Please see accompanying Prescribing Information, including Patient Information, for Radicava, also available at radicava.com.

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1 We re here for you available at.

2 Helping You Navigate Access to Treatment Searchlight Support provides education and assistance for people who receive RADICAVA (edaravone) IV infusion and those who care for them. OUT-OF-POCKET COST SUPPORT OPTIONS INFUSION CENTER DIRECTORY CLINICAL EDUCATORS We can help you obtain co-pay assistance, if eligible, and find an infusion site of care that works for you. Enrolling in Searchlight Support is easy When your doctor submits your Benefit Investigation and Enrollment Form for RADICAVA, you can also be enrolled in Searchlight Support. One of our Care Coordinators will be assigned to you, and will offer care coordination and out-of-pocket cost support options that may be available to you. How we can help Enroll you in Searchlight Support Out-of-Pocket Assistance Program, if eligible * Help you navigate your insurance benefit options Help you find a site of care for your infusions Answer product-related questions about RADICAVA * For eligible patients with commercial insurance. Restrictions apply. A Care Coordinator will call you: Please answer when your caller ID reads: Your Dedicated Care Team Care Coordinators Ready to reach out to you Have questions about Searchlight Support? Clinical Educators Ready to answer your questions about RADICAVA available at.

3 Helping to Provide Affordable Access to RADICAVA (edaravone) IV infusion OUT-OF-POCKET COST SUPPORT OPTIONS Searchlight Support can answer questions about insurance coverage for RADICAVA. If you have commercial insurance coverage * Searchlight Support Out-of-Pocket Assistance Program $ 0 PAY AS LITTLE AS PER INFUSION If you re eligible, your Care Coordinator can enroll you in our Searchlight Support Out-of-Pocket Assistance Program to help you save on your deductible, co-pay and co-insurance costs for RADICAVA and for your infusion. * For eligible patients with commercial insurance. Restrictions apply. Searchlight Support Out-of-Pocket Assistance Program is for eligible patients who have private, commercial health insurance with prescription coverage for RADICAVA medication. Not valid for patients covered, in whole or in part, by government health insurance (ie, Medicare, Medicaid, VA, DoD, or other federal or state assistance programs). Other restrictions apply. $20,000 maximum program benefit for 12 months from the first eligible date of program participation. For full eligibility requirements and terms and conditions, ask your healthcare provider for a Searchlight Support Out-of-Pocket Assistance Program brochure or visit. Support for patients who are eligible for government-funded insurance We can provide information about government health plan coverage for RADICAVA, including: Medicare: medicare.gov/pubs/pdf/10050-medicare-and-you.pdf Social Security Disability Insurance: ssa.gov/disability Medicaid: medicaid.gov TRICARE/DoD/Veterans Administration: va.gov/vadodhealth/tricare.asp We can also refer you to independent foundations that may be able to assist you with out-of-pocket costs. Resources for patients who are uninsured We can provide information about the Searchlight Support Patient Assistance Program (PAP): The PAP is committed to helping patients in financial need who are uninsured Patients who meet program requirements may be able to receive medication at no charge for up to two years. Restrictions apply. See full terms and conditions at Call us to learn more or visit us online at available at.

4 Helping Provide Access to Your Treatment INFUSION CENTER DIRECTORY Once your doctor submits the Benefit Investigation and Enrollment Form for RADICAVA for you, a dedicated Care Coordinator is ready to help you find an infusion site of care. CLINICAL EDUCATORS Our friendly and knowledgeable Clinical Educators can: Answer product-related questions about RADICAVA Provide educational resources on ALS and RADICAVA Connect you to other Searchlight Support services, if needed Remember that your doctor is the best person to talk to if you have questions about your treatment or your medical condition. DOCTOR S OFFICE If you receive RADICAVA outside your home, Searchlight Support can help you find an infusion site of care that is based on: Where you live Your insurance INFUSION CENTER Hours of operation HOSPITAL HOME Call us to learn more or visit us online at Contact Searchlight Support to learn more. available at.

5 We re here for you OUT-OF-POCKET COST SUPPORT OPTIONS We can help you obtain co-pay assistance, if eligible INFUSION CENTER DIRECTORY We can help you find an infusion site of care CLINICAL EDUCATORS We are available to answer questions about RADICAVA Radicava and the Radicava logo are registered trademarks of Mitsubishi Tanabe Pharma Corporation. Searchlight Support is a registered trademark of Mitsubishi Tanabe Pharma America, Inc. For US audiences only Mitsubishi Tanabe Pharma America, Inc. All rights reserved. CP-RC-US /18

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