research activity may nt begin, nr may expenditures be made, until such apprvals are received and frwarded t amfar. The Awarding Agency (amfar) reserves the right, upn the advice r directin f the Cnsrtium r the State f New Yrk, t: 1. Reject any and all applicatins received in respnse t this RFP. 2. Award mre than ne cntract resulting frm this RFP. 3. Waive and/r mdify minr irregularities in applicatins received after prir ntificatin t the applicant. 4. Adjust r crrect cst figures with the cncurrence f the applicant if errrs exist and can be dcumented t the satisfactin f amfar. 5. Negtiate with applicants respnding t this RFP within the requirements t serve the best interests f amfar and/r the Cnsrtium. Page 10 f 10

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