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Filed pursuant to Rule 497 File Nos. 333-28339 and 811-08239 PROFUNDS ProFund VP Bull, ProFund VP Mid-Cap, ProFund VP Small-Cap, ProFund VP Dow 30, ProFund VP NASDAQ-100, ProFund VP Large-Cap Value, ProFund VP Large-Cap Growth, ProFund VP Mid-Cap Value, ProFund VP Mid-Cap Growth, ProFund VP Small-Cap Value, ProFund VP Small-Cap Growth, ProFund VP UltraBull, ProFund VP UltraMid- Cap, ProFund VP UltraSmall-Cap, ProFund VP UltraNASDAQ-100, ProFund VP Bear, ProFund VP Short Mid-Cap, ProFund VP Short Small-Cap, ProFund VP Short Dow 30, ProFund VP Short NASDAQ-100, ProFund VP UltraShort Dow 30, ProFund VP UltraShort NASDAQ-100, ProFund VP Banks, ProFund VP Basic Materials, ProFund VP Biotechnology, ProFund VP Consumer Goods, ProFund VP Consumer Services, ProFund VP Financials, ProFund VP Health Care, ProFund VP Industrials, ProFund VP Internet, ProFund VP Oil & Gas, ProFund VP Pharmaceuticals, ProFund VP Precious Metals, ProFund VP Real Estate, ProFund VP Semiconductor, ProFund VP Technology, ProFund VP Telecommunications and ProFund VP Utilities (together, the Funds ) Supplement dated October 1, 2013 to the Funds Summary Prospectuses dated May 1, 2013 and Statutory Prospectus dated May 1, 2013 (together, the Prospectuses ) and to the Funds Statement of Additional Information dated May 1, 2013 (the SAI ) Effective on October 1, 2013, the Prospectuses and the SAI are revised as follows: 1. For the Funds listed below, the following sentence replaces the last sentence in the section entitled Management in the Prospectuses: ProFund VP Bull, ProFund VP Mid-Cap, ProFund VP Small-Cap, ProFund VP Dow 30, ProFund VP NASDAQ-100, ProFund VP Large-Cap Value, ProFund VP Large-Cap Growth, ProFund VP Mid-Cap Value, ProFund VP Mid-Cap Growth, ProFund VP Small-Cap Value, ProFund VP Small-Cap Growth, ProFund VP UltraBull, ProFund VP UltraMid-Cap, ProFund VP UltraSmall-Cap, ProFund VP UltraNASDAQ-100, ProFund VP Bear, ProFund VP Short Mid-Cap, ProFund VP Short Small-Cap, ProFund VP Short Dow 30, ProFund VP Short NASDAQ-100, ProFund VP UltraShort Dow 30 and ProFund VP UltraShort NASDAQ-100: Michael Neches, Senior Portfolio Manager, and Rachel Ames, Portfolio Manager, have managed the Fund since October 2013. 2. For the Funds listed below, the following sentence replaces the last sentence in the section entitled Management in the Prospectuses: ProFund VP Banks, ProFund VP Basic Materials, ProFund VP Biotechnology, ProFund VP Consumer Goods, ProFund VP Consumer Services, ProFund VP Financials, ProFund VP Health Care, ProFund VP Industrials, ProFund VP Internet, ProFund VP Oil & Gas, ProFund VP Pharmaceuticals, ProFund VP Precious Metals, ProFund VP Real Estate, ProFund VP Semiconductor, ProFund VP Technology, ProFund VP Telecommunications and ProFund VP Utilities: Michael Neches, Senior Portfolio Manager, and Charles Lowery, Portfolio Manager, have managed the Fund since October 2013.

3. In the Statutory Prospectus, the fourth paragraph in the section entitled Portfolio Management is replaced in its entirety by the following paragraphs: Michael Neches, ProShare Advisors: Senior Portfolio Manager since November 2010 and Associate Portfolio Manager from January 2007 through October 2010. ProShare Capital Management LLC: Senior Portfolio Manager from June 2012 through September 2013. Rachel Ames, ProShare Advisors: Portfolio Manager since October 2013 and Associate Portfolio Manager from June 2009 through September 2013 and Portfolio Analyst from June 2004 through May 2009. ProFund Advisors LLC: Portfolio Manager since October 2013 and Associate Portfolio Manager from June 2009 through September 2013 and Portfolio Analyst from June 2004 through May 2009. Charles Lowery, ProShare Advisors: Portfolio Manager since October 2013 and Associate Portfolio Manager from July 2010 through September 2013 and Portfolio Analyst from October 2006 through June 2010. ProFund Advisors LLC: Portfolio Manager since October 2013 and Associate Portfolio Manager from July 2010 through September 2013 and Portfolio Analyst from October 2006 through June 2010. 4. The portfolio managers information in the section entitled Other Accounts Managed by Portfolio Managers of the SAI is replaced in its entirety with the following: Other Accounts Managed by Portfolio Managers Portfolio managers are generally responsible for multiple investment company accounts. As further described below, certain inherent conflicts of interest arise from the fact that portfolio managers have responsibility for multiple accounts, including conflicts relating to the allocation of investment opportunities. Listed below for each portfolio manager are the number and type of accounts managed or overseen by each team on which each portfolio manager acts, as of December 31, 2012 or as otherwise noted. Name of Portfolio Manager Number of All Registered Investment Companies Managed/Total Assets 1 Number of All Other Pooled Investment Vehicles Managed/Total Assets 2 Number of All Other Accounts Managed/Total Assets 3 Rachel Ames 0 4 $0 4 0 4 $0 4 0 4 $0 4 Alexander Ilyasov 38 $1,103,756,328 0 $0 0 $0 Michelle Liu 19 $5,039,252,166 0 $0 0 $0 Charles Lowery 0 4 $0 4 0 4 $0 4 0 4 $0 4 Michael Neches 0 4 $0 4 10 4 $1,542,368,183 4 0 4 $0 4 Jeffrey Ploshnick 10 $293,158,932 7 $956,121,437 0 $0 1 Includes assets of publicly available ProFunds, publicly available series of Access One Trust, and publicly available series of ProShares Trust. 2 Includes assets of series of ProShares Trust II. 3 Includes sub-advised registered investment companies and exchange-traded funds. 4 As of July 31, 2013. **Money Market funds not included** Listed below for each portfolio manager is a dollar range of securities beneficially owned in the Funds managed by the portfolio manager, together with the aggregate dollar range of equity securities in all registered investment companies in the Fund Complex, as of January 31, 2013 or as otherwise noted.

Name of Portfolio Manager Dollar Range of Equity Securities in the Funds Managed by the Portfolio Manager Aggregate Dollar Range of Equity Securities in All Registered Investment Companies in the ProFunds Family Rachel Ames None 1 None 1 Alexander Ilyasov None None Charles Lowery None 1 None 1 Michelle Liu None None Michael Neches None 1 None 1 Jeffrey Ploshnick None $1 - $10,000 1 As of May 31, 2013. Please retain this Supplement for future reference.

CLASSIC PROFUNDS VP Bull Mid-Cap Small-Cap Dow 30 NASDAQ-100 Large-Cap Value Large-Cap Growth Mid-Cap Value Mid-Cap Growth Small-Cap Value Small-Cap Growth Asia 30 Europe 30 International Emerging Markets Japan ULTRA PROFUNDS VP UltraBull UltraMid-Cap UltraSmall-Cap UltraNASDAQ-100 INVERSE PROFUNDS VP Bear Short Mid-Cap Short Small-Cap Short Dow 30 Short NASDAQ-100 Short International Short Emerging Markets UltraShort Dow 30 UltraShort NASDAQ-100 SECTOR PROFUNDS VP Banks Basic Materials Biotechnology Consumer Goods Consumer Services Financials Health Care Industrials Internet Oil & Gas Pharmaceuticals Precious Metals Real Estate Semiconductor Technology Telecommunications Utilities NON-EQUITY PROFUNDS VP U.S. Government Plus Rising Rates Opportunity Falling U.S. Dollar PROFUND VP MONEY MARKET Prospectus MAY 1, 2013 Like shares of all mutual funds, these securities have not been approved or disapproved by the Securities and Exchange Commission nor has the Securities and Exchange Commission passed upon the accuracy or adequacy of this Prospectus. Any representation to the contrary is a criminal offense.

Table of Contents 3 Summary Section CLASSIC PROFUNDS VP 4 Bull 7 Mid-Cap 11 Small-Cap 15 Dow 30 19 NASDAQ-100 23 Large-Cap Value 26 Large-Cap Growth 29 Mid-Cap Value 32 Mid-Cap Growth 35 Small-Cap Value 38 Small-Cap Growth 41 Asia 30 44 Europe 30 47 International 52 Emerging Markets 56 Japan ULTRA PROFUNDS VP 60 UltraBull 65 UltraMid-Cap 70 UltraSmall-Cap 75 UltraNASDAQ-100 INVERSE PROFUNDS VP 80 Bear 85 Short Mid-Cap 90 Short Small-Cap 95 Short Dow 30 100 Short NASDAQ-100 105 Short International 111 Short Emerging Markets 117 UltraShort Dow 30 122 UltraShort NASDAQ-100 SECTOR PROFUNDS VP 127 Banks 130 Basic Materials 133 Biotechnology 136 Consumer Goods 139 Consumer Services 142 Financials 145 Health Care 148 Industrials 151 Internet 154 Oil&Gas 157 Pharmaceuticals 160 Precious Metals 164 Real Estate 167 Semiconductor 170 Technology 173 Telecommunications 176 Utilities NON-EQUITY PROFUNDS VP 179 U.S. Government Plus 184 Rising Rates Opportunity 189 Falling U.S. Dollar 193 ProFund VP Money Market 197 ProFunds VP Investment Objectives, Principal Investment Strategies, Related Risks and Disclosure of Portfolio Holdings 213 ProFunds Management 217 General ProFunds VP Information 223 Financial Highlights This Prospectus should be read in conjunction with the offering documents of the separate account or insurance contract through which you invest in the ProFunds VP. This Prospectus may include information pertaining to certain portfolios that are not available through the separate account or insurance contract that you have chosen. Please refer to your variable annuity or life prospectus or offering documents to determine which portfolios are available to you and read and retain these documents for future reference.

Summary Section 3

4 :: ProFund VP Bull Investment Objective ProFund VP Bull (the Fund ) seeks investment results, before fees and expenses, that correspond to the performance of the S&P 500 (the Index ). Fees and Expenses of the Fund The table below describes the fees and expenses that you may pay if you buy or hold shares of the Fund. The expenses shown do not reflect charges or fees associated with insurance company separate accounts or insurance contracts, which would have the effect of increasing overall expenses. Annuity and policy holders should consult the prospectus for their contract or policy for more information about such charges and fees. Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment) Investment Advisory Fees 0.75% Distribution and Service (12b-1) Fees 0.25% Other Expenses 0.84% Total Annual Fund Operating Expenses Before Fee Waivers and Expense Reimbursements 1.84% Fee Waivers/Reimbursements* -0.16% Total Annual Fund Operating Expenses After Fee Waivers and Expense Reimbursements 1.68% * ProFund Advisors LLC ( ProFund Advisors or the Advisor ) has contractually agreed to waive Investment Advisory and Management Services Fees and to reimburse Other Expenses to the extent Total Annual Fund Operating Expenses Before Fee Waivers and Expense Reimbursements, as a percentage of average daily net assets, exceed 1.68% through April 30, 2014. After such date, the expense limitation may be terminated or revised. Amounts waived or reimbursed in a particular contractual period may be recouped by ProFund Advisors within three years of the end of that contractual period to the extent that recoupment will not cause the Fund s expenses to exceed any expense limitation in place at that time. Example: This example is intended to help you compare the cost of investing in the Fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the Fund for the time periods indicated and then redeem all of your shares at the end of each period. The example also assumes that your investment has a 5% return each year and that the Fund s operating expenses remain the same, except that the fee waiver/expense reimbursement is assumed only to pertain to the first year. It does not reflect separate account or insurance contract fees or charges. If these charges were reflected, expenses would be higher. Although your actual cost may be higher or lower, based on these assumptions your approximate costs would be: 1 Year 3 Years 5 Years 10 Years ProFund VP Bull $171 $563 $981 $2,145 The Fund pays transaction and financing costs associated with transacting in securities and derivatives. These costs are not reflected in the example or the table above. Portfolio Turnover The Fund pays transaction costs, such as commissions, when it buys and sells securities (or turns over its portfolio). A higher portfolio turnover may indicate higher transaction costs. These costs, which are not reflected in Annual Fund Operating Expenses or in the example above, affect the Fund s performance. During the most recent fiscal year, the Fund s annual portfolio turnover rate was 35% of the average value of its entire portfolio. This portfolio turnover rate is calculated without regard to cash instrument or derivatives transactions. If such transactions were included, the Fund s portfolio turnover rate would be significantly higher. Principal Investment Strategies The Fund invests in securities and derivatives that ProFund Advisors believes, in combination, should have similar return characteristics as the return of the Index. The Index is a measure of large-cap U.S. stock market performance. It is a float-adjusted, market capitalization weighted index of 500 U.S. operating companies and real estate investment trusts selected through a mechanical process that factors in criteria such as liquidity, price, market capitalization and financial viability. As of January 31, 2013, the Index included companies with capitalizations between $1.8 billion and $427.7 billion. The average capitalization of the companies comprising the Index was approximately $28.3 billion. The Index is published under the Bloomberg ticker symbol SPX. The types of securities and derivatives that the Fund will principally invest in are set forth below. Cash balances arising from the use of derivatives will typically be held in money market instruments. > Equity Securities The Fund invests in common stock issued by public companies. > Derivatives The Fund invests in derivatives, which are financial instruments whose value is derived from the value of an underlying asset (including ETFs), interest rate or index. The Fund invests in derivatives as a substitute for investing directly in stocks in order to gain exposure to the Index. These derivatives principally include: Swap Agreements Contracts entered into primarily with major global financial institutions for a specified period ranging from a day to more than one year. In a standard swap transaction, two parties agree to exchange the return (or differentials in rates of return) earned or realized on particular predetermined investments or instruments. The gross return to be exchanged or swapped between the parties is calculated with respect to a notional amount, e.g., the return on or change in value of a particular dollar amount invested in a basket of securities representing a particular index. Futures Contracts A standardized contract traded on, or subject to the rules of, an exchange that calls for the future delivery of a specified quantity and type of asset at a specified time and place or, alternatively, may call for cash settlement. > Money Market Instruments The Fund invests in shortterm cash instruments that have a remaining maturity of 397 days or less and exhibit high quality credit profiles, including: U.S. Treasury Bills U.S. government securities that have initial maturities of one year or less, and are supported by the full faith and credit of the United States. Repurchase Agreements Contracts in which a seller of securities, usually U.S. government securities or other money market instruments, agrees to buy them back at a specified time and price. Repurchase agreements are primarily used by the Fund as a short-term investment vehicle for cash positions. ProFund Advisors uses a mathematical approach to investing. Using this approach, ProFund Advisors determines the type,

FUND NUMBER :: 204 :: ProFund VP Bull :: 5 quantity and mix of investment positions that the Fund should hold to approximate the performance of the Index. The Fund may gain exposure to only a representative sample of the securities in the Index or may invest in securities or financial instruments not contained in the Index, with the intent of obtaining exposure to securities or financial instruments with aggregate characteristics similar to those of the Index. ProFund Advisors does not invest the assets of the Fund in securities or financial instruments based on ProFund Advisors view of the investment merit of a particular security, instrument, or company, other than for cash management purposes, nor does it conduct conventional research or analysis (other than in determining counterparty creditworthiness), or forecast market movement or trends, in managing the assets of the Fund. The Fund seeks to remain fully invested at all times in securities and/or financial instruments that, in combination, provide exposure to the Index without regard to market conditions, trends or direction. The Fund will concentrate its investments in a particular industry or group of industries to approximately the same extent as the Index is so concentrated. Please see Investment Objectives, Principal Investment Strategies and Related Risks in the Fund s full Prospectus for additional details. Principal Risks You could lose money by investing in the Fund. Risks Associated with the Use of Derivatives The Fund uses investment techniques, such as investing in derivatives, that may be considered aggressive. Investing in derivatives may expose the Fund to greater risks than investing directly in the reference asset(s) underlying those derivatives, such as counterparty risk, liquidity risk and increased correlation risk (each as discussed below). When the Fund uses derivatives, there may be imperfect correlation between the value of the reference asset(s) and the derivative, which may prevent the Fund from achieving its investment objective. The Fund may use a combination of swaps on an underlying index and swaps on an ETF that is designed to track the performance of that index. The performance of an ETF may not track the performance of its underlying index due to embedded costs and other factors. Thus, to the extent the Fund invests in swaps that use an ETF as the reference asset, the Fund may be subject to greater correlation risk and may not achieve as high a degree of correlation with its index as it would if the Fund only used swaps on the underlying index. Moreover, with respect to the use of swap agreements, if the Index has a dramatic intraday move that causes a material decline in the Fund s net assets, the terms of a swap agreement between the Fund and its counterparty may permit the counterparty to immediately close out the transaction with the Fund. In that event, the Fund may be unable to enter into another swap agreement or invest in other derivatives to achieve the desired exposure consistent with the Fund s investment objective. This, in turn, may prevent the Fund from achieving its investment objective, even if the Index reverses all or a portion of its intraday move by the end of the day. Any financing, borrowing and other costs associated with using derivatives may also have the effect of lowering the Fund s return. Active Investor Risk The Fund permits short-term trading of its securities. A significant portion of assets invested in the Fund come from professional money managers and investors who use the Fund as part of active trading or tactical asset allocation strategies. These strategies often call for frequent trading to take advantage of anticipated changes in market conditions, which could increase portfolio turnover and may result in additional costs for the Fund. In addition, large movements of assets into and out of the Fund may have a negative impact on the Fund s ability to achieve its investment objective or maintain a consistent level of operating expenses. In certain circumstances, the Fund s expense ratio may vary from current estimates or the historical ratio disclosed in this Prospectus. Correlation Risk A number of factors may affect the Fund s ability to achieve a high degree of correlation with the Index, and there can be no guarantee that the Fund will achieve a high degree of correlation. Failure to achieve a high degree of correlation may prevent the Fund from achieving its investment objective. The factors that may adversely affect the Fund s correlation with the Index include fees, expenses, transaction costs, financing costs associated with the use of derivatives, income items, valuation methodology, accounting standards and disruptions or illiquidity in the markets for the securities or financial instruments in which the Fund invests. The Fund may not have investment exposure to all securities in the Index, or its weighting of investment exposure to such securities may be different from that of the Index. In addition, the Fund may invest in securities or financial instruments not included in the Index. The Fund may also be subject to large movements of assets into and out of the Fund, potentially resulting in the Fund being over- or under-exposed to the Index. Activities surrounding Index reconstitutions or other Index rebalancing events may hinder the Fund s ability to meet its investment objective. Counterparty Risk The Fund will be subject to credit risk (i.e., the risk that a counterparty is unwilling or unable to make timely payments to meet its contractual obligations) with respect to the amount it expects to receive from counterparties to derivatives and repurchase agreements entered into by the Fund. If a counterparty becomes bankrupt or fails to perform its obligations, the value of your investment in the Fund may decline. Early Close/Late Close/Trading Halt Risk An exchange or market may close early, close late or issue trading halts on specific securities, or the ability to buy or sell certain securities or financial instruments may be restricted, which may result in the Fund being unable to buy or sell certain securities or financial instruments. In such circumstances, the Fund may be unable to rebalance its portfolio, may be unable to accurately price its investments and/or may incur substantial trading losses. Equity and Market Risk The equity markets are volatile, and the value of securities, swaps, futures and other instruments correlated with the equity markets may fluctuate dramatically from day-to-day. Equity markets are subject to political, regulatory, market and economic developments, as well as developments that impact specific economic sectors, industries or segments of the market. Volatility in the markets and/or market developments may cause the value of an investment in the Fund to decrease. Liquidity Risk In certain circumstances, such as the disruption of the orderly markets for the securities or financial instruments in which the Fund invests, the Fund might not be able to acquire or dispose of certain holdings quickly or at prices that represent true market value in the judgment of ProFund Advisors. Markets for the securities or financial instruments in which the Fund invests may be disrupted by a number of events, including but not limited to economic crises, natural disasters, new legislation, or regulatory changes inside or outside of the U.S. For example, regulation

6 :: ProFund VP Bull limiting the ability of certain financial institutions to invest in certain securities would likely reduce the liquidity of those securities. Such situations may prevent the Fund from limiting losses, realizing gains or achieving a high correlation with the Index. Non-Diversification Risk The Fund is classified as nondiversified under the Investment Company Act of 1940, and has the ability to invest a relatively high percentage of its assets in the securities of a small number of issuers susceptible to a single economic, political or regulatory event, or in financial instruments with a single counterparty if ProFund Advisors determines that doing so is the most efficient means of meeting the Fund s investment objective. This makes the performance of the Fund more susceptible to adverse impact to an issuer or counterparty than a diversified fund might be. This risk may be particularly acute if the Index is comprised of a small number of securities. Portfolio Turnover Risk The Fund s strategy typically involves high portfolio turnover to manage the Fund s investment exposure. Additionally, active trading of the Fund s shares may cause more frequent purchase and sales activities that could, in certain circumstances, increase the number of portfolio transactions. High levels of transactions increase brokerage costs and may result in increased taxable capital gains. Please see Investment Objectives, Principal Investment Strategies and Related Risks in the Fund s full Prospectus for additional details. Investment Results The bar chart below shows how the Fund s investment results have varied from year to year, and the table shows how the Fund s average annual total returns for various periods compare with a broad measure of market performance. This information provides some indication of the risks of investing in the Fund. It does not reflect charges and fees associated with a separate account that invests in the Fund or any insurance contract for which it is an investment option. Charges and fees will reduce returns. Past results are not predictive of future results. Annual Returns as of December 31 each year 30% 20% 10% 0% -10% -20% 25.59% 8.83% 2.74% 13.66% 3.55% 24.34% 12.58% -30% -37.67% -40% 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 0.00% 13.89% Average Annual Total Returns as of December 31, 2012 One Year Five Years Ten Years Inception Date ProFund VP Bull 13.89% -0.13% 5.09% 05/01/01 S&P 500 # 16.00% 1.66% 7.10% # Reflects no deduction for fees, expenses or taxes. Adjusted to reflect the reinvestment of dividends paid by companies in the Index. Management The Fund is advised by ProFund Advisors. Hratch Najarian, Senior Portfolio Manager, has managed the Fund since October 2010. Purchase and Sale of Fund Shares Shares are available for purchase by insurance company separate accounts to serve as an investment medium for variable insurance contracts, and by qualified pension and retirement plans, certain insurance companies, and ProFund Advisors. Investors do not contact the Fund directly to purchase or redeem shares. Please refer to the prospectus of the relevant separate account for information on the allocation of premiums and on transfers of accumulated value among sub-accounts of the separate accounts that invest in the Fund. Tax Information The Fund normally distributes its net investment income and net realized capital gains, if any, to its shareholders. If you are a holder of a contract or policy that invests in the Fund through an insurance company separate account, then these distributions may not be taxable to you; please consult the prospectus or other information provided to you by the insurance company regarding the tax consequences of your contract or policy. If you are investing through a pension or retirement plan that is a tax-deferred arrangement, you may be taxed later upon withdrawal of monies from those arrangements. Payments to Insurance Companies and Other Financial Intermediaries The Fund or its distributor (and related companies) may pay insurance companies, which in turn may pay broker-dealers or other financial intermediaries (such as banks and insurance companies, or their related companies) for the sale and retention of variable contracts and/or policies which offer Fund shares. These payments may create a conflict of interest for a financial intermediary selling such variable contracts and/or policies, or be a factor in the insurance company s decision to include the Fund as an investment option in its variable contract or policy. For more information, ask your financial advisor, visit your financial intermediary s website or consult the prospectus for the contract or policy. Best Quarter (ended 06/30/2009): 15.34%; Worst Quarter (ended 12/31/2008): -22.35%.

FUND NUMBER :: 241 :: ProFund VP Mid-Cap :: 7 Investment Objective ProFund VP Mid-Cap (the Fund ) seeks investment results, before fees and expenses, that correspond to the performance of the S&P MidCap 400 (the Index ). Fees and Expenses of the Fund The table below describes the fees and expenses that you may pay if you buy or hold shares of the Fund. The expenses shown do not reflect charges or fees associated with insurance company separate accounts or insurance contracts, which would have the effect of increasing overall expenses. Annuity and policy holders should consult the prospectus for their contract or policy for more information about such charges and fees. Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment) Investment Advisory Fees 0.75% Distribution and Service (12b-1) Fees 0.25% Other Expenses 0.81% Total Annual Fund Operating Expenses Before Fee Waivers and Expense Reimbursements 1.81% Fee Waivers/Reimbursements* -0.13% Total Annual Fund Operating Expenses After Fee Waivers and Expense Reimbursements 1.68% * ProFund Advisors LLC ( ProFund Advisors or the Advisor ) has contractually agreed to waive Investment Advisory and Management Services Fees and to reimburse Other Expenses to the extent Total Annual Fund Operating Expenses Before Fee Waivers and Expense Reimbursements, as a percentage of average daily net assets, exceed 1.68% through April 30, 2014. After such date, the expense limitation may be terminated or revised. Amounts waived or reimbursed in a particular contractual period may be recouped by ProFund Advisors within three years of the end of that contractual period to the extent that recoupment will not cause the Fund s expenses to exceed any expense limitation in place at that time. Example: This example is intended to help you compare the cost of investing in the Fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the Fund for the time periods indicated and then redeem all of your shares at the end of each period. The example also assumes that your investment has a 5% return each year and that the Fund s operating expenses remain the same, except that the fee waiver/expense reimbursement is assumed only to pertain to the first year. It does not reflect separate account or insurance contract fees or charges. If these charges were reflected, expenses would be higher. Although your actual cost may be higher or lower, based on these assumptions your approximate costs would be: 1 Year 3 Years 5 Years 10 Years ProFund VP Mid-Cap $171 $557 $968 $2,116 The Fund pays transaction and financing costs associated with transacting in securities and derivatives. These costs are not reflected in the example or the table above. Portfolio Turnover The Fund pays transaction costs, such as commissions, when it buys and sells securities (or turns over its portfolio). A higher portfolio turnover may indicate higher transaction costs. These costs, which are not reflected in Annual Fund Operating Expenses or in the example above, affect the Fund s performance. During the most recent fiscal year, the Fund s annual portfolio turnover rate was 0% of the average value of its entire portfolio. This portfolio turnover rate is calculated without regard to cash instrument or derivatives transactions. If such transactions were included, the Fund s portfolio turnover rate would be significantly higher. Principal Investment Strategies The Fund invests in securities and derivatives that ProFund Advisors believes, in combination, should have similar return characteristics as the return of the Index. The Index is a measure of mid-size company U.S. stock market performance. It is a floatadjusted, market capitalization weighted index of 400 U.S. operating companies and real estate investment trusts selected through a process that factors criteria such as liquidity, price, market capitalization and financial viability. As of January 31, 2013, the Index included companies with capitalizations between $473.8 million and $16.7 billion. The average capitalization of the companies comprising the Index was approximately $3.3 billion. The Index is published under the Bloomberg ticker symbol MID. The types of securities and derivatives that the Fund will principally invest in are set forth below. Cash balances arising from the use of derivatives will typically be held in money market instruments. > Derivatives The Fund invests in derivatives, which are financial instruments whose value is derived from the value of an underlying asset (including ETFs), interest rate or index. The Fund invests in derivatives as a substitute for investing directly in stocks in order to gain exposure to the Index. These derivatives principally include: Swap Agreements Contracts entered into primarily with major global financial institutions for a specified period ranging from a day to more than one year. In a standard swap transaction, two parties agree to exchange the return (or differentials in rates of return) earned or realized on particular predetermined investments or instruments. The gross return to be exchanged or swapped between the parties is calculated with respect to a notional amount, e.g., the return on or change in value of a particular dollar amount invested in a basket of securities representing a particular index. Futures Contracts A standardized contract traded on, or subject to the rules of, an exchange that calls for the future delivery of a specified quantity and type of asset at a specified time and place or, alternatively, may call for cash settlement. > Money Market Instruments The Fund invests in shortterm cash instruments that have a remaining maturity of 397 days or less and exhibit high quality credit profiles, including: U.S. Treasury Bills U.S. government securities that have initial maturities of one year or less, and are supported by the full faith and credit of the United States. Repurchase Agreements Contracts in which a seller of securities, usually U.S. government securities or other money market instruments, agrees to buy them back at a specified time and price. Repurchase agreements are primarily used by the Fund as a short-term investment vehicle for cash positions. ProFund Advisors uses a mathematical approach to investing. Using this approach, ProFund Advisors determines the type, quantity and mix of investment positions that the Fund should hold to approximate the performance of the Index. The Fund may gain exposure to only a representative sample of the securities in the Index or may invest in securities or financial instruments not

8 :: ProFund VP Mid-Cap contained in the Index, with the intent of obtaining exposure to securities or financial instruments with aggregate characteristics similar to those of the Index. ProFund Advisors does not invest the assets of the Fund in securities or financial instruments based on ProFund Advisors view of the investment merit of a particular security, instrument, or company, other than for cash management purposes, nor does it conduct conventional research or analysis (other than in determining counterparty creditworthiness), or forecast market movement or trends, in managing the assets of the Fund. The Fund seeks to remain fully invested at all times in securities and/or financial instruments that, in combination, provide exposure to the Index without regard to market conditions, trends or direction. The Fund will concentrate its investments in a particular industry or group of industries to approximately the same extent as the Index is so concentrated. Please see Investment Objectives, Principal Investment Strategies and Related Risks in the Fund s full Prospectus for additional details. Principal Risks You could lose money by investing in the Fund. Risks Associated with the Use of Derivatives The Fund uses investment techniques, such as investing in derivatives, that may be considered aggressive. Investing in derivatives may expose the Fund to greater risks than investing directly in the reference asset(s) underlying those derivatives, such as counterparty risk, liquidity risk and increased correlation risk (each as discussed below). When the Fund uses derivatives, there may be imperfect correlation between the value of the reference asset(s) and the derivative, which may prevent the Fund from achieving its investment objective. The Fund may use a combination of swaps on an underlying index and swaps on an ETF that is designed to track the performance of that index. The performance of an ETF may not track the performance of its underlying index due to embedded costs and other factors. Thus, to the extent the Fund invests in swaps that use an ETF as the reference asset, the Fund may be subject to greater correlation risk and may not achieve as high a degree of correlation with its index as it would if the Fund only used swaps on the underlying index. Moreover, with respect to the use of swap agreements, if the Index has a dramatic intraday move that causes a material decline in the Fund s net assets, the terms of a swap agreement between the Fund and its counterparty may permit the counterparty to immediately close out the transaction with the Fund. In that event, the Fund may be unable to enter into another swap agreement or invest in other derivatives to achieve the desired exposure consistent with the Fund s investment objective. This, in turn, may prevent the Fund from achieving its investment objective, even if the Index reverses all or a portion of its intraday move by the end of the day. Any financing, borrowing and other costs associated with using derivatives may also have the effect of lowering the Fund s return. Active Investor Risk The Fund permits short-term trading of its securities. A significant portion of assets invested in the Fund come from professional money managers and investors who use the Fund as part of active trading or tactical asset allocation strategies. These strategies often call for frequent trading to take advantage of anticipated changes in market conditions, which could increase portfolio turnover and may result in additional costs for the Fund. In addition, large movements of assets into and out of the Fund may have a negative impact on the Fund s ability to achieve its investment objective or maintain a consistent level of operating expenses. In certain circumstances, the Fund s expense ratio may vary from current estimates or the historical ratio disclosed in this Prospectus. Correlation Risk A number of factors may affect the Fund s ability to achieve a high degree of correlation with the Index, and there can be no guarantee that the Fund will achieve a high degree of correlation. Failure to achieve a high degree of correlation may prevent the Fund from achieving its investment objective. The factors that may adversely affect the Fund s correlation with the Index include fees, expenses, transaction costs, financing costs associated with the use of derivatives, income items, valuation methodology, accounting standards and disruptions or illiquidity in the markets for the securities or financial instruments in which the Fund invests. The Fund may not have investment exposure to all securities in the Index, or its weighting of investment exposure to such securities may be different from that of the Index. In addition, the Fund may invest in securities or financial instruments not included in the Index. The Fund may also be subject to large movements of assets into and out of the Fund, potentially resulting in the Fund being over- or under-exposed to the Index. Activities surrounding Index reconstitutions or other Index rebalancing events may hinder the Fund s ability to meet its investment objective. Counterparty Risk The Fund will be subject to credit risk (i.e., the risk that a counterparty is unwilling or unable to make timely payments to meet its contractual obligations) with respect to the amount it expects to receive from counterparties to derivatives and repurchase agreements entered into by the Fund. If a counterparty becomes bankrupt or fails to perform its obligations, the value of your investment in the Fund may decline. Early Close/Late Close/Trading Halt Risk An exchange or market may close early, close late or issue trading halts on specific securities, or the ability to buy or sell certain securities or financial instruments may be restricted, which may result in the Fund being unable to buy or sell certain securities or financial instruments. In such circumstances, the Fund may be unable to rebalance its portfolio, may be unable to accurately price its investments and/or may incur substantial trading losses. Equity and Market Risk The equity markets are volatile, and the value of securities, swaps, futures and other instruments correlated with the equity markets may fluctuate dramatically from day-to-day. Equity markets are subject to political, regulatory, market and economic developments, as well as developments that impact specific economic sectors, industries or segments of the market. Volatility in the markets and/or market developments may cause the value of an investment in the Fund to decrease. Liquidity Risk In certain circumstances, such as the disruption of the orderly markets for the securities or financial instruments in which the Fund invests, the Fund might not be able to acquire or dispose of certain holdings quickly or at prices that represent true market value in the judgment of ProFund Advisors. Markets for the securities or financial instruments in which the Fund invests may be disrupted by a number of events, including but not limited to economic crises, natural disasters, new legislation, or regulatory changes inside or outside of the U.S. For example, regulation limiting the ability of certain financial institutions to invest in certain securities would likely reduce the liquidity of those securities. Such situations may prevent the Fund from limiting losses, realizing gains or achieving a high correlation with the Index.

FUND NUMBER :: 241 :: ProFund VP Mid-Cap :: 9 Non-Diversification Risk The Fund is classified as nondiversified under the Investment Company Act of 1940, and has the ability to invest a relatively high percentage of its assets in the securities of a small number of issuers susceptible to a single economic, political or regulatory event, or in financial instruments with a single counterparty if ProFund Advisors determines that doing so is the most efficient means of meeting the Fund s investment objective. This makes the performance of the Fund more susceptible to adverse impact to an issuer or counterparty than a diversified fund might be. This risk may be particularly acute if the Index is comprised of a small number of securities. Portfolio Turnover Risk The Fund s strategy typically involves high portfolio turnover to manage the Fund s investment exposure. Additionally, active trading of the Fund s shares may cause more frequent purchase and sales activities that could, in certain circumstances, increase the number of portfolio transactions. High levels of transactions increase brokerage costs and may result in increased taxable capital gains. Small- and Mid-Cap Company Investment Risk The Index and, by extension, the Fund are exposed to the risks posed by stocks of small- and mid-cap companies. The risk of equity investing may be particularly acute for securities of issuers with smaller market capitalizations. Small- and mid-cap company stocks may trade at greater spreads or lower trading volumes, and may be less liquid than the stocks of larger companies. Small- and mid-cap companies may have limited product lines or resources, may be dependent upon a particular market niche and may have greater fluctuations in price than the stocks of larger companies. Further, stocks of small- and mid-sized companies could be more difficult to liquidate during market downturns compared to larger, more widely traded companies. In addition, small- and mid-cap companies may lack the financial and personnel resources to handle economic or industry-wide setbacks and, as a result, such setbacks could have a greater effect on small- and mid-cap security prices. Please see Investment Objectives, Principal Investment Strategies and Related Risks in the Fund s full Prospectus for additional details. Investment Results The bar chart below shows how the Fund s investment results have varied from year to year, and the table shows how the Fund s average annual total returns for various periods compare with a broad measure of market performance. This information provides some indication of the risks of investing in the Fund. It does not reflect charges and fees associated with a separate account that invests in the Fund or any insurance contract for which it is an investment option. Charges and fees will reduce returns. Past results are not predictive of future results. Annual Returns as of December 31 each year 40% 30% 20% 10% 0% -10% -20% -30% -40% -38.37% 32.88% 24.05% -4.18% 15.54% 2008 2009 2010 2011 2012 Best Quarter (ended 09/30/2009): 19.16%; Worst Quarter (ended 12/31/2008): -26.38%. Average Annual Total Returns as of December 31, 2012 One Year Five Years Since Inception Inception Date ProFund VP Mid-Cap 15.54% 2.38% 2.04% 08/31/07 S&P MidCap 400 # 17.88% 5.15% 4.79% # Reflects no deduction for fees, expenses or taxes. Adjusted to reflect the reinvestment of dividends paid by companies in the Index. Since inception returns are calculated from the date the Fund commenced operations, not the date of inception of the Index. Management The Fund is advised by ProFund Advisors. Hratch Najarian, Senior Portfolio Manager, has managed the Fund since October 2010. Purchase and Sale of Fund Shares Shares are available for purchase by insurance company separate accounts to serve as an investment medium for variable insurance contracts, and by qualified pension and retirement plans, certain insurance companies, and ProFund Advisors. Investors do not contact the Fund directly to purchase or redeem shares. Please refer to the prospectus of the relevant separate account for information on the allocation of premiums and on transfers of accumulated value among sub-accounts of the separate accounts that invest in the Fund. Tax Information The Fund normally distributes its net investment income and net realized capital gains, if any, to its shareholders. If you are a holder of a contract or policy that invests in the Fund through an insurance company separate account, then these distributions may not be taxable to you; please consult the prospectus or other information provided to you by the insurance company regarding the tax consequences of your contract or policy. If you are investing through a pension or retirement plan that is a tax-deferred arrangement, you may be taxed later upon withdrawal of monies from those arrangements.

10 :: ProFund VP Mid-Cap Payments to Insurance Companies and Other Financial Intermediaries The Fund or its distributor (and related companies) may pay insurance companies, which in turn may pay broker-dealers or other financial intermediaries (such as banks and insurance companies, or their related companies) for the sale and retention of variable contracts and/or policies which offer Fund shares. These payments may create a conflict of interest for a financial intermediary selling such variable contracts and/or policies, or be a factor in the insurance company s decision to include the Fund as an investment option in its variable contract or policy. For more information, ask your financial advisor, visit your financial intermediary s website or consult the prospectus for the contract or policy.

FUND NUMBER :: 213 :: ProFund VP Small-Cap :: 11 Investment Objective The ProFund VP Small-Cap (the Fund ) seeks investment results, before fees and expenses, that correspond to the performance of the Russell 2000 Index (the Index ). Fees and Expenses of the Fund The table below describes the fees and expenses that you may pay if you buy or hold shares of the Fund. The expenses shown do not reflect charges or fees associated with insurance company separate accounts or insurance contracts, which would have the effect of increasing overall expenses. Annuity and policy holders should consult the prospectus for their contract or policy for more information about such charges and fees. Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment) Investment Advisory Fees 0.75% Distribution and Service (12b-1) Fees 0.25% Other Expenses 0.98% Acquired Fund Fees and Expenses* 0.01% Total Annual Fund Operating Expenses Before Fee Waivers and Expense Reimbursements 1.99% Fee Waivers/Reimbursements** -0.30% Total Annual Fund Operating Expenses After Fee Waivers and Expense Reimbursements 1.69% * Acquired Fund Fees and Expenses are not directly borne by the Fund and are not reflected in the Fund s Financial Statements. Therefore, the amounts listed in the Total Annual Fund Operating Expenses After Fee Waivers and Reimbursements will differ from those presented in the Fund s Financial Highlights. **ProFund Advisors LLC ( ProFund Advisors or the Advisor ) has contractually agreed to waive Investment Advisory and Management Services Fees and to reimburse Other Expenses to the extent Total Annual Fund Operating Expenses Before Fee Waivers and Expense Reimbursements (excluding Acquired Fund Fees and Expenses), as a percentage of average daily net assets, exceed 1.68% through April 30, 2014. After such date, the expense limitation may be terminated or revised. Amounts waived or reimbursed in a particular contractual period may be recouped by ProFund Advisors within three years of the end of that contractual period to the extent that recoupment will not cause the Fund s expenses to exceed any expense limitation in place at that time. Example: This example is intended to help you compare the cost of investing in the Fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the Fund for the time periods indicated and then redeem all of your shares at the end of each period. The example also assumes that your investment has a 5% return each year and that the Fund s operating expenses remain the same, except that the fee waiver/expense reimbursement is assumed only to pertain to the first year. It does not reflect separate account or insurance contract fees or charges. If these charges were reflected, expenses would be higher. Although your actual cost may be higher or lower, based on these assumptions your approximate costs would be: 1 Year 3 Years 5 Years 10 Years ProFund VP Small-Cap $172 $595 $1,045 $2,293 The Fund pays transaction and financing costs associated with transacting in securities and derivatives. These costs are not reflected in the example or the table above. Portfolio Turnover The Fund pays transaction costs, such as commissions, when it buys and sells securities (or turns over its portfolio). A higher portfolio turnover may indicate higher transaction costs. These costs, which are not reflected in Annual Fund Operating Expenses or in the example above, affect the Fund s performance. During the most recent fiscal year, the Fund s annual portfolio turnover rate was 29% of the average value of its entire portfolio. This portfolio turnover rate is calculated without regard to cash instrument or derivatives transactions. If such transactions were included, the Fund s portfolio turnover rate would be significantly higher. Principal Investment Strategies The Fund invests in securities and derivatives that ProFund Advisors believes, in combination, should have similar return characteristics as the return of the Index. The Index is a measure of small-cap U.S. stock market performance. It is a float-adjusted, market capitalization weighted index containing approximately 2000 of the smallest companies in the Russell 3000 Index, or approximately 8% of the total market capitalization of the Russell 3000 Index, which in turn represents approximately 98% of the investable U.S. equity market. As of January 31, 2013, the Index included companies with capitalizations between $43.0 million and $5.2 billion. The average capitalization of the companies comprising the Index was approximately $783.9 million. The Index is published under the Bloomberg ticker symbol RTY. The types of securities and derivatives that the Fund will principally invest in are set forth below. Cash balances arising from the use of derivatives will typically be held in money market instruments. > Equity Securities The Fund invests in common stock issued by public companies. > Derivatives The Fund invests in derivatives, which are financial instruments whose value is derived from the value of an underlying asset (including ETFs), interest rate or index. The Fund invests in derivatives as a substitute for investing directly in stocks in order to gain exposure to the Index. These derivatives principally include: Swap Agreements Contracts entered into primarily with major global financial institutions for a specified period ranging from a day to more than one year. In a standard swap transaction, two parties agree to exchange the return (or differentials in rates of return) earned or realized on particular predetermined investments or instruments. The gross return to be exchanged or swapped between the parties is calculated with respect to a notional amount, e.g., the return on or change in value of a particular dollar amount invested in a basket of securities representing a particular index. Futures Contracts A standardized contract traded on, or subject to the rules of, an exchange that calls for the future delivery of a specified quantity and type of asset at a specified time and place or, alternatively, may call for cash settlement. > Money Market Instruments The Fund invests in shortterm cash instruments that have a remaining maturity of 397 days or less and exhibit high quality credit profiles, including: U.S. Treasury Bills U.S. government securities that have initial maturities of one year or less, and are supported by the full faith and credit of the United States. Repurchase Agreements Contracts in which a seller of securities, usually U.S. government securities or other money