Research Infrastructures for Biomedical sciences

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Research Infrastructures for Biomedical sciences 16, Brussels DG RTD Structuring ERA

Objectives What Research Infrastructures are needed for Biomedical Sciences? What appropriate size and nature of Research Infrastructures for responding to these needs? What funding mechanisms under FP7?

Introduction (H. Pero) Bio-repositories (M. Hrabé de Angelis, S. May) Protein structure determination (M. Weiss, L. Banci) Genomics and Proteomics (S. Fey, U. Landegren, P. Boisseau) Survey on Research Infrastructures (H. Karow, H. Wang, J-E Faure, F. Marcus) Round table Agenda (a.m.)

ESFRI work (T. Hall, E. Curtius, J. Duszynski) Bio-informatics (J. Thornton, V. Paces) Imaging facilities (R. Frackowiak, A. Engel, W. Hax) X-Ray radiation therapy (D. Schulz-Ertner) Clinical research (O. Blin) Round table Agenda (p.m.)

History of European Research ECSC Research JRC Creation Treaties fusion First Specific Programmes Amsterdam Treaty Maastricht Treaty Euro 1951 55 57 67 84 87 90 91 93 94 97 98 2002 2006 84 87 9091 9394 97 9899 ECSC Treaty EEC/ EURATOM Treaties FP- 1 FP- 2 FP- 3 FP- 4 Single Act FP- 5 FP- 6 The European Union s research is implemented through framework programmes

An integrated and Responsible Approach Research activities at EU level require action on several fronts Societal Issues Infrastructure International Cooperation Industrial Innovation Research and Development Human Resources Health, safety, environmental and consumer protection

Community RTD: the changing priorities 100 90 Dissemination & exploitation 80 International cooperation % 70 60 50 Human Resources + Infrastr Socio-economic Food quality Life sciences 40 IT and Communications 30 20 10 SMEs Industrial & materials technology Aeronautics & space Transport 0 Environment 1982 FP1 FP2 FP3 FP4 FP5 FP6 Energy

FP7 (2007-2013) will continue to strengthen European research Stimulation of collaboration Joint research initiatives Human potential + Scientific infrastructures Competition for excellence ERC Long Term Persistency Coordination between MS

A first reminder Research Infrastructures are defined under the Framework Programme as follows: Facilities, the capacity and performance of which offer to the scientific community the tools and/or services needed for the development of leading-edge research, of fundamental or applied character; Such facilities can be "single-sited, distributed or virtual.

Research Infrastructures are at the core of the knowledge Triangle Research Research infrastructures Education innovation

The EC objectives are supported by the statements of the Council (1-3 July 2004): F Reinforcement of research capacities F Prevention of fragmentation F Increased co-operation F Need to develop a European roadmap F Increased role of ESFRI

The EC objectives further supported by the statements of the Council (25 November 2004): F Reinforcement of existing actions F Strengthened and coherent EU policy F Welcomed ESFRI roadmap F Need to identify vital new RIs F Need for appropriate support mechanisms

Survey of European Research Infrastructures RI reported to be of top-level relevance & having a clear European dimension and Total investment for construction of RI > 20 Mio

Research Infrastructures in FP7 : Two proposed main lines of action Continuation and improvement of the current (mainly bottom-up ) approach for optimizing the access to and the utilisation and performance of existing infrastructures Implementation of a «strategic» approach for developing future infrastructures of pan- European interest (incl. major upgrades)

In brief Research Infrastructures Existing Future Strategic Bottom-up Support of excellence Optimisation of Resources Support of ideas (pre-studies) Reinforcement of Capacities (engineering support of pan-european RIs) ESFRI Roadmap

There is also a need for an increased role of EU at international level based on development of concrete actions and on a better cooperation at this level (e.g. within the Global Science Forum) Photo NASA/ESA/ASI Cassini-Huygens spacecraft for further information see http://www.cordis.lu/infrastructures/

a) Continuation, improvement and reinforcement of the existing schemes F to optimise the use of infrastructures and to improve their performance Access to research infrastructures Integrating activities (networking, coordinated access, research activities) Communication Network Development Design Studies (for new infrastructures) F Call for proposals (incl. co-management with thematic priorities); selection through a peer review system.

Supporting access to individual infrastructures Other example: the Brain Research Unit Helsinki, Finland To study functions of the human cerebral cortex by measuring magnetic fields Neuro-BIRCH III (FP5, TA, 0.54 million euro) State-of-the-art biomagnetic recording instruments

Integrating infrastructures Synchrotrons in Europe Biomedical applications such as:? Coronary angiography? Tomography studies? Mammography using diffraction-enhanced imaging? Microbeam radiotherapy for cerebral tumors? Photon activation therapy

b) An increased strategic approach of FP7 F Support for the development of new research infrastructures of EU interest based on : 1. a strategic long term vision for research infrastructures (roadmap) 2. Targeted support for specific research infrastructure projects 3. Increased use of financial engineering mechanisms to support them

A clear vision of the needs for research infrastructures in the medium long term should be defined as well as a corresponding roadmap. The European Strategy Forum on Research Infrastructures (ESFRI) will play a major role in this context. http://www.cordis.lu/era/esfri_home.htm

European roadmap for RI A transparent methodology, recognized by all stakeholders Agreed criteria : - Science case, - EU dimension, - Impacts, - Maturity (e.g. timetable, budget, possible partnership, ) Under a continuous process, with annual updates

An important role for ESFRI but also of other stakeholders To promote common approaches to EU Research Infrastructures To support the timely development of a coherent strategy for EU RIs To facilitate multilateral initiatives involving all relevant stakeholders Inputs are expected from e.g. EIROs, ESF, industrial bodies,, ETPs,

List of priority projects To be established by the Commission on the basis of the roadmap - «balanced», periodically updated - with justifications for each project Using clear criteria: potential impact (Lisbon, reduced fragmentation of efforts), timeliness, readiness, budgetary planning, quality of management,

Efficient long term management and financial engineering are needed due to the very long life time of such infrastructures FEDER BEI M Construction National support Users EU-FP support Time Upgrades and interconnections Pre-studies Engineering Running costs 20 to 50 years

Increased use of financial engineering to support new research infrastructures Member states European Commission Stakeholders incl. EIROs Inclusion in national Programmes Inclusion in Specific RTD Programme(s) Inclusion in FEDER RELEX strategic plans Projects EIB

A two-stage process : The operational mechanism within FP7 Preparatory phase - through restricted calls targeted to the list of priority projects - for construction plans, legal organisation, management structure, Implementation phase - following successful first phase - for concrete construction and operation - engineering various financial instruments

In conclusion, FP7 will Continue and improve the current Community actions for optimizing the access to and the utilisation and performance of existing infrastructures Help to develop a forward-looking «strategic» approach for the creation of key infrastructures (singlesited, distributed or virtual) of pan-european interest, in the medium-long term

An active Commission s role Acting as a facilitator for the overall projects - leveraging and catalysing action, - financial engineering, - legal framework, Coordinating the Community instruments (Framework Programme, Structural Funds, EIB) and assessing consistency of actions Ensuring monitoring of the projects

Calendar to consolidate an EU policy on RIs 1. Agreement on the approach 2. Consolidation of work 3. Analysis of current activities ; Survey; Vision for the future 4. Analysis of ESFRI roadmap for future RIs and of operational mechanisms 5. Presentation of specific programmes October 2004 December 2004 Spring 05 Summer 05 Autumn 2005 FP7 proposal would be presented by the Commission on April 2005