Notice of Initial subaar*lai

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1 / Fo,m 603 Ovito,/0,1/gtlll 0.2*11871i Notice of Initial subaar*lai holder nlarl -811*nae:h,i» "04/Ii:- JB MI-Fl UMITED il/'de//wh//#) *M Pa*RSNM*4 YARKA FUNDS MANAGEMENT UNITED KN (WM]; YARRA CAPrTAL MANAGEMENT HOLDINGS PTY LTD ACN ( 001); YARRA MANAGEMENT NOMINESS PTY LTD ACN (YMN); UAUmALIA FINCO PTY LTD A (ANCO}; TA SP AUSTRALIA TOPCO m LTD ACN (TOKO); TA UNIVERSAL INVES ENT HOLDINGS LT[) (UI#VmAL) See abor e 1.ME<-a...kon 31/ libd Wligpl... h -rullb,or,- *mot»did/. W.Un- &10» 601.vor,*Ig Im,Imbm.4.INEI.*09 *h-=m.04*94 Ma/,0... h m...=-a".0. 1-,=. M-..4.laill.0 In*0/9/Al// P=*WI.f % 1 00*il.1.4,0.'..Ii. 11. lk.dil.*u.m...id.#,h..# W#/=..."1.B....hok.=r. m.trt.. YCMH Illkiliwililli,filillit02 Relevant Interest pursuant to 8608(3)(b) of the Corporations A t (CA), belr a relevant irrterest held through, body corporate (YEM) that YCMH controls...w Mt,rof,IotrR. / YFM YMN FINCO TOPCO UNIVERSAL Relevant Interest pursuant to $608(1) of th, CA, boing thi power to exercbse or control the exercise of a rtht to vote attidid to th, securities,nd/or the pver to dbpose of securities m Investment manager of trustee, Relevant Intern$t pursuant to $608(3)(a) of the CA, being a r*i,vent Interest held through g body corpor,te (YCMH) In which N's voting power is more than 20% flelivint Inter,!st pursuant to $608(3)(,) of the CA, beins I relevant Imerest held through a body corporate (YCMH) In which FINCO'$ voting power Is more than 20% Relevant Interest pursuant to,600(3)(b) of the CA, bel: a releint imerest held through a body corporate (FINCO) that TOPCO contro s Relevant Interest pursuant to $608(3Xb) of thi CA, being. relevam Interest held through c body corporate (TOPCO) that UNIVERSAL controls / Ordinary Fully Paid Sh;res / Ordinary Fully Paid Sharn / / Ordinary Fully Paid Shirls /

2 803 FO,23 luily 01 * Ild**Wub 11» plione KIM I Wd»oll» sic, lii Ili,/lohps, h3*himinaa " Rm./.1/"al' M. Al substamial HSBC Custody Nomlneet (Australia) Limited; USS FM asthe Ordinary Fully holders named In Nominees Pty Lid responsible entity for Paid Shares / 1 above a mnged managld Investment schemes Allsubstantial National Australls Bank Asilt Servicing: BNP Parlbas Various alents of holders named in Securities Services; HSBC Bank Australia Limited; YFM l above JPMorumn Chase knk NA; St*te Street Australia Umlted; Clt*roup Pty Umlted; Invt@ Custodian Pty Limited; North,m Trust Compeny; National Nominees Umlted Ordinary Fully Paid Shares/ 4,949,791 a CH...Rn 11 =lame,1 I l,let litliii/-=ibl:..,ple,balitj =z, tlhliabrrr *l pluidu»* MI» IMImhcIi h-ad..11,...w 4.4 =1.* C» 0=011 8'j'llon C * Sld r,02* ci YCMH YFM YMN FINCO TOPCO UNIVERSAL Refer to Attlchment A Rlfer to Attachment A» I,lall Fair,Mhpilgipl!3ah,=I,Ii,/Ili, d Ihi IWI<Incld/milkta IVA.r NNU.of.led'din 7. AOI'"I- TI./.morp--Mmu ll.om...4z Iddi- YCMH EVEL 19,101 COLLINS STREET, MELBOURNE VICTORIA 3000 YPM LEVEL 19, 101 COLLINS STREET, MELBOURNE VICTORIA 3000 YMN LEVEL 19, 101 COLLINS STREET, MELBOURNE VICTORIA 3000 RNCO 58 GIPPS STREET, COLLINGWOOD VICTORIA 3066 TOPCO 58 GIPPS STREET, COLUNGWOOD VICTORIA 3066 UNIVERSAL 3RD FLOOR, DEVONSHIRE HOUSE 1 MAYFAIR PLACE, LONDON WlJ BAJ, UNITED KINGDOM *trim GARVIN LOUIS Mpe# COIJPAN 2 OP YFM signhe. di» 04 /09/ 17

3 003 p/0/23 16.Al,m ATTACHMENTA Form Notice of Inlt al Substantial Holder COI,/di,liOn 1:m Gorldi,li) plal#ii,milm/inimtim/lohpa glplutaq= 1=,Idht,Ihrrr=IM pl rlohedq litlii Indillhokitb on Dgte of Acqu ItIon 3-May May May May May May May May *lay *lay Mly *lay May May May *17, *m May Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Jul Jut JUI Jul Ju Jul-2017 Trins,don Type Purchase on m,rkst Purchme on mirket purchass on market Purch=e on m.*et Purchase onmarket Purchm on market -. purchal on market Pudise on markit Sold orl market Sold or) market Purchase on midux purchase onmarket Conaderation Cash $ $ $ $ $ $ $ $ $ $ $ $ ,6986 $ $ $ $ $ $ $ $ $ $ $ $ $ $ 22,8712 $ $ 23,6662 $ $ $ $ $ $ Non-cash rdll #11 Class and number of Securities Class Ordlniry Fully Paid Shares Ordinary Fully Pall Shares Ordinary Fully Pakd Shares Ordinary Fully paid Shares Ordinary Ful Paid Sharm Ordhilry Fully Paid Shares Ordinary Fulfr Pdd Shares Ordinary Fuily Paid Shares Ordmary Fully Paid Shares Ordinary Fully P,Id Shores Ordinary Fully Paid Sh,re Ordinary Fully Pald Shirss (*dinary Fully Paid Shares Ordltary Fully Paid ShareG Ordinary Fully Pald Share Ordinary Fully Paid Sluras Ordinary Fuly Paid Sh,rm Ordinary Fully Paid Share; Ordinary Fully Paid Sh,res Ordinary Fully pild Shares Ordinary Fully Pild Shirs 0rdlnary Fully Paid Shares Orrijwry Fully Paid Shares Ordinary Funy Paid Sharm Ordinary Fully Paid Sheri Number l

4 803 F 4/3 18* 01 6-Juk Jul Jul lul Jul Jul" Ju Jul Ju lul Jul Jul *Jul lul Jul Jul Jul Jul Jul * Juk Jwk Ju ul Jul Jul Jul Jul Jul Jul JuK Juk Jul ** Aug At* Aug Aug Aug Aug Aug * * Aug Aug Aus Aug Aug ** Aug.2017 Purchaid on market Purchase on markat Sold onmarket Purchase crl market Purchale on market Purchase on m,rket Purcha*e on market Sold on mark,t Purchase on m,rk*t Sold on mark t Sold ort mark*t Purchase on markst Transfer out purchas' 04 market Purchus. on market Sold ort market Purch.Ie on market Transfer out Purchase on mirket Purchase on m,net purchase on mirket Purd, se on mirket Purchase on marka $ 24,6200 $ $ $ $ 24$MOO $ $ $ $ $ $ $ $ $ $ 25,4976 $ $ 25.ONO $ $ 25,3200 $ $ $ $ $ $ $ 25,4900 $ $ $ 25.BOO $ $ $ $ $ $ $ $ $ $ $ $ $ $ $ $ 25-SON 25,4700 Nl NU N 11 N 11 Ntt N 11 Nn '411 N1 NU Ordnary Fully Pald Shares Ordinary Fully Pild Shares Ordlnar, Fully Paid Shares Ordinary Fully Paid Shara Ordinary Fully Pald Shares Ordin.ry Fulw Paid Sh,r,$ Ordinary Fully Pud Shares Ordinary Fully Paid Sharel Ordln,ry Fully paid Sh,m Ordinary fully Paid Shares Ord Iniry Fully Paid Sharm Ordlnar, Fully Paid Shares Ordinary Fully P*ld Shares Ckdlnary Fully Paid Sharis Ordinary Fully Paid Shires 0111mry Fully P,Id Sharie 0,111,ary Fully Paid Shares Ordinary Fully Pold Shares Ordinary Fully Pakl Shares Ordlnary Fully Pild Slures Ordinary Fully Paid Shars Ordin,ry Fully Pild Sh.res Ordinary Fully Paid Shirm 001nsfy Fully Pild Sh,res Ordlnery Fully P.Id 511.res Ordinary Fully pild Sh.res O,dinary Fully Paid Shares Ordrnary Fully Paid Shares Z

14-Aus-2017 15-Aug-2017 15*18-2017 15 Aug-2017 15-Aug-2017 16-Aug-2017 16-Aug.2017 16-Aug-2017 17 Aug.

5 14-Aus Aug * Aug Aug Aug Aug Aug Aug Aus Aug Aug Aug Aug Aug Aug Aug Aug AUS Aug * Aug Aug AUS Aug ** ** Aug Aus # * »Aug Aug Aug Aug Aug Aus Aug ** At*2017 purch*$0 on market PurGh,se on mirket Purchase on rn,rket Pwrch,se on market Purchase on mir%,t Purchase oil market Purdiase on market Sold on madcet Purchale on mariwl Purchete on rn.rket Purchale on markat Purchage on market Purchase on mark,t $ $ $ $ $ $ $ $ $ $ $ $ $ $ $ 25 A $ 25.MOO $ $ $ $ $ $ $ $ 25, $ $ $ $ $ 25.MOO $ $ $ $ $ $ 24,6334 $ $ 24,7498 $ $ $ $ $ $ NU N li Nit 803 Ordinafy Fully Paid Shares Ordlnuy FUlly 000 shares Ordinary Fully Pall Shares Ordinary Fully Paid Shires Ordinary Fully Paid Sh,rm Ordkimly Fully Paid Shares Ordlne Fully Pild Shares Ordinary Fully Paid Sheres Ordinary Fully Paid Shars 0,111ninv Fully Pild Sh,res Ordinlry Fully Pild Shars Ordinary Fully Pild Sh,rn Ordlnary Pully Paid Shares Ordtrafy Fully Paid Shares Ordlnery Fully Paid Shares Ordiniry Fully Pald Shirs Ordinary Fully P,Id Shares FOI &0 16.ki,zm

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For personal use only 805 +901* 15.1*2001 Form 605 C»,60,4 M Sm ke,im m. Notice of ceasing to be a substantial holder 22 Cl,WIV N.I.Agd,In,I SIRTEX MEDIML LTD 'il'uen'vi 078 188 122 1. Il 01 /&*SIII:///,0,// 11) YARRA FTIWDS