SLIM -1.69% 2.05% 5.95% 4.14% SLIM (NAV) -3.15% 1.54% 5.19% 2.84% Solactive Obesity Index

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1 The Obesity ETF ETF.com segment: Equity: Global Health Care Competing ETFs: IXJ Related ETF Channels: Theme Investing, Sectors, Global, Healthcare, Equity, Vanilla, Broad-based Find more ETFs with our ETF Screener and Database *Unless otherwise stated, data provided by FactSet. FUND DESCRIPTION is a market cap selected and weighted fund that focuses on companies from all over the world positioned to serve the obese. FACTSET ANALYTICS INSIGHT Janus s is an ETF that builds its portfolio with stocks oriented towards different facets of obesity. The majority of s holdings reside in the healthcare, and the treatment of complications associated with obesity (diabetes, high blood pressure, cholesterol, heart disease, stroke, and sleep apnea), but also includes companies that focus on weight loss programs, as well as plus-sized clothing. The fund selects its constituents from both developed and emerging markets from all over the world. It is worth noting the fund has a significant portion of its holdings invested in just a couple stocks. MSCI ESG ANALYTICS INSIGHT The MSCI ESG Fund Quality Score measures the ability of ETF underlying holdings to manage key medium to long-term risks and opportunities arising from environmental, social, and governance factors, as determined by MSCI ESG Research LLC. As of April 14, 2019 the The Obesity ETF MSCI ESG Fund Quality Score is 6.10 out of 10. The fund s Peer Rank reflects the ranking of a fund s MSCI ESG Fund Quality Score against the scores of other funds within the same peer group, as defined by the Thomson Reuters Lipper Global Classification. ranks in the 93th percentile within its peer group and in the 70th percentile within the global universe of all funds in MSCI ESG Fund Metrics coverage. SUMMARY DATA Issuer Inception Date Legal Structure Expense Ratio Assets Under Management Average Daily $ Average Spread (%) PORTFOLIO DATA Weighted Average Price / Earnings Ratio Price / Book Ratio Distribution Yield Next Ex-Dividend Date Number of Holdings INDEX DATA Index Tracked Index Weighting Methodology Index Selection Methodology Janus Henderson 06/08/16 Open-Ended Fund 0.35% $13.54M $61.22K 1.48% $26.37B % Solactive Obesity Index Thomson Reuters Global Healthcare 1 Year PERFORMANCE [as of 04/12/19] 1 MONTH 3 MONTHS YTD 1 YEAR 3 YEARS 5 YEARS 10 YEARS -1.69% 2.05% 5.95% 4.14% (NAV) -3.15% 1.54% 5.19% 2.84% Solactive Obesity Index Thomson Reuters Global Healthcare All returns over 1 year are annualized. All returns are total returns unless otherwise stated. TOP 10 COUNTRIES TOP 10 SECTORS

2 TOP 10 HOLDINGS PORTFOLIO MANAGEMENT TAX EXPOSURES FUND STRUCTURE Expense Ratio Median Tracking Difference (12 Mo) Max. Upside Deviation (12 Mo) Max. Downside Deviation (12 Mo) 0.35% Max LT/ST Capital Gains Rate Capital Gains Distributions (3 Year) Tax on Distributions Distributes K % / 39.60% Qualified dividends No Legal Structure OTC Derivative Use Securities Lending Active Securities Lending Split (Fund/Issuer) ETN Counterparty Open-Ended Fund No Yes No Policy ETN Counterparty Risk Fund Closure Risk High Portfolio Disclosure Daily

3 Daily Spread Premium/Discount FACTSET ANALYTICS BLOCK LIQUIDITY As of 04/15/ This measurement shows how easy it is to trade a $1 million USD block of. is rated a 3 out of 5. TRADABILITY Avg. Daily Share Average Daily $ Median Daily Share Median Daily ($) Average Spread (%) Average Spread ($) Median Premium / Discount (12 Mo) Max. Premium / Discount (12 Mo) Impediment to Creations Market Hours Overlap Creation Unit Size (Shares) Creation Unit/Day (45 Day Average) Creation Unit Cost (%) Underlying / Unit Open Interest on ETF Options Net Asset Value (Yesterday) ETF.com Implied Liquidity 1,727 $61.22K 1,173 $.79K 1.48% $ % 2.48% / -2.80% None 59.00% 100, % 0.83% $ SECTOR/INDUSTRY BREAKDOWN TOP 10 HOLDINGS PERFORMANCE STATISTICS Healthcare Equipment & Supplies 42.27% 22.58% Pharmaceuticals 20.74% 50.84% Healthcare Providers & Services 12.59% 10.72% Novo Nordisk A/S Class B Fresenius Medical Care AG & Co. KGaA Resmed Inc CHESS Depositary Interests on a ratio of 10 CDIs per ord.sh ABIOMED, Inc. Insulet Corporation 22.25% 9.44% 7.57% 6.08% 5.85% Goodness of Fit (R2) Beta Up Beta Down Beta Downside Standard Deviation % Thomson Reuters Global Healthcare DexCom, Inc. 5.42% MSCI ESG RATINGS

4 Personal & Household Products & Services 8.65% 0.08% Fisher & Paykel Healthcare Corporation Limited DaVita Inc. 5.00% 4.42% MSCI ESG Quality Score Peer Group Percentile Rank 6.10 / Biotechnology & Medical Research Food & Tobacco Other Specialty Retailers 7.33% 11.24% 1.82% 0.13% 0.85% Tandem Diabetes Care, Inc. Herbalife Nutrition Ltd. Total Top 10 Weighting 4.30% 4.21% 74.54% Global Percentile Rank SRI Screening Criteria Exposure Exposure to Sustainable Impact Solutions Weighted Average Carbon Intensity (t CO2e/$M Sales) % COUNTRIES United States 61.68% 65.70% Denmark 20.41% 1.59% Germany 8.27% 2.55% New Zealand 4.65% 0.19% Japan 2.26% 6.43% Hong Kong 1.60% 0.94% United Kingdom 0.47% 3.90% BENCHMARK COMPARISON HOLDINGS Number of Holdings Constituents Shared Holdings Shared Holdings Weight BENCHMARK COMPARISON SUMMARY % Taiwan, Province of China 0.42% 0.04% France 0.16% 2.84% Number of Holdings 883 Israel 0.07% 0.23% REGIONS Weighted Average Market Cap $26.37B $110.32B North America 61.68% 66.15% Europe 29.32% 21.32% Price / Earnings Ratio Price / Book Ratio Asia-Pacific 8.93% 12.00% Middle East & Africa 0.07% 0.44% Latin America 0.09% Dividend Yield 1.00% 1.76% Concentration High Low ECONOMIC DEVELOPMENT Developed Countries % 98.30% Emerging Countries 1.70%

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