S&P 500 Industry Briefing: Biotechnology

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S&P Industry Briefing: Biotechnology January, 218 Dr. Ed Yardeni 16-972-7683 eyardeni@ Joe Abbott 732-497-36 jabbott@ Please visit our sites at www. blog. thinking outside the box

Table Of Contents Table Of Contents S&P Biotechnology Stock Price Index 1 Earnings 2 Revenues & Margins 3 Earnings Growth & Valuation 4 January, 218 / S&P Industry Briefing: Biotechnology www.

Stock Price Index 47 47 367 Figure 1. S&P BIOTECHNOLOGY STOCK PRICE INDEX* (ABBV ALXN AMGN BIIB CELG GILD INCY REGN VRTX) 1/ 47 47 367 277 277 187 187 97 97 7 7 2-day moving average. * Ratio scale. Source: Standard & Poor s and Haver Analytics. 1 12 9 6 3 Figure 2. S&P BIOTECHNOLOGY INDEX, FORWARD EARNINGS, & VALUATION Biotechnology Index 1//18 Blue Angels Implied Price Index* /17 x x2 1/ x1 1 12 9 6 3 * Implied price index calculated using forward earnings times forward P/Es. Source: Standard & Poor s and Thomson Reuters I/B/E/S. Page 1 / January, 218 / S&P Industry Briefing: Biotechnology www.

Earnings 36 3 24 Figure 3. S&P BIOTECHNOLOGY OPERATING EARNINGS PER SHARE (analysts average forecasts, ratio scale) 17 18 19 36 3 24 18 12 Consensus Forecasts Annual estimates Forward earnings* 18 12 6 6 * Time-weighted average of consensus estimates for current year and next year. Monthly through December 2, then weekly. 6 Figure 4. S&P BIOTECHNOLOGY NET EARNINGS REVISIONS* 6 2 2 Dec -2 - NERI Oct 16.6 Nov.1 Dec -3.4-2 - * Three-month moving average of the number of forward earnings estimates up less number of estimates down, expressed as a percentage of the total number of forward earnings estimates. Page 2 / January, 218 / S&P Industry Briefing: Biotechnology www.

8 7 Figure. Revenues & Margins S&P BIOTECHNOLOGY REVENUES PER SHARE (analysts average forecasts, ratio scale) 17 18 19 8 7 Consensus Forecasts Annual estimates Forward revenues* 2 2 1 24 2 26 27 28 29 21 211 212 213 214 21 216 217 218 219 1 * Time-weighted average of consensus estimates for current year and next year. Monthly through December 2, then weekly. 46 44 Figure 6. S&P BIOTECHNOLOGY PROJECTED PROFIT MARGIN (using analysts average earnings and revenues forecasts) 17 46 44 42 Consensus Forecasts Annual estimates Forward profit margin* (37.9) 18 19 42 38 36 38 36 34 34 32 32 3 3 28 28 26 24 24 2 26 27 28 29 21 211 212 213 214 21 216 217 218 219 26 24 * Time-weighted average of the consensus estimates for current year and next year. Monthly through December 2, weekly thereafter. Page 3 / January, 218 / S&P Industry Briefing: Biotechnology www.

3 Figure 7. Earnings Growth & Valuation S&P BIOTECHNOLOGY STRG, STEG, & LTEG (percent) LTEG (12.8) STEG (3.7) STRG (3.) 3 2 2 1 1-1 7 6 Note: STEG is year-ahead forward consensus expected short-term earnings growth. STRG is year-ahead forward consensus expected short-term revenue growth. LTEG is five-year consensus expected long-term earnings growth. Monthly data through 2, weekly thereafter. Figure 8. S&P BIOTECHNOLOGY VALUATION -1 7 6 4 Relative P/E and PEG capped at 3. Forward P/E* (14.) 4 3 3 2 2 1 1 3. 3. 2. 2. 1. 1... Relative P/E** (.8) PEG Ratio*** (1.1) 3. 3. 2. 2. 1. 1... * Price divided by 12-month forward consensus expected operating earnings per share. ** Sector or industry forward P/E relative to S&P forward P/E. *** Sector or industry forward P/E relative to sector or industry consensus -year LTEG forecast. Page 4 / January, 218 / S&P Industry Briefing: Biotechnology www.

Copyright (c) 218. All rights reserved. The information contained herein has been obtained from sources believed to be reliable, but is not necessarily complete and its accuracy cannot be guaranteed. No representation or warranty, express or implied, is made as to the fairness, accuracy, completeness, or correctness of the information and opinions contained herein. The views and the other information provided are subject to change without notice. All reports posted on www., blog., http://blog. and YRI s Apps for ipads and iphones are issued without regard to the specific investment objectives, financial situation, or particular needs of any specific recipient and are not to be construed as a solicitation or an offer to buy or sell any securities or related financial instruments. Past performance is not necessarily a guide to future results. Company fundamentals and earnings may be mentioned occasionally, but should not be construed as a recommendation to buy, sell, or hold the company s stock. Predictions, forecasts, and estimates for any and all markets should not be construed as recommendations to buy, sell, or hold any security--including mutual funds, futures contracts, and exchange traded funds, or any similar instruments. The text, images, and other materials contained or displayed on any product, service, report, email or website are proprietary to and constitute valuable intellectual property. No material from any part of www., blog., http://blog. and YRI s Apps for ipads and iphones may be downloaded, transmitted, broadcast, transferred, assigned, reproduced or in any other way used or otherwise disseminated in any form to any person or entity, without the explicit written consent of All unauthorized reproduction or other use of material from Yardeni Research, Inc. shall be deemed willful infringement(s) of this copyright and other proprietary and intellectual property rights, including but not limited to, rights of privacy. Yardeni Research, Inc. expressly reserves all rights in connection with its intellectual property, including without limitation the right to block the transfer of its products and services and/or to track usage thereof, through electronic tracking technology, and all other lawful means, now known or hereafter devised. reserves the right, without further notice, to pursue to the fullest extent allowed by the law any and all criminal and civil remedies for the violation of its rights. The recipient should check any email and any attachments for the presence of viruses. accepts no liability for any damage caused by any virus transmitted by this company s emails, website, blog and Apps. Additional information available on request. requests@