Merck FY/Q Financial Summary for Investors and Analysts

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Merck FY/Q4 2014 Financial Summary for Investors and Analysts Strategic progress and delivery of results in 2014: Closing and successful integration of AZ Electronic Materials Announcement of Sigma-Aldrich acquisition Signing of alliance with Pfizer to leverage ionc pipeline Delivery on targets: Sales 11.3 bn, EBITDA pre 3.388 bn, EPS pre 4.60 Organic growth across all divisions Rapid deleveraging following AZ acquisition FY 2015 guidance: EBITDA pre slightly higher - at least stable; slight organic sales growth Overview Financials Q4 2014 Overview Organic growth, portfolio effects as well as currency tailwinds drive sales EBITDA pre and EPS pre improve on solid organic performance and AZ despite loss of royalty income Operating cash flow includes Pfizer upfront payment Only slight increase in financial debt, AZ acquisition digested within a year Higher headcount includes employees from AZ YE 2014 Balance Sheet Balance sheet reflects AZ acquisition and Pfizer collaboration Issuance of hybrid bond impacts cash and debt Provisions for pensions up due to lower interest rates FX development accounts for ~ 1 bn total balance sheet increase FY 2014 Cash flow Statement Decrease in D&A YoY due to 2013 impairments Changes in provisions reflect release from litigation settlement Changes in other assets/liabilities increase from Pfizer upfront payment Investing cash flow reflects payment for AZ and cash investments in short term assets Capex increases mainly due to investment in new plant in China Financing cash flow positive mainly driven by cash in from hybrid bond; last year reflects bond repayment 1

Q4 2014 Business Overview Merck Serono Emerging Markets drive organic growth Sales deviation YoY: organic +2.8%, FX +2.7%, portfolio 0% Rebif organically lower as European and U.S. volume losses to competition from oral therapies outweigh U.S. pricing initiatives Erbitux with good organic performance driven by commercial initiatives in Emerging Markets Strong demand for entire Fertility portfolio in all regions Continued pipeline prioritization (pimasertib, Sym004) increase R&D expenses EBITDA pre increases due to organic growth; litigation settlement balances one-time R&D expenses and higher LTIP * provisions Consumer Health Strong volumes amid investments in marketing and selling Sales deviation YoY: organic +6.5%, FX +2.7%, portfolio 0% Sound organic sales growth supported by currency tailwinds Investments in global marketing initiatives drive growth in Emerging Markets, especially Neurobion and Floratil in Brazil Good performance of cough and cold products in Europe Femibion reaches record market share in Germany EBITDA pre almost stable as organic growth is offset by higher marketing and selling costs Performance Materials A strong quarter Sales deviation YoY: organic +6.9%, FX +5.8%, portfolio +37.5% Sales jump on portfolio effect, strong organic growth & FX tailwinds Volume growth in Liquid Crystals remains largest contributor to organic performance Strong demand for ultra-high-definition TV s (PS-VA) and mobile devices (IPS & UB-FFS) key success factor Significant EBITDA pre increase driven by AZ and strong organic growth EBITDA pre margin reflects mix effect from AZ * Long Term Incentive Plan 2

Merck Millipore Process Solutions drives growth Sales deviation YoY: organic +5.9%, FX +3.4%, portfolio -1.2% Good organic growth and FX, slightly offset by portfolio changes Strong demand from biopharma industry for single-use equipment and purification consumables drives growth at Process Solutions Lab Solutions with good performance from price and volume uptakes especially in lab water consumables Bioscience almost flat as good development of separation and preparation products is offset by low demand for antibodies EBITDA pre affected by investments in marketing and selling, higher LTIP provisions and unfavorable product mix 2015 guidance (on existing platform): Merck Group: EBITDA pre: slightly higher at least stable Sales: slight organic sales growth Outlook by business sector: Healthcare Organically stable top line Rebif decline Growth in other franchises EBITDA pre slightly lower Life Science Moderate organic sales growth Process solutions key growth contributor Moderate EBITDA pre increase Performance Materials Slight organic growth Strong AZ portfolio effect leads to low double-digit EBITDA pre increase Additional financial guidance Merck Group royalty, license and commission income in 2015 ~ 300 m Corporate EBITDA pre: at least - 220 m Underlying tax rate: ~ 23% to 25% Capex on PPE and software: ~ 600 m 3

Merck Group Q4 Group Merck Serono Consumer Health Performance Materials Merck Millipore Corporate/Others m Q4 2013 Q4 2014 % YoY Q4 2013 Q4 2014 % YoY Q4 2013 Q4 2014 % YoY Q4 2013 Q4 2014 % YoY Q4 2013 Q4 2014 % YoY Q4 2013 Q4 2014 % YoY Sales 2,636 2,976 13% 1,419 1,497 6% 180 197 9% 383 576 50% 654 706 8% % organic 4% 3% 6% 7% 6% % FX 3% 3% 3% 6% 3% % portfolio 5% 0% 0% 38% -1% EBIT 264 424 60% 116 244 >100% 36 34-5% 134 170 27% 51 55 9% -72-80 11% Depreciation and amortization 462 380-18% 339 233-31% 2 3 63% 21 59 >100% 95 80-16% 5 5-2% EBITDA 726 804 11% 455 478 5% 38 37-2% 155 229 48% 145 135-7% -67-75 12% One-time items on EBITDA 69 74 7% 20 15-29% 1 1-43% 11 10-13% 22 28 23% 14 21 55% EBITDA (pre-one time items) 795 878 10% 475 492 4% 39 38-3% 167 239 44% 168 163-3% -54-54 0% Merck Group FY Group Merck Serono Consumer Health Performance Materials Merck Millipore Corporate/Others m FY 2013 FY 2014 % YoY FY 2013 FY 2014 % YoY FY 2013 FY 2014 % YoY FY 2013 FY 2014 % YoY FY 2013 FY 2014 % YoY FY 2013 FY 2014 % YoY Sales 10,700 11,291 6% 5,688 5,783 2% 742 766 3% 1,642 2,060 25% 2,628 2,682 2% % organic 4% 4% 5% 4% 5% % FX -2% -2% -2% -1% -2% % portfolio 3% 0% 0% 23% -1% EBIT 1,611 1,762 9% 793 957 21% 162 150-8% 653 611-6% 262 289 10% -260-245 -6% Depreciation and amortization 1,458 1,361-7% 993 830-17% 9 10 18% 112 192 71% 328 310-6% 16 19 22% EBITDA 3,069 3,123 2% 1,787 1,786 0% 171 160-6% 766 804 5% 590 599 2% -244-226 -7% One-time items on EBITDA 184 265 44% 69 45-35% 1 9 >100% 14 91 >100% 53 60 13% 47 60 27% EBITDA (pre-one time items) 3,253 3,388 4% 1,855 1,831-1% 172 169-2% 780 895 15% 643 659 2% -197-166 -16% Net financial debt* 307 559 82% * as per 31 December 4

Merck Group P&L Group Q4 2013 Q4 2014 % YoY Sales 2,636 2,976 13% Royalty, license and commission income 105 60-43% Total revenues 2,742 3,036 11% Cost of sales -790-988 25% thereof: intangibles amortization -12-39 >100% Gross profit 1,952 2,048 5% Marketing and selling expenses -766-827 8% thereof: intangibles amortization -184-177 -4% Royalty and commission expenses -130-128 -2% Administration -155-169 9% Other operating income/expenses -291-76 -74% Research and development -346-424 23% EBIT 264 424 60% Depreciation and amortization 462 380-18% EBITDA 726 804 11% One-time items on EBITDA 69 74 7% EBITDA (pre-one time items) 795 878 10% Financial result -63-63 0% Profit before tax 201 361 79% Income tax 80-79 n.m. Income tax rate -40% 22% Profit after tax 281 282 0% Non-controlling interest -1-2 >100% Net income 281 280 0% Number of theoretical shares in million 434.8 434.8 EPS in 0.65 0.64-2% EPS (pre one-time items) in 1.06 1.14 8% 5

Merck Serono P&L MS Q4 2013 Q4 2014 % YoY Sales 1,419 1,497 6% Royalty, license and commission income 101 55-45% Total revenues 1,520 1,552 2% Cost of sales -286-325 14% thereof: intangibles amortization 0 0 n.m. Gross profit 1,234 1,227-1% Marketing and selling expenses -449-459 2% thereof: intangibles amortization -143-134 -6% Royalty and commission expenses -125-124 0% Administration -53-56 5% Other operating income/expenses -226-20 -91% Research and development -265-323 22% EBIT 116 244 >100% Depreciation and amortization 339 233-31% EBITDA 455 478 5% One-time items on EBITDA 20 15-29% EBITDA (pre-one time items) 475 492 4% Consumer Health P&L CH Q4 2013 Q4 2014 % YoY Sales 180 197 9% Royalty, license and commission income 1 1 18% Total revenues 181 198 9% Cost of sales -63-68 8% thereof: intangibles amortization 0 0 n.m. Gross profit 118 130 10% Marketing and selling expenses -72-86 19% thereof: intangibles amortization -1-1 11% Royalty and commission expenses -1 0-93% Administration -9-7 -18% Other operating income/expenses 4 5 24% Research and development -5-7 64% EBIT 36 34-5% Depreciation and amortization 2 3 63% EBITDA 38 37-2% One-time items on EBITDA 1 1-43% EBITDA (pre-one time items) 39 38-3% 6

Performance Materials P&L PM Q4 2013 Q4 2014 % YoY Sales 383 576 50% Royalty, license and commission income 1 0-88% Total revenues 384 576 50% Cost of sales -151-279 84% thereof: intangibles amortization -1-27 >100% Gross profit 232 296 28% Marketing and selling expenses -36-50 40% thereof: intangibles amortization -3-4 28% Royalty and commission expenses 0 1 n.m. Administration -6-15 >100% Other operating income/expenses -19-13 -30% Research and development -37-48 31% EBIT 134 170 27% Depreciation and amortization 21 59 >100% EBITDA 155 229 48% One-time items on EBITDA 11 10-13% EBITDA (pre-one time items) 167 239 44% Merck Millipore P&L MM Q4 2013 Q4 2014 % YoY Sales 654 706 8% Royalty, license and commission income 3 4 20% Total revenues 657 710 8% Cost of sales -288-314 9% thereof: intangibles amortization -12-12 2% Gross profit 369 396 7% Marketing and selling expenses -206-231 12% thereof: intangibles amortization -37-39 4% Royalty and commission expenses -4-4 6% Administration -25-30 21% Other operating income/expenses -45-33 -27% Research and development -38-43 12% EBIT 51 55 9% Depreciation and amortization 95 80-16% EBITDA 145 135-7% One-time items on EBITDA 22 28 23% EBITDA (pre-one time items) 168 163-3% 7