Virtus Seix Limited Duration Fund, a series of Virtus Asset Trust

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Virtus Seix Limited Duration Fund, a series of Virtus Asset Trust Supplement dated February 8, 2018 to the Prospectuses and Statement of Additional Information ( SAI ) dated June 23, 2017, as supplemented IMPORTANT NOTICE TO INVESTORS Effective February 7, 2018, the Virtus Seix Limited Duration Fund (the Fund ) was liquidated. The Fund has ceased to exist and is no longer available for sale. Accordingly, the Fund s Prospectuses and SAI are no longer valid. Investors should retain this supplement with the Prospectuses and SAI for future reference. VAT 8622/LtdDurClosed (2/2018)

Virtus Seix Limited Duration Fund, a series of Virtus Asset Trust Supplement dated February 1, 2018 to the Prospectuses and Statement of Additional Information ( SAI ) dated June 23, 2017, as supplemented IMPORTANT NOTICE TO INVESTORS The Board of Trustees of Virtus Asset Trust has approved the liquidation of Virtus Seix Limited Duration Fund (the Fund ). Based on the recommendation of management, the Trustees determined that liquidation is in the best interest of the shareholders and voted to direct the mandatory redemption of all shares of the Fund. As previously announced, effective January 26, 2018, the Fund was closed to new investors and additional investor deposits. On or about February 7, 2018 (the Liquidation Date ), the Fund will be liquidated at its net asset value. Prior to such time, shareholders may exchange their shares of the Fund for shares of the same class of any other Virtus Mutual Fund. Shareholders may also redeem their shares at any time prior to the Fund s liquidation on the Liquidation Date. There will be no fee or sales charges associated with exchange or redemption requests. Because the exchange or redemption of your shares could be a taxable event, we suggest that you consult with your tax advisor prior to the Fund s liquidation. Investors should retain this supplement with the Prospectuses and SAI for future reference. VAT 8622/LtdDurClosing (1/2018)

Virtus Seix Limited Duration Fund, a series of Virtus Asset Trust Supplement dated January 26, 2018 to the Prospectuses and Statement of Additional Information ( SAI ) dated June 23, 2017, as supplemented IMPORTANT NOTICE Availability of Fund Effective January 26, 2018, Virtus Seix Limited Duration Fund is not available for purchase by new or existing investors or for exchange from another Virtus Fund. Investors should retain this supplement for future reference. VAT 8622/VSLDFClosed (1/2018)

Virtus Asset Trust Supplement dated November 16, 2017 to the Statutory Prospectus dated June 23, 2017, as supplemented IMPORTANT NOTICE In the section Account Policies on page 212 of the Statutory Prospectus, the first bullet under Exchange Privileges is hereby replaced with the following: You may generally exchange shares of one fund for the same class of shares of another fund (e.g., Class A Shares for Class A Shares). Exchange privileges may not be available for all Virtus Mutual Funds and may be rejected or suspended. Investors should retain this supplement for future reference. VAT 8622/ExchPriv (11/2017)

Virtus Asset Trust Supplement dated July 17, 2017 to the Prospectuses and Statement of Additional Information ( SAI ) dated June 23, 2017 IMPORTANT NOTICE Availability of Shares Class T Shares are not currently available for purchase. Investors should retain this supplement for future reference. VAT 8622/ClassTNotAvailable (7/2017)

PROSPECTUS VIRTUS ASSET TRUST June 23, 2017, as supplemented September 18, 2017 TICKER SYMBOL BY CLASS FUND A C I R R6 T Virtus Ceredex Large-Cap Value Equity Fund SVIIX SVIFX STVTX STVZX VLTVX Virtus Ceredex Mid-Cap Value Equity Fund SAMVX SMVFX SMVTX SMVZX VCMVX Virtus Ceredex Small-Cap Value Equity Fund SASVX STCEX SCETX VTCSX Virtus Conservative Allocation Strategy Fund SVCAX SCCLX SCCTX VCATX Virtus Growth Allocation Strategy Fund SGIAX SGILX CLVGX VGATX Virtus Seix Core Bond Fund STGIX STIGX SCIGX STGZX STCBX Virtus Seix Corporate Bond Fund SAINX STIFX STICX VCTBX Virtus Seix Floating Rate High Income Fund SFRAX SFRCX SAMBX SFRZX SFRTX Virtus Seix Georgia Tax-Exempt Bond Fund SGTEX SGATX VTGBX Virtus Seix High Grade Municipal Bond Fund SFLTX SCFTX VTHMX Virtus Seix High Income Fund SAHIX STHTX STHIX STHZX VHITX Virtus Seix High Yield Fund HYPSX SAMHX HYLSX HYIZX VXHYX Virtus Seix Investment Grade Tax-Exempt Bond Fund SISIX STTBX VXTGX Virtus Seix Limited Duration Fund SAMLX VSDTX Virtus Seix North Carolina Tax-Exempt Bond Fund SNCIX CNCFX VNCTX Virtus Seix Short-Term Bond Fund STSBX SCBSX SSBTX VXSBX Virtus Seix Short-Term Municipal Bond Fund SMMAX CMDTX VMBTX Virtus Seix Total Return Bond Fund CBPSX SAMFX SCBLX SAMZX SAMTX Virtus Seix U.S. Government Securities Ultra-Short Bond Fund SIGVX SIGZX SUSTX Virtus Seix U.S. Mortgage Fund SLTMX SCLFX SLMTX VTUSX Virtus Seix Ultra-Short Bond Fund SISSX VUBTX Virtus Seix Virginia Intermediate Municipal Bond Fund CVIAX CRVTX VVBTX Virtus Silvant Large-Cap Growth Stock Fund STCIX STCFX STCAX STCZX VSLGX Virtus Silvant Small-Cap Growth Stock Fund SCGIX SSCFX SSCTX SCGTX Virtus WCM International Equity Fund SCIIX STITX SCIZX VXIEX Virtus Zevenbergen Innovative Growth Stock Fund SAGAX SCATX VTZIX Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense. This prospectus contains important information that you should know before investing in Virtus Mutual Funds. Please read it carefully and retain it for future reference. Not FDIC Insured No Bank Guarantee May Lose Value

Virtus Mutual Funds FUND SUMMARIES Virtus Ceredex Large-Cap Value Equity Fund... 1 Virtus Ceredex Mid-Cap Value Equity Fund... 6 Virtus Ceredex Small-Cap Value Equity Fund... 11 Virtus Conservative Allocation Strategy Fund... 16 Virtus Growth Allocation Strategy Fund... 22 VirtusSeixCoreBondFund... 28 VirtusSeixCorporateBondFund... 34 Virtus Seix Floating Rate High Income Fund... 39 Virtus Seix Georgia Tax-Exempt Bond Fund... 45 Virtus Seix High Grade Municipal Bond Fund... 50 Virtus Seix High Income Fund... 55 Virtus Seix High Yield Fund... 61 Virtus Seix Investment Grade Tax-Exempt Bond Fund... 67 Virtus Seix Limited Duration Fund... 72 Virtus Seix North Carolina Tax-Exempt Bond Fund... 77 VirtusSeixShort-TermBondFund... 82 Virtus Seix Short-Term Municipal Bond Fund... 87 Virtus Seix Total Return Bond Fund... 92 Virtus Seix U.S. Government Securities Ultra-Short Bond Fund... 98 Virtus Seix U.S. Mortgage Fund... 103 VirtusSeixUltra-ShortBondFund... 108 Virtus Seix Virginia Intermediate Municipal Bond Fund... 113 Virtus Silvant Large-Cap Growth Stock Fund... 118 Virtus Silvant Small-Cap Growth Stock Fund... 123 Virtus WCM International Equity Fund... 128 Virtus Zevenbergen Innovative Growth Stock Fund... 133 MORE INFORMATION ABOUT FUND EXPENSES... 138 MORE INFORMATION ABOUT INVESTMENT OBJECTIVES AND PRINCIPAL INVESTMENT STRATEGIES... 139 Virtus Ceredex Large-Cap Value Equity Fund... 140 Virtus Ceredex Mid-Cap Value Equity Fund... 141 Virtus Ceredex Small-Cap Value Equity Fund... 142 Virtus Conservative Allocation Strategy Fund... 143 Virtus Growth Allocation Strategy Fund... 144 VirtusSeixCoreBondFund... 145 VirtusSeixCorporateBondFund... 146 Virtus Seix Floating Rate High Income Fund... 148 Virtus Seix Georgia Tax-Exempt Bond Fund... 150 Virtus Seix High Grade Municipal Bond Fund... 151 Virtus Seix High Income Fund... 152 Virtus Seix High Yield Fund... 153 Virtus Seix Investment Grade Tax-Exempt Bond Fund... 154 Virtus Seix Limited Duration Fund... 155 Virtus Seix North Carolina Tax-Exempt Bond Fund... 156 VirtusSeixShort-TermBondFund... 157 Virtus Seix Short-Term Municipal Bond Fund... 158

FUND SUMMARIES Virtus Seix Total Return Bond Fund... 159 Virtus Seix U.S. Government Securities Ultra-Short Bond Fund... 161 Virtus Seix U.S. Mortgage Fund... 162 VirtusSeixUltra-ShortBondFund... 163 Virtus Seix Virginia Intermediate Municipal Bond Fund... 164 Virtus Silvant Large-Cap Growth Stock Fund... 165 Virtus Silvant Small-Cap Growth Stock Fund... 166 Virtus WCM International Equity Fund... 167 Virtus Zevenbergen Innovative Growth Stock Fund... 168 MORE INFORMATION ABOUT RISKS RELATED TO PRINCIPAL INVESTMENT STRATEGIES... 169 MANAGEMENT OF THE FUNDS... 181 RISKS ASSOCIATED WITH ADDITIONAL INVESTMENT TECHNIQUES AND FUND OPERATIONS... 190 PRICING OF FUND SHARES... 194 SALES CHARGES... 196 YOUR ACCOUNT... 205 HOW TO BUY SHARES... 207 HOW TO SELL SHARES... 209 THINGS YOU SHOULD KNOW WHEN SELLING SHARES... 210 ACCOUNT POLICIES... 212 INVESTOR SERVICES AND OTHER INFORMATION... 215 TAX STATUS OF DISTRIBUTIONS... 216 FINANCIAL HIGHLIGHTS... 219 APPENDIX A Intermediary Sales Charge Discounts and Waivers... 243

Virtus Ceredex Large-Cap Value Equity Fund Investment Objective The fund has an investment objective of seeking to provide a high level of capital appreciation. As a secondary goal, the fund also seeks to provide current income. Fees and Expenses The tables below illustrate the fees and expenses that you may pay if you buy and hold shares of the fund. You may qualify for sales charge discounts if you and your family invest, or agree to invest in the future, at least $50,000 in Virtus Funds. You may qualify for sales charge discounts in Class T Shares if you invest at least $250,000 in the fund. Information about these and other discounts is available: (i) from your financial advisor or other financial intermediary; (ii) under Sales Charges on page 196 of the fund s statutory prospectus; (iii) with respect to purchase of shares through specific intermediaries, in Appendix A to the fund s statutory prospectus, entitled Intermediary Sales Charge Discounts and Waivers; and (iv) under Alternative Purchase Arrangements on page 131 of the fund s statement of additional information. The Virtus Ceredex Large-Cap Value Equity Fund, a series of Virtus Asset Trust, is the successor of the RidgeWorth Ceredex Large Cap Value Equity Fund, a series of RidgeWorth Funds ( Predecessor Fund ), resulting from a reorganization of the Predecessor Fund with and into the fund. Shareholder Fees (fees paid directly from your investment) Class A Class C Class I Class R6 Class T Maximum Sales Charge (load) Imposed on Purchases (as a percentage of offering price) 5.75% None None None 2.50% Maximum Deferred Sales Charge (load) (as a percentage of the lesser of purchase price or redemption proceeds) None 1.00% (a) None None None Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment) Class A Class C Class I Class R6 Class T Management Fees 0.65% 0.65% 0.65% 0.65% 0.65% Distribution and Shareholder Servicing (12b-1) Fees 0.25% 1.00% None None 0.25% Other Expenses 0.40% (b) 0.21% (b) 0.42% (b) 0.20% (b) 0.40% (c) Acquired Fund Fees and Expenses 0.01% 0.01% 0.01% 0.01% 0.01% Total Annual Fund Operating Expenses 1.31% 1.87% 1.08% 0.86% 1.31% Less: Fee Waivers and/or Expense Reimbursements (d) -0.06% -0.14% -0.10% -0.13% -0.06% Total Annual Fund Operating Expenses After Fee Waivers and/or Expense Reimbursements (d) 1.25% 1.73% 0.98% 0.73% 1.25% (a) (b) (c) (d) The deferred sales charge is imposed on Class C Shares redeemed during the first year only. Restated to reflect current fees and expenses. Estimated for current fiscal year, as annualized. The fund s investment adviser has contractually agreed to limit the fund s total operating expenses (excluding front-end or contingent deferred loads, taxes, leverage expenses, interest, brokerage commissions, expenses incurred in connection with any merger or reorganization, unusual or infrequently occurring expenses (such as litigation) and acquired fund fees and expenses, if any) so that such expenses do not exceed 1.24% for Class A Shares, 1.72% for Class C Shares, 0.97% for Class I Shares, 0.72% for Class R6 Shares and 1.24% for Class T Shares through July 31, 2019. Following the contractual period, the adviser may discontinue these expense reimbursement arrangements at any time. Under certain conditions, the adviser may recapture operating expenses reimbursed under these arrangements for a period of three years following the date on which such reimbursement occurred. 1 Virtus Ceredex Large-Cap Value Equity Fund

Example This example is intended to help you compare the cost of investing in the fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the fund for the time periods indicated and then redeem all of your shares at the end of those periods. It shows your costs if you sold your shares at the end of the period or continued to hold them. The example also assumes that your investment has a 5% return each year, that the fund s operating expenses remain the same and that the expense reimbursement agreement remains in place for the contractual period. Although your actual costs may be higher or lower, based on these assumptions your costs would be: Share Status 1 Year 3 Years 5 Years 10 Years Class A Sold or Held $695 $955 $1,241 $2,053 Sold $276 $560 $ 984 $2,167 Class C Held $176 $560 $ 984 $2,167 Class I Sold or Held $100 $323 $ 576 $1,299 Class R6 Sold or Held $ 75 $248 $ 451 $1,036 Class T Sold or Held $374 $643 $ 939 $1,779 Portfolio Turnover The fund pays transaction costs, such as commissions, when it buys and sells securities (or turns over its portfolio). A higher portfolio turnover rate may indicate higher transaction costs and may result in higher taxes when fund shares are held in a taxable account. These costs, which are not reflected in annual fund operating expenses or in the example, affect the fund s performance. During the most recent fiscal year, the Predecessor Fund s portfolio turnover rate was 77% of the average value of its portfolio. Investments, Risks and Performance Principal Investment Strategies Under normal circumstances, the fund invests at least 80% of its net assets (plus any borrowings for investment purposes) in U.S.-traded equity securities of large-capitalization companies. U.S.-traded equity securities may include American Depositary Receipts ( ADRs ). The subadviser considers large-capitalization companies to be companies with market capitalizations generally within those of companies in the Russell 1000 Value Index. As of March 31, 2017, the market capitalization range of the companies in the Russell 1000 Value Index was $628.9 million to $755 billion. As a result of its investment strategy, the fund s portfolio turnover rate may be 100% or more and the fund may focus its investments in one or more sectors. In selecting investments for purchase and sale, the subadviser chooses companies that it believes are undervalued in the market relative to the industry sector and the company s own valuation history. The subadviser evaluates potential catalysts that may cause an upward re-rating of the stock s valuation. The common stocks purchased for the fund generally pay dividends at the time of purchase or are expected to pay dividends soon after their purchase. Principal Risks The fund may not achieve its objective(s), and it is not intended to be a complete investment program. The value of the fund s investments that supports your share value may decrease. If between the time you purchase shares and the time you sell shares the value of the fund s investments decreases, you will lose money. Investment values can decrease for a number of reasons. Conditions affecting the overall economy, specific industries or companies in which the fund invests can be worse than expected, and investments may fail to perform as the subadviser expects. As a result, the value of your shares may decrease. Purchase and redemption activities by fund shareholders may impact the management of the fund and its ability to achieve its investment objective(s). The redemption by one or more large shareholders or groups of shareholders of their holdings in the fund could have an adverse impact on the remaining shareholders in the fund including by accelerating the realization of capital gains and increasing the fund s transaction costs. The principal risks of investing in the fund are: Virtus Ceredex Large-Cap Value Equity Fund 2

> Depositary Receipts Risk. The risk that investments in foreign companies through depositary receipts will expose the fund to the same risks as direct investment in securities of foreign issuers. > Equity Securities Risk. The risk that events negatively affecting issuers, industries or financial markets in which the fund invests will impact the value of the stocks held by the fund and, thus, the value of the fund s shares over short or extended periods. Investments in a particular style or in small or medium-sized companies may enhance that risk. > Large Market Capitalization Companies Risk. The value of investments in larger companies may not rise as much as investments in smaller companies, and larger companies may be unable to respond quickly to competitive challenges, such as changes in technology and consumer tastes. > Market Volatility Risk. The risk that the value of the securities in which the fund invests may go up or down in response to the prospects of individual issuers and/or general economic conditions. Such price changes may be temporary or may last for extended periods. > Portfolio Turnover Risk. The risk that the fund s principal investment strategies will result in a consistently high portfolio turnover rate. See the Portfolio Turnover section above for more information about the impact that portfolio turnover can have on your investment. > Sector Focused Investing Risk. The risk that events negatively affecting a particular market sector in which the fund focuses its investments will cause the value of the fund s shares to decrease, perhaps significantly. > Value Stocks Risk. The risk that the fund will underperform when value investing is out of favor or that the fund s investments will not appreciate in value as anticipated. Performance Information The bar chart and table below provide some indication of the potential risks of investing in the fund. The fund s past performance, before and after taxes, is not necessarily an indication of how the fund will perform in the future. The fund has adopted the past performance of the Predecessor Fund as its own. The Predecessor Fund and the fund have identical investment objectives and strategies. The bar chart shows changes in the fund s performance from year to year over a 10-year period. The table shows how the fund s average annual returns compare to those of a broad-based securities market index. Updated performance information is available at virtus.com or by calling 800-243-1574. As of the date of this prospectus, Class T Shares had not begun operations; therefore, performance information for Class T Shares is not shown here. Calendar year total returns for Class I Shares Returns do not reflect sales charges applicable to other share classes and would be lower if they did. Annual Return (%) 40 20 0-20 3.75 24.65 18.28-1.49 16.39 34.19 11.08-4.62 15.45-40 2007-32.32 2008 2009 2010 2011 2012 2013 2014 2015 2016 Best Quarter: Q2/2009: 15.26% Worst Quarter: Q4/2008: -18.95% Year-to-date performance (through March 31, 2017) is 3.38% 3 Virtus Ceredex Large-Cap Value Equity Fund

Average Annual Total Returns (for the periods ended 12/31/16) Returns reflect deduction of maximum sales charges and full redemption at end of periods shown. 1 Year 5 Years 10 Years Since Inception Class R6 (8/1/14) Class I Return Before Taxes 15.45% 13.82% 6.90% Return After Taxes on Distributions 14.91% 11.68% 5.44% Return After Taxes on Distributions and Sale of Fund Shares 9.19% 10.60% 5.19% Class A Return Before Taxes 8.57% 12.18% 5.96% Class C Return Before Taxes 14.57% 12.92% 5.94% Class R6 Shares Return Before Taxes 15.77% 7.12% Russell 1000 Value Index (reflects no deduction for fees, expenses or taxes) 17.34% 14.80% 5.72% 8.08% The Russell 1000 Value Index is a market capitalization-weighted index of value-oriented stocks of the 1,000 largest companies in the Russell Universe, which comprises the 3,000 largest U.S. companies. The index is calculated on a total-return basis with dividends reinvested. The index is unmanaged and not available for direct investment. After-tax returns are calculated using the historical highest individual federal marginal income tax rates and do not reflect the impact of state and local taxes. After-tax returns are shown only for Class I Shares; after-tax returns for other classes will vary. Actual after-tax returns depend on the investor s tax situation and may differ from those shown. After-tax returns are not relevant to investors who hold fund shares in tax-deferred accounts or to shares held by non-taxable entities. Management The fund s investment adviser is Virtus Fund Advisers, LLC. The fund s subadviser is Ceredex Value Advisors LLC ( Ceredex ). Portfolio Management > Mills Riddick, CFA, Chief Investment Officer of Ceredex, has managed the fund since 1995. Purchase and Sale of Fund Shares Minimum initial investments applicable to Class A and Class C Shares: $2,500, generally $100 for Individual Retirement Accounts (IRAs), systematic purchase or exchange accounts No minimum for defined contribution plans, asset-based fee programs, profit-sharing plans or employee benefit plans Minimum additional investments applicable to Class A and Class C Shares: $100, generally No minimum for defined contribution plans, asset-based fee programs, profit-sharing plans or employee benefit plans For Class I Shares, the minimum initial purchase is $100,000; there is no minimum for additional purchases. Virtus Ceredex Large-Cap Value Equity Fund 4

Class R6 Shares are available only to the following investors without a minimum initial investment or minimum additional purchases: certain employer-sponsored retirement plans, including Section 401(k), 403(b) and 457, profit-sharing, money purchase pension and defined benefit plans and non-qualified deferred compensation plans, in each case provided that plan level or omnibus accounts are held on the books of the fund. Other institutional investors may be permitted to purchase Class R6 Shares subject to the fund s determination of eligibility and may be subject to a $2,500,000 minimum initial investment requirement. Class T Shares are available only through financial intermediaries. Your financial intermediary will provide you with the information you need to open an account and to buy or sell Class T Shares. In general, you may buy or sell shares of the fund by mail or telephone on any business day. You also may buy and sell shares through a financial advisor, broker-dealer or other financial intermediary. Taxes The fund s distributions are taxable to you as either ordinary income or capital gains, except when your investment is through a tax-deferred arrangement, such as a 401(k) plan or an individual retirement account. Such tax-deferred arrangements may be taxed later upon withdrawal of monies from those arrangements. Payments to Broker-Dealers and Other Financial Intermediaries If you purchase the fund through a broker-dealer or other financial intermediary (such as a bank), the fund and its related companies may pay the intermediary for the sale of fund shares and related services. These payments may create a conflict of interest by influencing the broker-dealer or other intermediary and your financial advisor to recommend the fund over another investment. No compensation, administrative payments, sub-transfer agency payments or service payments are paid to brokers or other entities from fund assets or the Distributor s or an affiliate s resources on sales of or investments in Class R6 Shares. Class R6 Shares do not carry sales commissions or pay Rule 12b-1 fees, or make payments to brokers or other entities to assist in, or in connection with, the sale of the fund s shares. Ask your financial advisor or visit your financial intermediary s Web site for more information. 5 Virtus Ceredex Large-Cap Value Equity Fund

Virtus Ceredex Mid-Cap Value Equity Fund Investment Objective The fund has an investment objective of seeking to provide capital appreciation. As a secondary goal, the fund also seeks to provide current income. Fees and Expenses The tables below illustrate the fees and expenses that you may pay if you buy and hold shares of the fund. You may qualify for sales charge discounts if you and your family invest, or agree to invest in the future, at least $50,000 in Virtus Funds. You may qualify for sales charge discounts in Class T Shares if you invest at least $250,000 in the fund. Information about these and other discounts is available: (i) from your financial advisor or other financial intermediary; (ii) under Sales Charges on page 196 of the fund s statutory prospectus; (iii) with respect to purchase of shares through specific intermediaries, in Appendix A to the fund s statutory prospectus, entitled Intermediary Sales Charge Discounts and Waivers; and (iv) under Alternative Purchase Arrangements on page 131 of the fund s statement of additional information. The Virtus Ceredex Mid-Cap Value Equity Fund, a series of Virtus Asset Trust, is the successor of the RidgeWorth Ceredex Mid-Cap Value Equity Fund, a series of RidgeWorth Funds ( Predecessor Fund ), resulting from a reorganization of the Predecessor Fund with and into the fund. Shareholder Fees (fees paid directly from your investment) Class A Class C Class I Class R6 Class T Maximum Sales Charge (load) Imposed on Purchases (as a percentage of offering price) 5.75% None None None 2.50% Maximum Deferred Sales Charge (load) (as a percentage of the lesser of purchase price or redemption proceeds) None 1.00% (a) None None None Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment) Class A Class C Class I Class R6 Class T Management Fees 0.69% 0.69% 0.69% 0.69% 0.69% Distribution and Shareholder Servicing (12b-1) Fees 0.25% 1.00% None None 0.25% Other Expenses 0.43% (b) 0.25% (b) 0.40% (b) 0.23% (b) 0.43% (c) Acquired Fund Fees and Expenses 0.01% 0.01% 0.01% 0.01% 0.01% Total Annual Fund Operating Expenses 1.38% 1.95% 1.10% 0.93% 1.38% Less: Fee Waivers and/or Expense Reimbursements (d) 0.00% -0.15% -0.01% -0.13% 0.00% Total Annual Fund Operating Expenses After Fee Waivers and/or Expense Reimbursements (d) 1.38% 1.80% 1.09% 0.80% 1.38% (a) (b) (c) (d) The deferred sales charge is imposed on Class C Shares redeemed during the first year only. Restated to reflect current fees and expenses. Estimated for current fiscal year, as annualized. The fund s investment adviser has contractually agreed to limit the fund s total operating expenses (excluding front-end or contingent deferred loads, taxes, leverage expenses, interest, brokerage commissions, expenses incurred in connection with any merger or reorganization, unusual or infrequently occurring expenses (such as litigation) and acquired fund fees and expenses, if any) so that such expenses do not exceed 1.38% for Class A Shares, 1.79% for Class C Shares, 1.08% for Class I Shares, 0.79% for Class R6 Shares and 1.38% for Class T Shares through July 31, 2019. Following the contractual period, the adviser may discontinue these expense reimbursement arrangements at any time. Under certain conditions, the adviser may recapture operating expenses reimbursed under these arrangements for a period of three years following the date on which such reimbursement occurred. Virtus Ceredex Mid-Cap Value Equity Fund 6

Example This example is intended to help you compare the cost of investing in the fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the fund for the time periods indicated and then redeem all of your shares at the end of those periods. It shows your costs if you sold your shares at the end of the period or continued to hold them. The example also assumes that your investment has a 5% return each year, that the fund s operating expenses remain the same and that the expense reimbursement agreement remains in place for the contractual period. Although your actual costs may be higher or lower, based on these assumptions your costs would be: Share Status 1 Year 3 Years 5 Years 10 Years Class A Sold or Held $707 $987 $1,287 $2,137 Sold $283 $582 $1,024 $2,250 Class C Held $183 $582 $1,024 $2,250 Class I Sold or Held $111 $348 $ 604 $1,338 Class R6 Sold or Held $ 82 $270 $ 489 $1,119 Class T Sold or Held $387 $676 $ 986 $1,866 Portfolio Turnover The fund pays transaction costs, such as commissions, when it buys and sells securities (or turns over its portfolio). A higher portfolio turnover rate may indicate higher transaction costs and may result in higher taxes when fund shares are held in a taxable account. These costs, which are not reflected in annual fund operating expenses or in the example, affect the fund s performance. During the most recent fiscal year, the Predecessor Fund s portfolio turnover rate was 108% of the average value of its portfolio. Investments, Risks and Performance Principal Investment Strategies Under normal circumstances, the fund invests at least 80% of its net assets (plus any borrowings for investment purposes) in U.S.-traded equity securities of mid-capitalization companies. U.S.-traded equity securities may include American Depositary Receipts ( ADRs ). The subadviser considers mid-capitalization companies to be companies with market capitalizations generally within those of companies in the Russell Midcap Index. As of March 31, 2017, the market capitalization range of the companies in the Russell Midcap Index was $58.2 million to $63.7 billion. As a result of its investment strategy, the fund s portfolio turnover rate may be 100% or more and the fund may focus its investments in one or more sectors. In selecting investments for purchase and sale, the subadviser chooses companies that it believes are undervalued in the market relative to the industry sector and the company s own valuation history. The subadviser evaluates potential catalysts that may cause an upward re-rating of the stock s valuation. The common stocks purchased for the fund generally pay dividends at the time of purchase or are expected to pay dividends soon after their purchase. Principal Risks The fund may not achieve its objective(s), and it is not intended to be a complete investment program. The value of the fund s investments that supports your share value may decrease. If between the time you purchase shares and the time you sell shares the value of the fund s investments decreases, you will lose money. Investment values can decrease for a number of reasons. Conditions affecting the overall economy, specific industries or companies in which the fund invests can be worse than expected, and investments may fail to perform as the subadviser expects. As a result, the value of your shares may decrease. Purchase and redemption activities by fund shareholders may impact the management of the fund and its ability to achieve its investment objective(s). The redemption by one or more large shareholders or groups of shareholders of their holdings in the fund could have an adverse impact on the remaining shareholders in the fund including by accelerating the realization of capital gains and increasing the fund s transaction costs. The principal risks of investing in the fund are: > Depositary Receipts Risk. The risk that investments in foreign companies through depositary receipts will expose the fund to the same risks as direct investment in securities of foreign issuers. 7 Virtus Ceredex Mid-Cap Value Equity Fund

> Equity Securities Risk. The risk that events negatively affecting issuers, industries or financial markets in which the fund invests will impact the value of the stocks held by the fund and, thus, the value of the fund s shares over short or extended periods. Investments in a particular style or in small or medium-sized companies may enhance that risk. > Market Volatility Risk. The risk that the value of the securities in which the fund invests may go up or down in response to the prospects of individual issuers and/or general economic conditions. Such price changes may be temporary or may last for extended periods. > Medium Market Capitalization Risk. The risk that the fund s investments in medium market capitalization companies will increase the volatility and risk of loss to the fund, as compared with investments in larger, more established companies. > Portfolio Turnover Risk. The risk that the fund s principal investment strategies will result in a consistently high portfolio turnover rate. See the Portfolio Turnover section above for more information about the impact that portfolio turnover can have on your investment. > Sector Focused Investing Risk. The risk that events negatively affecting a particular market sector in which the fund focuses its investments will cause the value of the fund s shares to decrease, perhaps significantly. > Value Stocks Risk. The risk that the fund will underperform when value investing is out of favor or that the fund s investments will not appreciate in value as anticipated. Performance Information The bar chart and table below provide some indication of the potential risks of investing in the fund. The fund s past performance, before and after taxes, is not necessarily an indication of how the fund will perform in the future. The fund has adopted the past performance of the Predecessor Fund as its own. The Predecessor Fund and the fund have identical investment objectives and strategies. The bar chart shows changes in the fund s performance from year to year over a 10-year period. The table shows how the fund s average annual returns compare to those of a broad-based securities market index. Updated performance information is available at virtus.com or by calling 800-243-1574. As of the date of this prospectus, Class T Shares had not begun operations; therefore, performance information for Class T Shares is not shown here. Calendar year total returns for Class I Shares Returns do not reflect sales charges applicable to other share classes and would be lower if they did. 60 46.98 Annual Return (%) 30 0-30 5.43-34.79 27.66-7.31 21.79 31.21 11.00-6.00 20.16-60 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Best Quarter: Q3/2009: 24.79% Worst Quarter: Q3/2011: -24.11% Year-to-date performance (through March 31, 2017) is 5.16% Virtus Ceredex Mid-Cap Value Equity Fund 8

Average Annual Total Returns (for the periods ended 12/31/16) Returns reflect deduction of maximum sales charges and full redemption at end of periods shown. 1 Year 5 Years 10 Years Since Inception Class R6 (8/1/14) Class I Return Before Taxes 20.16% 14.91% 9.13% Return After Taxes on Distributions 18.38% 12.32% 6.64% Return After Taxes on Distributions and Sale of Fund Shares 12.06% 11.02% 6.34% Class A Return Before Taxes 12.94% 13.24% 8.17% Class C Return Before Taxes 19.28% 14.08% 8.20% Class R6 Shares Return Before Taxes 20.53% 8.14% Russell Midcap Value Index (reflects no deduction for fees, expenses or taxes) 20.00% 15.70% 7.59% 8.49% The Russell Midcap Value Index is a market capitalization-weighted index of medium-capitalization, value-oriented stocks. The index is calculated on a total-return basis with dividends reinvested. The index is unmanaged and not available for direct investment. After-tax returns are calculated using the historical highest individual federal marginal income tax rates and do not reflect the impact of state and local taxes. After-tax returns are shown only for Class I Shares; after-tax returns for other classes will vary. Actual after-tax returns depend on the investor s tax situation and may differ from those shown. After-tax returns are not relevant to investors who hold fund shares in tax-deferred accounts or to shares held by non-taxable entities. Management The fund s investment adviser is Virtus Fund Advisers, LLC. The fund s subadviser is Ceredex Value Advisors LLC ( Ceredex ). Portfolio Management > Don Wordell, CFA, Managing Director of Ceredex, has managed the fund since 2001. Purchase and Sale of Fund Shares Minimum initial investments applicable to Class A and Class C Shares: $2,500, generally $100 for Individual Retirement Accounts (IRAs), systematic purchase or exchange accounts No minimum for defined contribution plans, asset-based fee programs, profit-sharing plans or employee benefit plans Minimum additional investments applicable to Class A and Class C Shares: $100, generally No minimum for defined contribution plans, asset-based fee programs, profit-sharing plans or employee benefit plans For Class I Shares, the minimum initial purchase is $100,000; there is no minimum for additional purchases. 9 Virtus Ceredex Mid-Cap Value Equity Fund

Class R6 Shares are available only to the following investors without a minimum initial investment or minimum additional purchases: certain employer-sponsored retirement plans, including Section 401(k), 403(b) and 457, profit-sharing, money purchase pension and defined benefit plans and non-qualified deferred compensation plans, in each case provided that plan level or omnibus accounts are held on the books of the fund. Other institutional investors may be permitted to purchase Class R6 Shares subject to the fund s determination of eligibility and may be subject to a $2,500,000 minimum initial investment requirement. Class T Shares are available only through financial intermediaries. Your financial intermediary will provide you with the information you need to open an account and to buy or sell Class T Shares. In general, you may buy or sell shares of the fund by mail or telephone on any business day. You also may buy and sell shares through a financial advisor, broker-dealer or other financial intermediary. Taxes The fund s distributions are taxable to you as either ordinary income or capital gains, except when your investment is through a tax-deferred arrangement, such as a 401(k) plan or an individual retirement account. Such tax-deferred arrangements may be taxed later upon withdrawal of monies from those arrangements. Payments to Broker-Dealers and Other Financial Intermediaries If you purchase the fund through a broker-dealer or other financial intermediary (such as a bank), the fund and its related companies may pay the intermediary for the sale of fund shares and related services. These payments may create a conflict of interest by influencing the broker-dealer or other intermediary and your financial advisor to recommend the fund over another investment. No compensation, administrative payments, sub-transfer agency payments or service payments are paid to brokers or other entities from fund assets or the Distributor s or an affiliate s resources on sales of or investments in Class R6 Shares. Class R6 Shares do not carry sales commissions or pay Rule 12b-1 fees, or make payments to brokers or other entities to assist in, or in connection with, the sale of the fund s shares. Ask your financial advisor or visit your financial intermediary s Web site for more information. Virtus Ceredex Mid-Cap Value Equity Fund 10

Virtus Ceredex Small-Cap Value Equity Fund Investment Objective The fund has an investment objective of seeking to provide capital appreciation. As a secondary goal, the fund also seeks to provide current income. Fees and Expenses The tables below illustrate the fees and expenses that you may pay if you buy and hold shares of the fund. You may qualify for sales charge discounts if you and your family invest, or agree to invest in the future, at least $50,000 in Virtus Funds. You may qualify for sales charge discounts in Class T Shares if you invest at least $250,000 in the fund. Information about these and other discounts is available: (i) from your financial advisor or other financial intermediary; (ii) under Sales Charges on page 196 of the fund s statutory prospectus; (iii) with respect to purchase of shares through specific intermediaries, in Appendix A to the fund s statutory prospectus, entitled Intermediary Sales Charge Discounts and Waivers; and (iv) under Alternative Purchase Arrangements on page 131 of the fund s statement of additional information. The Virtus Ceredex Small-Cap Value Equity Fund, a series of Virtus Asset Trust, is the successor of the RidgeWorth Ceredex Small Cap Value Equity Fund, a series of RidgeWorth Funds ( Predecessor Fund ), resulting from a reorganization of the Predecessor Fund with and into the fund. Shareholder Fees (fees paid directly from your investment) Class A Class C Class I Class T Maximum Sales Charge (load) Imposed on Purchases (as a percentage of offering price) 5.75% None None 2.50% Maximum Deferred Sales Charge (load) (as a percentage of the lesser of purchase price or redemption proceeds) None 1.00% (a) None None Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment) Class A Class C Class I Class T Management Fees 0.83% 0.83% 0.83% 0.83% Distribution and Shareholder Servicing (12b-1) Fees 0.25% 1.00% None 0.25% Other Expenses 0.40% (b) 0.22% (b) 0.40% (b) 0.40% (c) Total Annual Fund Operating Expenses 1.48% 2.05% 1.23% 1.48% Less: Fee Waivers and/or Expense Reimbursements (d) 0.00% -0.15% 0.00% 0.00% Total Annual Fund Operating Expenses After Fee Waivers and/or Expense Reimbursements (d) 1.48% 1.90% 1.23% 1.48% (a) (b) (c) (d) The deferred sales charge is imposed on Class C Shares redeemed during the first year only. Restated to reflect current fees and expenses. Estimated for current fiscal year, as annualized. The fund s investment adviser has contractually agreed to limit the fund s total operating expenses (excluding front-end or contingent deferred loads, taxes, leverage expenses, interest, brokerage commissions, expenses incurred in connection with any merger or reorganization, unusual or infrequently occurring expenses (such as litigation) and acquired fund fees and expenses, if any) so that such expenses do not exceed 1.55% for Class A Shares, 1.90% for Class C Shares, 1.24% for Class I Shares and 1.55% for Class T Shares through July 31, 2019. Following the contractual period, the adviser may discontinue these expense reimbursement arrangements at any time. Under certain conditions, the adviser may recapture operating expenses reimbursed under these arrangements for a period of three years following the date on which such reimbursement occurred. 11 Virtus Ceredex Small-Cap Value Equity Fund

Example This example is intended to help you compare the cost of investing in the fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the fund for the time periods indicated and then redeem all of your shares at the end of those periods. It shows your costs if you sold your shares at the end of the period or continued to hold them. The example also assumes that your investment has a 5% return each year, that the fund s operating expenses remain the same and that the expense reimbursement agreement remains in place for the contractual period. Although your actual costs may be higher or lower, based on these assumptions your costs would be: Share Status 1 Year 3 Years 5 Years 10 Years Class A Sold or Held $717 $1,016 $1,336 $2,242 Sold $293 $ 613 $1,075 $2,355 Class C Held $193 $ 613 $1,075 $2,355 Class I Sold or Held $125 $ 390 $ 676 $1,489 Class T Sold or Held $397 $ 706 $1,038 $1,974 Portfolio Turnover The fund pays transaction costs, such as commissions, when it buys and sells securities (or turns over its portfolio). A higher portfolio turnover rate may indicate higher transaction costs and may result in higher taxes when fund shares are held in a taxable account. These costs, which are not reflected in annual fund operating expenses or in the example, affect the fund s performance. During the most recent fiscal year, the Predecessor Fund s portfolio turnover rate was 29% of the average value of its portfolio. Investments, Risks and Performance Principal Investment Strategies Under normal circumstances, the fund invests at least 80% of its net assets (plus any borrowings for investment purposes) in U.S.-traded equity securities of small-capitalization companies. U.S.-traded equity securities may include American Depositary Receipts ( ADRs ). The subadviser considers small-capitalization companies to be both companies with market capitalizations between $50 million and $3 billion and companies with market capitalizations generally within those of companies in the Russell 2000 Value Index. As of March 31, 2017, the market capitalization range of the companies in the Russell 2000 Value Index was $30.4 million to $13.6 billion. As a result of its investment strategy, the fund may focus its investments in one or more sectors. In selecting investments for purchase and sale, the subadviser chooses companies that it believes are undervalued in the market relative to the industry sector and the company s own valuation history. The subadviser evaluates potential catalysts that may cause an upward re-rating of the stock s valuation. The common stocks purchased for the fund generally pay dividends at the time of purchase or are expected to pay dividends soon after their purchase. Principal Risks The fund may not achieve its objective(s), and it is not intended to be a complete investment program. The value of the fund s investments that supports your share value may decrease. If between the time you purchase shares and the time you sell shares the value of the fund s investments decreases, you will lose money. Investment values can decrease for a number of reasons. Conditions affecting the overall economy, specific industries or companies in which the fund invests can be worse than expected, and investments may fail to perform as the subadviser expects. As a result, the value of your shares may decrease. Purchase and redemption activities by fund shareholders may impact the management of the fund and its ability to achieve its investment objective(s). The redemption by one or more large shareholders or groups of shareholders of their holdings in the fund could have an adverse impact on the remaining shareholders in the fund including by accelerating the realization of capital gains and increasing the fund s transaction costs. The principal risks of investing in the fund are: > Depositary Receipts Risk. The risk that investments in foreign companies through depositary receipts will expose the fund to the same risks as direct investment in securities of foreign issuers. Virtus Ceredex Small-Cap Value Equity Fund 12

> Equity Securities Risk. The risk that events negatively affecting issuers, industries or financial markets in which the fund invests will impact the value of the stocks held by the fund and, thus, the value of the fund s shares over short or extended periods. Investments in a particular style or in small or medium-sized companies may enhance that risk. > Market Volatility Risk. The risk that the value of the securities in which the fund invests may go up or down in response to the prospects of individual issuers and/or general economic conditions. Such price changes may be temporary or may last for extended periods. > Sector Focused Investing Risk. The risk that events negatively affecting a particular market sector in which the fund focuses its investments will cause the value of the fund s shares to decrease, perhaps significantly. > Small Market Capitalization Companies Risk. The risk that the fund s investments in small market capitalization companies may be less liquid and more vulnerable to adverse business or economic developments, which may increase the volatility and risk of loss to the fund, as compared with investments in larger, more established companies. > Value Stocks Risk. The risk that the fund will underperform when value investing is out of favor or that the fund s investments will not appreciate in value as anticipated. Performance Information The bar chart and table below provide some indication of the potential risks of investing in the fund. The fund s past performance, before and after taxes, is not necessarily an indication of how the fund will perform in the future. The fund has adopted the past performance of the Predecessor Fund as its own. The Predecessor Fund and the fund have identical investment objectives and strategies. The bar chart shows changes in the fund s performance from year to year over a 10-year period. The table shows how the fund s average annual returns compare to those of a broad-based securities market index. Updated performance information is available at virtus.com or by calling 800-243-1574. As of the date of this prospectus, Class T Shares had not begun operations; therefore, performance information for Class T Shares is not shown here. Calendar year total returns for Class I Shares Returns do not reflect sales charges applicable to other share classes and would be lower if they did. Annual Return (%) 50 25 0-25 2.03-31.97 36.04 28.79-3.73 16.80 35.05 2.12-5.86 29.16-50 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Best Quarter: Q3/2009: 19.65% Worst Quarter: Q4/2008: -26.62% Year-to-date performance (through March 31, 2017) is 1.33% 13 Virtus Ceredex Small-Cap Value Equity Fund

Average Annual Total Returns (for the periods ended 12/31/16) Returns reflect deduction of maximum sales charges and full redemption at end of periods shown. Class I 1 Year 5 Years 10 Years Return Before Taxes 29.16% 14.39% 8.66% Return After Taxes on Distributions 27.59% 11.27% 6.38% Return After Taxes on Distributions and Sale of Fund Shares 17.81% 11.10% 6.62% Class A Return Before Taxes 21.37% 12.70% 7.70% Class C Return Before Taxes 28.33% 13.57% 7.86% Russell 2000 Value Index (reflects no deduction for fees, expenses or taxes) 31.74% 15.07% 6.26% The Russell 2000 Value Index is a market capitalization-weighted index of value-oriented stocks of the smallest 2,000 companies in the Russell universe, which comprises the 3,000 largest U.S. companies. The index is calculated on a total-return basis with dividends reinvested. The index is unmanaged and not available for direct investment. After-tax returns are calculated using the historical highest individual federal marginal income tax rates and do not reflect the impact of state and local taxes. After-tax returns are shown only for Class I Shares; after-tax returns for other classes will vary. Actual after-tax returns depend on the investor s tax situation and may differ from those shown. After-tax returns are not relevant to investors who hold fund shares in tax-deferred accounts or to shares held by non-taxable entities. Management The fund s investment adviser is Virtus Fund Advisers, LLC. The fund s subadviser is Ceredex Value Advisors LLC ( Ceredex ). Portfolio Management > Brett Barner, CFA, Managing Director of Ceredex, has managed the fund since 1994. Purchase and Sale of Fund Shares IMPORTANT NOTE: Shares of Virus Ceredex Small-Cap Value Fund are not currently available for purchase by new investors or for exchange from other Virtus Funds by existing investors. Minimum initial investments applicable to Class A and Class C Shares: $2,500, generally $100 for Individual Retirement Accounts (IRAs), systematic purchase or exchange accounts No minimum for defined contribution plans, asset-based fee programs, profit-sharing plans or employee benefit plans Minimum additional investments applicable to Class A and Class C Shares: $100, generally No minimum for defined contribution plans, asset-based fee programs, profit-sharing plans or employee benefit plans For Class I Shares, the minimum initial purchase is $100,000; there is no minimum for additional purchases. Class T Shares are available only through financial intermediaries. Your financial intermediary will provide you with the information you need to open an account and to buy or sell Class T Shares. In general, you may buy or sell shares of the fund by mail or telephone on any business day. You also may buy and sell shares through a financial advisor, broker-dealer or other financial intermediary. Virtus Ceredex Small-Cap Value Equity Fund 14