Making the case for Horizon Scanning
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1 Making the case for Horizon Scanning Facing the challenges: Equity, Sustainability and Access Aldo Golja, Beneluxa Coordinator Ministry of Health, The Netherlands
2 1 Introduction Samuel Becket bridge, Dublin 2
3 A question to payers How well do we know the impact of Spinraza (nusinersen)? Targeted population Expert opinions Impact on care pathway Expected price & budget-impact Competitors expected to enter the market Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
4 2 Horizon Scanning defined Graslei, Gent (B)
5 Horizon Scanning A HSS aims at identifying, filtering, and prioritising new and emerging health technologies with a considerable predicted impact on health, costs, society and the health care system in order to inform policymakers, purchasers, and health care providers or facilitate early access (KCE report 2017) Performed in some countries e.g. UK, Italy, Denmark, Sweden, Austria and the Netherlands Universal need for predictive data: potential to enhance data collection internationally Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
6 The potential of Horizon Scanning Improvement of Access Prioritisation (policies & capacity planning) Earlier planning for guidelines and registries Efficiency gains streamlining procedures from MA -> Prescription (e.g. early access schemes) Potential for savings Budget planning Creating a level playing field negotiations Early identification enables collaboration Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
7 End-users and how they can use the data Payers & Policy makers Assessment bodies Prescribers Patients Hospitals To inform negotiations To estimate budget impact To allow for early dialogue based on a level playing field To prioritise assessments To plan assessments to ensure minimal waiting time for patients To allow for early dialogue based on a level playing field To accelerate guidelines, appropriate use and registries To inform health services and hospitals of future products and their impact To inform patients on expectations of upcoming developments To adapt policies ensuring access Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
8 Data flow Assessment bodies Hospitals Health insurers HSS Payers Patient organisations National horizon scanning bodies Tender organisations International organisations Specialists Data flow Commissioning groups Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
9 3 International Horizon Scanning Initiative Rotterdam Central Station (NL)
10 International Horizon Scanning Initiative (IHSI) Open to all countries (not limited to Beneluxa) 10+ countries interested (EU + non-eu) Dialogue with International organizations on access to data Solidarity principle: Costs shared based on Purchase Price Parity and population Potential contributions for smaller low-ppp countries as low as External party to build infrastructure Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
11 Data sources Registries of clinical data Regulatory authorities including FDA and EMA Scientific reports and journals Input from clinical experts and industry Investor data and outlooks Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
12 Horizon scanning database Dataset 1 (baselist) Filter Originator pharmaceuticals (Phase II or phase III) / medical technologies grade 2b/3 Biosimilars and generics (first to market only) Special status (e.g. Orphan, ATMP) Dataset 2 (filtered list) Defined variables Dataset 3 (high impact) High impact Dataset 4 Dataset 5 Withdrawn / failed pharmaceuticals Registered pharmaceuticals Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
13 Parameters for high impact Health organization Health care costs Population level Patient level Volume risk Health care use Infrastructure Impact on services delivery Impact on disease management Innovation gain First in class / availability of alternatives Unmet clinical need Patients / clinical demand Patient population Orphan designation Prevalence / incidence of disease Patient oriented impact Therapeutic value Life expectancy Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
14 Limitations The HSS does not prioritise for countries The HSS does not make any decisions on pricing and reimbursement or market entry Data collected is not tailored to specific countries Data collected is factual with the exception of the high impact reports Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
15 National Horizon Scanning in the Netherlands Starting point of discussion with all stakeholders Plays a role in negotiations between health insurance companies and hospitals 71% of hospitals uses the national scan in negotiations with health insurance companies 88% of health insurance companies use the national scan in negotiations with healthcare providers Starting point for the Ministry of Health to decide which drugs are eligible for managed entry agreements Hospitals to use data for faster uptake of biosimilars and generics Data is publicly available Media uses the data for discussion on drug pricing Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
16 Planning Meeting for interested countries December 14, Brussels Tender published March, 2019 Selection of candidate and start of work mid-2019 Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
17 5 Conclusion Waves of the Donau, Vienna
18 Business case Costs Benefits Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
19 If horizons scanning saves 1 and 5% of current expenditure on pharmaceuticals the savings in Europe amount to 2 and 11 billion. Country Total health expenditure ( millions) (OECD 2018) % pharmaceutical spent Pharmaceutical spent ( millions) IHSI saving at 1% ( millions) IHSI saving at 5% ( millions) Austria ,6 12% Belgium ,5 15% Czech Republic 13762,4 17% Denmark 29376,2 7% Estonia 1.545,4 19% Finland ,1 13% France ,0 14% Germany ,0 14% Greece ,2 26% Hungary 8496,7 29% Iceland 1530,7 12% Ireland ,5 13% Italy ,0 18% Latvia 1.683,6 28% Lithuania 2.642,2 27% Luxembourg 3.366,7 9% Netherlands ,6 8% Norway 35238,7 8% Poland 30799,2 21% Portugal ,8 15% Slovak Republic 6.000,0 26% Slovenia 3.450,1 18% Spain ,9 19% Sweden 49008,7 10% Switzerland 72630,7 14% United Kingdom ,2 11% Total , Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
20 Horizon scanning: Spinraza Budget impact in the Netherlands for total population was estimated above 100 million per year Because of horizon scanning in the Netherlands, Spinraza was not allowed to enter the market before negotiations Open system for hospital products Horizon Scanning allowed for joint negotiations with Belgium 1-5% discount on Spinraza would cover NL contribution for Horizon Scanning Facing the challenges: Equity, Sustainability & Access - Lisbon, November 28-29,
21 Contact: For more information go to: Aldo Golja & Eveline Klein Lankhorst Senior Policy Advisors Ministry of Health, Welfare and Sports, the Netherlands
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