U.S. Employee Benefits Overview

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U.S. Employee Benefits 2018 Overview

Welcome: Alnylam Benefits Offering a robust Benefits Program is an integral part to Alnylam s culture of investing in its employees health and well-being. We continually review our benefit offerings to ensure we keep pace with the market and meet the needs of our growing and diverse employee population. We are a company positioned for tremendous growth and investing in our employees is crucial to our success and ultimately to helping our patients lead better lives. Our benefit plans are just one of the many ways Alnylam helps employees take care of themselves and their family. We invite you to review this brochure which provides an overview of the benefits available to regular employees.

Healthcare M E DICAL Alnylam makes your healthcare decision easier by providing a single comprehensive PPO medical and drug coverage plan through Blue Cross Blue Shield of Massachusetts. We offer three premium tiers: Employee Only, Employee Plus One Dependent, and Family. In addition, Alnylam pays for 85% of the plan premiums. FLEXIBLE SPENDING ACCOUNTS You have the option to redirect a portion of your pre-tax pay, through payroll deduction, into Flexible Spending Accounts (FSAs) to help pay for out of pocket medical expenses such as copayments, deductibles, some drugs, and some other health care costs. Alnylam offers a Healthcare FSA and a Dependent Care FSA through Discovery Benefits. DENTAL Alnylam offers a comprehensive dental plan through Delta Dental. The Delta Dental PPO Premier Plus plan provides you with access to two of Delta Dental s extensive national networks Delta Dental PPO, with more than 207,000 participating dentist locations and Delta Dental Premier, the largest dental network in the country with more than 290,000 dentist locations. Three out of four dentists nationwide participate in one or both of these networks. VISION Alnylam offers a single, comprehensive vision plan through Eye Med. This plan allows you to choose from independent doctors and retail providers, including LensCrafters, Pearle Vision, Sears Optical, Target Optical and JCPenney Optical. LIFE/DISABILITY Alnylam provides employees with company-paid Life and Accidental Death and Dismemberment (AD&D) insurance through Prudential. In addition, employees have the opportunity to purchase supplemental term life insurance for themselves, their spouse and their children. Alnylam provides a short-term disability (STD) paid leave if you have been disabled due to a non-occupational injury or illness. In addition, Alnylam provides a long-term disability (LTD) paid leave that provides disability benefits extending beyond the 12 weeks of STD. Both STD and LTD are company-paid benefits and offered through Prudential.

Work/Life TUITION REIMBURSEMENT Alnylam offers tuition assistance to support eligible employees in their pursuit of undergraduate or post-graduate level studies that are related to the employee s current role, or are part of a job-related degree or certificate program. Full-time employees will be reimbursed for tuition, books and required fees for pre-approved courses up to a set maximum. TRANSPORTATION PROGRAM Employees may take advantage of one of three transportation options: A company-paid monthly T Pass that allows for roundtrip subway and/or rail transit between the T stop located nearest to your home address and the Kendall Square T stop. Company-subsidized parking privileges for one vehicle within the company designated parking facility. A monthly benefit of $20.00/month, added directly to your semimonthly pay, if you bike or walk to work. EMPLOYEE ASSISTANCE PROGRAM (EAP) Kathleen Greer Associates provides professional and confidential counseling 24 hours a day, 7 days a week to individual employees and their household members. PET INSURANCE Nationwide pet insurance provides coverage for veterinary expenses related to accidents and illnesses. Policies available for dogs, cats, birds, and other exotic pets. FITNESS BENEFIT Alnylam has partnered with Cambridge Athletic Club, BodyScapes Fitness and Boston Sports Club to provide discounts on membership rates and enrollment fees. Alternatively, Alnylam will contribute towards the monthly membership rate of other fitness centers. CIRCLES CONCIERGE Alnylam offers Circles Concierge, a personal assistance service, at no cost to regular employees working an average of 30 or more hours per week. From product research to contractor referrals to personal travel arrangements, Circles can help make your life easier. EMPLOYEE DISCOUNTS Alnylam partners with a number of vendors and service providers to bring employees a number of discounts, including: Tickets@Work Columbia Insurance Agency Computer and technology purchases from Dell and CDW Cell phone service from AT&T and Verizon Kindercare Childcare Hubway Bike Share Program Local restaurants And many more!

Savings 401(K) PLAN Alnylam offers you the opportunity to participate in a 401(k) Savings Plan through Fidelity Investments in order to help save for retirement or other longer-term financial needs. Both full-time and part-time employees, age 18 or older, are eligible to participate. Through automatic payroll deductions, you may contribute up to 15% of your pre-tax earnings or a maximum of $18,000 per year for 2017 ($24,000 for employees age 50 or over) to the Alnylam 401(k) Savings Plan. EMPLOYEE STOCK PURCHASE PLAN The Employee Stock Purchase Plan (ESPP) provides all eligible U.S. based employees the opportunity to purchase shares of Alnylam common stock at a discount through payroll deductions. You may choose to withhold up to 15% of your base salary to purchase Alnylam common stock at eighty-five (85%) of the lower of 1) the fair market value per share of common stock on your Entry Date into the offering period or 2) the fair market value per share on the semi-annual purchase date. Alnylam offers a discretionary 401(k) match of up to 50% of the first 6% of employee contributions to a maximum of $8,000. The company match is in the form of Alnylam stock. STOCK OPTION PLAN The company has reserved a designated number of shares of its common stock for issuance to employees under the Alnylam Pharmaceuticals, Inc. 2009 Incentive Stock Plan. More details are available upon employment.

Paid Time Off VACATION TIME Alnylam provides eligible full-time employees with vacation time that accrues at the end of each month based on your length of service with Alnylam. 0-5 YEARS 5+ YEARS 15 days per year 20 days per year Part-time employees scheduled to work over 20 hours per week will accrue prorated vacation time at the end of each month. Employees may rollover up to 5 days (40 hours) of vacation time each year. FLEX DAYS Full-time employees are eligible for 3 additional flex days that can be used at any point in the year. SICK TIME Regular full-time employees are eligible for up to 5 days per year. Part-time employees scheduled to work over 20 hours per week will be eligible for sick time on a pro-rated basis. NEW YEAR S RECHARGE Alnylam closes down during the holiday week between Christmas and New Year s to allow employees to recharge and enjoy time with friends and family. HOLIDAY TIME Alnylam provides the following holidays for the 2018 calendar year. 2018 HOLIDAY DATE OBSERVED New Year s Day Martin Luther King Jr. Birthday Presidents Day Memorial Day Independence Day Labor Day Thanksgiving Day Day after Thanksgiving Christmas Eve Christmas Day Monday, January 1st Monday, January 15th Monday, February 19th Monday, May 28th Wednesday, July 4th Monday, September 3rd Thursday, November 22nd Friday, November 23rd Monday, December 24th Tuesday, December 25th New Year s Recharge Wednesday, December 26th - Monday, December 31st