TENDER DOCUMENT FOR THE SUPPLY OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SYSTEM

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1 1 BRNS-DAE Project Department of Botany Patna University (Sanctioned order No. 2012/35/5/BRNS dated ) Tender Notice No. BRNS/BP/T/01/ Dated: TENDER DOCUMENT FOR THE SUPPLY OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SYSTEM DATE OF ISSUE OF TENDER DOCUMENT: LAST DATE & TIME FOR SUBMISSION OF TENDER DOCUMENT: up to PM DATE & TIME FOR OPENING OF TENDER DOCUMENT: at PM

2 2 Microbial & Molecular Genetics Lab, Department of Botany PATNA UNIVERSITY, ASHOK RAJPATH PATNA , BIHAR, INDIA BRNS/BP/T/01/ Dated: NOTICE INVITING LIMITED TENDER FOR SUPPLY OF HPLC SYSTEM 1. Principal Investigator, BRNS-DAE Project, Patna invites limited bids for Supply of HPLC system from reputed companies/firms/individuals/societies etc. those are in the business for the five years. Accordingly, sealed tenders are invited latest by at 3.00 PM. 2. The interested Companies/Firms/Agencies may send their bid complete in all respect along with relevant documents to the undersigned duly superscripted Bid for Tender No BRNS/BP/T/01/ before 3.00 pm on 19 th March, The bids received after this deadline shall not be entertained under any circumstances whatsoever. 3. The sealed envelopes are to be deposited in the tender box placed at the office of PI, BRNS-DAE Project, Microbial & Molecular Genetics Lab, Department of Botany PATNA UNIVERSITY, Patna or may be sent through registered/speed post addressed to PI, BRNS-DAE Project, Microbial & Molecular Genetics Lab, Department of Botany, Patna University, Patna Bids will be opened on at hrs in the presence of bidders or their authorized representatives who wish to participate in the bidding process. If the opening date happens to be a closed day/holiday, the tender will be opened on the next working day. 5. Any future clarification(s) and / or corrigendum(s) shall be communicated by the Principal Investigator, BRNS-DAE Project (bprasad.pu@gmail.com). 6. Principal Investigator, BRNS-DAE Project reserves the right to amend or withdraw any of the terms and conditions contained in the Tender Document or to reject any or all tenders without giving any notice or assigning any reason. The decision of the Principal Investigator, BRNS-DAE Project in this regard shall be final. Principal Investigator, BRNS-DAE Project Microbial & Molecular Genetics Lab, Department of Botany Patna University, Patna , India

3 3 GENERAL INSTRUCTIONS TO THE TENDER 1. The tender is Two Bids document. The technical bid should contain all the relevant information and desired enclosures in the prescribed format. The financial bid should contain only commercial. In case, any bidder encloses the financial bid within technical bid, the same shall be rejected summarily. 2. The tender Document can be downloaded from the website of Patna University or P.G. Biotechnology, P.U.( 3. The Tenders should be typewritten or handwritten but there should not be any overwriting or cutting. Correction, if any, shall be made by neatly crossing out, initialing, dating and rewriting. The name and signature of bidder s authorized person should appear on each page of the application. All pages of the tender document shall be numbered and submitted as a package along with forwarding letter on agency s letter head. 4. The Contracts concluded as a result of this Tender Inquiry shall be governed by the Terms & Conditions and other relevant instructions as contained in this Tender Document. 5. The prices/rates quoted should be indicated in words as well as in figures. 6. Bidders are requested to quote their prices on a firm & fixed basis for the entire period of the Contract. Bids of the firms received with prices quoted on variable basis shall be rejected straightaway. 7. Quotations qualified by such vague and indefinite expressions such as subject to prior confirmation, subject to immediate acceptance etc. will be treated as vague offers and rejected accordingly. 8. Bidders are requested to enclose a copy of their valid certificate of PAN No., TAN No, Sale Tax/VAT No./Service Tax No. or any other document as requested by the Institute with their tender. 9. Bidders may note that if the date of tender opening given in this Tender Document is declared to be a gazetted holiday, the tender shall be opened on the next working day at the same timing. In such an event the closing hours for receipt of tenders in Microbial & Molecular Genetics Lab, Department of Botany, Patna University, Patna will stand automatically extended up to hours of the next working day in the Government offices. 10. Late/delayed tenders received in office due to any reason whatsoever will not be accepted under any circumstances. 11. At any time prior to date of submission of tender, Tender Inviting Authority may, for

4 4 any reason, or decision, modify the terms & conditions of the tender document by a corrigendum displayed on the website of or P.G. Biotechnology, P.U.( 12. In order to provide reasonable time to take the amendment into account in preparing their bid, Tender Inviting Authority may or may not, at his discretion, extend the date and time for submission of tenders. 13. Tendering firms are at liberty to be present or authorize a representative to be present at the opening of the tender at the time and date as specified in the Schedule. The name and address of the representative authorized to attend the opening of the tender on behalf of a tendering firm should be indicated in the tender. The representative so deputed should also bring with him a letter of authority from the firm for having been authorized to be present at the time of opening of tender. Only one representative per firm shall be permitted to attend the opening of the tender. The name and address of permanent representative of the firm, if any, should also be indicated in the tender. Representatives of firms who have not submitted the tender or representatives not possessing authority letter from the bidders or outsiders shall not be allowed to attend the tender opening process. 14. DOCUMENTS COMPRISING THE BID: The bids prepared by the bidder shall comprise of (1) The Technical Bid and (2) Financial Bid: TECHNICAL BID: - To qualify in the Technical bid the firm should have the minimum eligibility criteria; the firm in this regard should submit the following documents (a) Duly filled format of Technical Bid as per Annexure 1. (b) Copy of constitution or legal status of the sole proprietorship/ firm/company etc. (c) Financial status: - The annual turnover of the firm should not be less than Rs. 10 Lakhs per annum (Proof should be enclosed). (d) Copy of PAN Card. (e) Copy of Sales tax/vat registration certificate.

5 5 15. FINANCIAL BID: - The financial bid shall contain: (a) Price Bid Form [as per Annexure 2] 16 SUBMISSION OF BIDS (a) 16.1 SEALING AND MARKING OF BIDS: The bidder shall seal the Technical and Financial Bids in separate envelopes and keep them in a bigger sealed envelope. The Technical Bid shall bear the name TECHNICAL BID OF Tender No. BRNS/BP/T/01/ on the envelope, while the Financial Bid shall bear the name FINANCIAL BID of Tender No. BRNS/BP/T/01/ on the envelope for avoiding any mismatch The bigger envelope containing technical and financial bids in separate envelopes shall be: Principal Investigator, BRNS-DAE Project Microbial & Molecular Genetics Lab, Department of Botany Patna University, Patna , India (b) All the envelopes shall bear the Tender name, the tender number and the words DO NOT OPEN BEFORE (due date & time). (c) The envelopes shall indicate the name and address of the bidders to enable the bid to be returned unopened in case it is declared late. (d) Bids shall be delivered in person and shall be dropped in the tender box placed in the office of the Principal Investigator, BRNS-DAE Project, Microbial & Molecular Genetics Lab, Department of Botany Patna University, Patna , India or shall be sent by Registered/Speed Post. The Purchaser shall not be responsible if the bids are delivered elsewhere. (e) Venue of Tender Opening: Tender will be opened in Principal Investigator, BRNS-DAE Project Microbial & Molecular Genetics Lab, Department of Botany, Patna University, Patna , India, at hrs on the due date. If due to administrative reason, the venue/ time of bid opening are changed, it will be displayed prominently on the notice board of the Institute as well as in the office.

6 6 17. BID PRICES: 17.1 The bidder shall give the total composite price inclusive of all levies and taxes (inclusive of VAT). The basic unit price and all other components of the price need to be individually indicated against the goods it proposed to supply under the contract as per price schedule given in Annexure-2. The offer shall be firm in Indian Rupees only. No foreign exchange will be made available by the purchaser Prices indicated on the Price Schedule shall be entered in the following manner: (i) The price of the goods shall be quoted in total (inclusive of all taxes and levies) for each item. (ii) The bidder shall quote only one price for each item and if more than one price is quoted under different options the rate quoted by him in the first option only will be valid and will be taken for evaluation for all the items given in schedule of requirement The prices quoted by the bidder shall remain fixed during the entire period of contract and shall not be subject to variation on any account. A bid submitted with an adjustable price quotation is likely to be treated as non-responsive and rejected The unit price quoted by the bidder shall be in sufficient detail to enable the purchaser to arrive at prices of the items offered DISCOUNT, if any, offered by the bidders shall not be considered unless they are specifically indicated in the price schedule. Bidders desiring to offer discount shall therefore modify their offers, suitably while quoting and shall quote clearly net price taking all such factors like Discount, free supply, etc. into account The price approved by the P.I. for procurement will be inclusive of levies and taxes, packing, forwarding, freight and insurance as mentioned in para 13.1 above. Break up in various heads like Custom duty, Excise duty, Sales Tax, Insurance freight and other taxes paid/payable as per clause 13.2 is for the information of the purchaser and any changes in the taxes shall have no effect on the price during the scheduled delivery period. 18. TECHNICAL EVALUATION: 18.1Purchaser shall evaluate the technical bids to determine whether they are complete, whether required sureties have been furnished, whether the documents have been properly signed and whether the bids are generally in order. 18.2Prior to the financial evaluation, the Purchaser will determine the substantial responsiveness of each bid to the Bid document. For purposes of these clauses, a substantially responsive bid is one, which conforms, to all the terms and conditions of the Bid Documents without material deviations. The Purchaser's determination of bid's

7 responsiveness is to be based on the contents of the bid itself without recourse to extrinsic evidence. 7

8 A bid determined as substantially non-responsive will be rejected by the Purchaser and shall not subsequent to the bid opening be made responsive by the bidder by correction of the nonconformity. 19. FINANCIAL EVALUATIONS AND COMPARISON OF SUBSTANTIALLY TECHNICAL RESPONSIVE BIDS: 19.1 The purchaser shall shortlist those who are eligible and have submitted substantially technical responsive bid for opening of financial bid. Successful Bidders would be called to attend opening of financial bids. The Financial Bids of unsuccessful bidders would not be opened and destroyed Arithmetical errors shall be rectified on the following basis. If there is a discrepancy between the unit price and total price that is obtained by multiplying the unit price and quantity, the unit price shall prevail and the total price shall be corrected by the Purchaser. If there is a discrepancy between words and figures, the amount in words shall prevail. If the Supplier does not accept the correction of the errors, his bid shall be rejected The evaluation and comparison of responsive bids shall be done on the price of the goods offered inclusive of Levies & Taxes i.e., Sales Tax, VAT & Excise Duty, packing, forwarding, freight and insurance etc. as indicated in the Price Schedule in annexure- 2 of the Bid Document but exclusive of octroi/ entry tax which will be paid extra as per actual, wherever applicable The Purchaser may waive any minor infirmity or non-conformity or irregularity in a bid which does not constitute a material deviation, provided such waiver does not prejudice or affect the relative ranking of any bidder. 20. AWARD OF CONTRACT: PLACEMENT OF ORDER The Purchaser shall consider placement of orders for commercial supplies on those bidders whose offers have been found technically, commercially and financially acceptable and whose goods type have been approved/ validated by the purchaser. The Purchaser reserves the right to counter offer price(s) against price(s) quoted by any bidder.

9 9 TERMS & CONDITIONS OF THE CONTRACT 1. The bidders are expected to read carefully all the terms and conditions of the tender document and their submission will be taken as consent to abide. If the bidder gives deliberately wrong information to create conditions for acceptance of the tender, Principal Investigator, BRNS-DAE Project reserves the right to reject such tenders without assigning any reason. Not more than one tender will be submitted by the bidder for the same work. Legal action will be taken for furnishing wrong information. Manner of Submission of Tender: The bidding should be done on two bid method viz 1) Technical Bid & 2) Commercial / Price Bid. The bidders should ensure that the Technical bid complete in all respect and containing the required enclosures (attested Photocopy) is sealed in a separate envelop and the commercial bid sealed in a separate envelop & both the sealed envelopes are kept and sealed in a suitable size of envelop. All envelop will be address to Principal Investigator, BRNS-DAE Project Microbial & Molecular Genetics Lab, Department of Botany, Patna University, Patna , India 2.. The Sealed Technical bid Envelop of all bidders will be opened first. Only the Commercial bids of those who have furnished all the valid documents will be opened. 3. Language: The language of the Tender shall be in English. 4. Documents to Accompany Tender: The Tenderer shall submit the Documents mentioned in the clause 16 of General Instructions to the Tender. 5. The bidders must have at least 05 (Five) years experiences in this job and credentials of Rs. 10 Lacks annually in this business in the last three years done in any Govt. Organisation directly. Credential Certificate in this regard must be furnished by the bidders along with their Tender. 6. The firm / agency must have requisite trade and other licenses to do the business of Furniture for which the bid is being made.

10 Submission of Documents:- a) Each Tender must accompany attested photocopy of Pan Card, Trade License, Sales Tax Clearance Certificate / VAT Registration Certificate, Service Tax Registration Certificate, and Experience Certificate. b) The bidder must submit attested photocopy of Income Tax, Sales Tax / VAT and Service Tax return of last three years. c) In case of SSI unit, current SSI certificate must be deposited by the bidder along with his Tender which is issued in favour of the bidder for this type of jobs. d) In case of Co-operative Society Limited, Companies etc. this type of jobs must be included in the object of their By-laws or MoA as the case may be. 13. Submission of the Tender:- 14. Rates :- a) Bidder at their own cost shall have to submit Tender at the office of Principal Investigator, BRNS-DAE Project within the schedule date and time as mentioned in the Tender Notification No. BRNS/BP/T/01/ dated b) The said sealed documental bids will be opened by the Tender Purchase Committee in presence of the Bidders or representative of the Bidders who may be present in the opening date & time. a) Rates should be clearly quoted in both in figures and words in respect of each item. Rate should be quoted inclusive of all Taxes. VAT & Service tax. All corrections must be initialed.

11 In the event of the tender being submitted by a firm, it must be signed separately by each member thereof, or in the event of absence of any partners, it must be signed on his behalf by a person holding Power of Attorney authorizing him to do so. Such Power of Attorney is to be produced with the Tender and in the case of the firm, carried on by one member of Joint Family, it must be disclosed that the firm is duly registered under the Indian Partnership Act. 18. Necessary proof as to the financial status of the individual and firm tendering is to be attested and submitted. 19. Tender Form with all the relevant papers in details shall be essential part of the Tender. 20. Before submission of the Tender, Tenderer shall sign each page of his Tender and all of its relevant papers with date. The additional alternative and or subtractive clause (if any) shall also to be signed by the tenderer. 21. Warranty:- The Seller declares that the goods, stores articles sold/supplied to the Buyer under this Supply Order shall be the best quality and workmanship and new in all respects and shall be strictly in accordance with the specification and particulars contained/mentioned in Supply Order. The Seller guarantees that the said goods/stores/articles would continue to conform to the description and quality aforesaid for a period of 36 months from the date of installation of the said goods stores/articles to the Buyer. 24. Rate must be valid for entire tender period, which, if the Institute authority desires, may be extended for further period issuing proper notification. 25. Acceptance of lowest tender is not obligatory.

12 The PI, BRNS-DAE Project reserves all rights to accept or reject any Tender without showing any reason. 28. The Tender, submitted by the firm who have already been declared as Black Listed or whose contract was terminated for dissatisfactory supply or repairing works or who was unable to execute any repairing order in this University or in any other University run by the state or central government., will not be considered even his being the lowest rate. 29. Regarding Supply and Charges for repairing, Abnormal Low Rate or Abnormal High Rates (in comparison to the market Rate) will not be considered. PI, BRNS-DAE Project SIGNATURE OF THE BIDDER

13 13 ANNEXURE 1 TECHNICAL BID FORMAT: 1 Name of the firm/ Society/ Company/ Proprietary Concern 2 Address of registered office 3 Address of the office at Patna 4 Telephone Nos./Fax/ at Patna 5 Banker of Company/ Firm/agency with full address Telephone Number of Banker 6 PAN / GIR No. 7 VAT/SALE TAX Reg. No. (Attach attested copy) 8 Service Tax Registration No. (Attach attested copy) 9 Details of clients along with address, telephone and Fax numbers, Amount of contract, Date: Place: (Signatures of the authorized signatory with seal of tendering firm) Name:- Address:-

14 Mob. No. - 14

15 15 ANNEXURE 2 PRICE BID FORM To, Principal Investigator, BRNS-DAE Project Microbial & Molecular Genetics Lab, Department of Botany, Patna University Patna Dear Sir, 1. I/We... submitted the bid for Tender No. BRNS/BP/T/01/ Dated: I/We thoroughly examined and understood instructions to tenders, scope of work, terms & conditions of contract given in the tender document and those contained appendix of Terms & Conditions of contract and agree to abide by them. 3. I/We hereby offer to supply of HPLC at the following rates. I/We undertake that I/We are not entitled to claim any enhancement of rates on any account during the tenure of the contract. Rate Rate Quoted Quoted per per Unit Unit Sl. No. Items Qty. inclusive of all inclusive of taxes (In all taxes (In Words) Figures) 1 HPLC System 1 (Signature of Authorised Person) (Name) (Designation) Name of Firm/Company/Agency Contact Details

16 16 Pump should have following features: Technical Specification of HPLC system Hydraulic system Dual piston in series pump with servo-controlled variable stroke drive, floating pistons. Settable flow range Set points ml/min, in ml/min increments. Flow range ml/min Flow precision 0.07 % RSD or 0.02 min SD, whatever is greater; based on retention time at constant room temperature. Flow accuracy ± 1 % or 10 µl/min whatever is greater; pumping degassed H2O at 10 MPa (100 bar). Pressure operating range suitable for Quaternary pump: Operating range up to 40 MPa (400 bar, 5880 psi) up to 5 ml/min Operating range up to 20 MPa (200 bar, 2950 psi) up to 10 ml/min Pressure pulsation < 2 % amplitude (typically < 1.3 %) or < 0.3 MPa (3 bar), whatever is greater, at 1 ml/min isopropanol, at all pressures > 1 MPa (10 bar, 147 psi). Compressibility compensation User selectable, based on mobile phase compressibility. Recommended ph range , solvents with ph < 2.3 should not contain acids which attack stainless steel. Gradient formation Low pressure quaternary mixing/gradient capability using high-speed proportioning valve. Delay volume µl, dependent on back pressure; measured with water at 1 ml/min (water/caffeine tracer). Composition range 0-95 % or %, user selectable. Composition precision < 0.2 % RSD or < 0.04 min SD, whatever is greater, at 1 ml/min; based on retention time at constant room temperature. Integrated degassing unit Number of channels: 4 Internal volume per channel: 1.5 ml Materials in contact with solvent: TFE/PDD Copolymer, FEP, PEEK, PPS System should have manual injector with the system. Variable UV Detector should have following features: Detection type Double-beam photometer

17 17 Light source Deuterium lamp Number of signals 1 Maximum data rate:13hz Noise < ± 0.25 x 10-5 AU, at 230 nm Drift 1 x 10-4 AU/hr, at 230 nm Linearity >2.5 AU upper limit Wavelength range nm Wavelength accuracy ± 1 nm, self-calibration with deuterium lines, verification with holmium oxide filter Slit width 6.5 nm typical over whole wavelength range Time programmable Wavelength, polarity, peak width, lamp on/off Flow cells Standard: 14 µl volume, 10 mm cell path length and 40 bar (580 psi) pressure maximum Spectral tools Stop-flow wavelength scan RI Detector should have following features: Detection type Deflection method Short-term noise ±2.5 x 10-9 RIU Drift < 200 x 10-9 RIU/h Refractive index range , calibrated Flow cell 8 µl, 5 bar pressure maximum Temperature control Ambient +5 C to 55 C ph range Time programmable Polarity, peak width Zero adjustment Automatic zero Valves Automatic purge and automatic solvent recycle. Data rate Up to 37 Hz System should be equipped with software which is designed for the advanced needs of research and development scientist. Should have features like instrument control, data storage, methods and sequences, method download, upload & new method set up in lab, file naming conventions, data acquisition, data analysis, reporting, customization, automation, run queue and queue planner, with maintenance feedback,good laboratory practice & data structure etc.

18 18 Oven should have following features: Peltier cooling and heating for maximum temperature stability and application flexibility. Spacious column racks hold up to three full-length, 30 cm columns. Optional 2-position/6-port switching valve for 600 bar operation. Simultaneous column identification of two columns for faster operation and reduced laboratory costs. Independent heat exchangers with settable values facilitate two different temperature zones. Low internal volume contribution of just 9 µl for low dispersion Temperature range 10 degrees below ambient to 80 C Temperature stability ± 0.15 C Temperature accuracy ± 0.8 C with calibration ± 0.5 C Column capacity Three 30 cm columns Heat-up/cool-down time 5 min from ambient to 40 C 10 min from 40 C to 20 C Internal volume 3 µl left heat exchanger 6 µl right heat exchanger System should come along with C x 150 mm, 5 µm columns & Sugar Analysis column Hi-Plex H, 300 x 7.7 mm Computer and Printer: Quote the price of HPLC system with and without Computer and Printer. System should have safety & maintenance features like extensive self-diagnostics for leak detection, safe leak handling, error detection and display through software, and leak output signal for shutdown of the pumping system. Kept monitoring low voltage in major maintenance areas. System should have original licensed software with following facility like instrument control, data storage, methods and sequences, method download, upload & new method set up with manufacturing consultancy in lab, file

19 19 naming conventions, data acquisition, data analysis, reporting, customization, automation, run queue and queue planner, good laboratory practice & data structure etc. System should have standard GLP features for early maintenance feedback for continuous tracking of instrument usage in terms of seal wear and volume of pumped mobile phase with pre-defined and user settable limits and feedback messages. Electronic records of maintenance and errors. Quotation should be submitted along with original technical brochures supporting their specifications from manufacturer

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