Managing Spasticity in Multiple Sclerosis

MS Practice Update: Managing Spasticity in Multiple Sclerosis EXHIBITOR PROSPECTUS Friday, May 22, 2009 7:15AM 4:00PM Location: Beechwood Hotel Worcester, MA Sponsored by The MS Center at UMASS Memorial and The Department of Continuing Medical Education at UMASS Medical School. 1

7:15 8:00 AM Registration & Breakfast PROGRAM AGENDA* Friday, May 22, 2009 8:00 8:05 AM Welcome & Introduction: Peter Riskind, MD, PhD 8: 05 8:40 The Impact of spasticity in the morbidity, mortality & quality of life in MS patients Peter Riskind, MD, PhD 8:40 9:25 AM The pathophysiology of spasticity, the diagnosis & assessment of spasticity in MS patients Carolina Ionete, MD, PhD 9:25 10:05 AM Treatment Options for Spasticity: Mechanism of action and common side effects of the different therapies Neeta Garg, MD 10:05 10:20 AM Question & Answer Session 10:20 11:00 AM Coffee and Exhibitor Break 11:00 11:45 AM Role of physical therapy in the management of spasticity: Movement dysfunction in MS Susan E. Bennett, PT, EdD, NCS, MSCS 11:45 AM Noon Question & Answer Session Noon 1:00 PM Lunch and Exhibitor Break 1:00 2:00 PM Chemodenervation: Understanding the mechanism of action of botulinum toxins and their role in the management of spasticity. Nancy Fontneau, MD 2:00 2:40 PM The use of Baclofen Intrathecal Pump in the treatment of spasticity in multiple sclerosis: Treatment rationale and possible side effects Carolina Ionete, MD, PhD 2:40 3:20 PM Patient evaluation and surgical technique of Intrathecal Baclofen pump placement John Weaver, MD 3:20 3:30 PM Question & Answer Session 3:30 3:50 PM Botulinum Toxin and Intrathecal Baclofen pump demonstration sessions Colleen Emmett, PT and All Faculty 3:55 PM Wrap up and evaluations 4:00 PM Adjourn *Agenda subject to change without notice, Last Updated 10/1/08. CONFERENCE OVERVIEW This full day intensive review/course in spasticity management will enable the participants to: Recognize issues commonly associated with spasticity in patients with MS Enhance the ability to assess a patient with spasticity Review non pharmacologic interventions & medications currently available for multi approach management of spasticity in MS patients Discuss evidence based approaches of palliative care of spasticity Recommend treatment options for patients with spasticity TARGET AUDIENCE This conference has been designed for physicians (neurologists, physiatrists, other specialties ), nurses, mid levels, students and residents specializing in the care of patients with Multiple Sclerosis. CONFERENCE VENUE The Beechwood Hotel, 363 Plantation Street, Worcester, MA www.beechwoodhotel.com CONFERENCE MANAGEMENT CONTACT Jacqueline Blow, Program Coordinator Office of Continuing Medical Education, UMASS Medical School P: (508) 856 2530F: (508) 856 6838 E: Jacqueline.Blow@Umassmed.edu 2

ASSIGNMENT OF EXHIBIT SPACE Exhibition space will be guaranteed once the Application and payment is received. Location and assignment of booth space will be determined by an authorized representative of UMMS. Exhibitor Fee: 8 x 10 for May 22, 2009 $1,500. Exhibitor Fees include: Exhibit space, including one skirted 8 table Company identification sign Company name and description listed in the on site Program Guide/Conference Syllabus Electrical hookups as requested Two passes to the Conference Exhibitors may use their own booth, pop up booth, back drops, signage, and attention getting devices. Payment in full (check, money order, VISA, Discover, American Express or Master Card) must accompany the Application. Applications and payments must be received no later than 4:00 pm on May 8, 2009. If the exhibitor cancels their booth space request before the date of May 8, 2009, 50% of their payment will be forfeited. If the Exhibitor cancels on or before May 22, 2009, all monies will be forfeited. There is no rebate of fees for no shows. AGREEMENT TO RULES Each exhibitor agrees to abide by the Rules published in this document. Every agreement and representation must be in writing and signed by an authorized representative of the Exhibiting company to be binding. The Agreement cannot be modified or canceled by the Exhibitor without prior consent of the UMMS OCME. ELIGIBILITY TO EXHIBIT Products and services must be related to Multiple Sclerosis. Exhibitors will not be permitted to display outside the confines of their assigned space. Exhibitors may not sublet, share, exchange, assign or apportion any part of the exhibition space allotted. Exhibitors are not allowed to represent, advertise or distribute literature for the products or services of any other company or individual unless previously approved in writing by an authorized representative of the UMMS OCME. Exhibitors shall be solely responsible for compliance with the applicable provisions of the Americans with Disabilities ACT (ADA) with respect to exhibition space. EXHIBITOR INFORMATION Exhibitor agrees to indemnify, defend and hold UMMS, its officers, directors, agents, employees, parent, subsidiaries and affiliates, harmless for any damages or charges imposed for violations of any law, rule, regulation or ordinance, as well as, any failure to strictly comply with the applicable terms and conditions contained in the agreement between the Beechwood Hotel regarding the Exhibition Space. Further, Exhibitors shall at all times protect, indemnify, save, defend, and hold harmless UMMS and the Beechwood Hotel, its officers, directors, agents and employees against and from any and all loss, cost (including attorney fees), damage, liability, or expense, without limitation, arising from or out of or by reason of the activities of the Exhibitor, its employees, agents, business invitees, or guests, the use of the exhibition space (or any part thereof) or the exhibit or display itself, including without limitation, any property damage or of any accident or bodily injury or other occurrence to any person or persons, including the Exhibitor, its agents, employees, guests and business invitees. The Exhibitor understands that neither UMMS nor the Beechwood Hotel maintains insurance covering the Exhibitor s property and it is the sole responsibility of the Exhibitor to obtain such insurance. Booth Construction Obstructive displays are not permitted. UMMS OCME shall have full discretion and authority on the placement, arrangement, and appearance of the booth displayed by the Exhibitor, and may require the replacing or rearrangement of the booth within the exhibit space. Exhibitors and their agents shall not injure or deface the wall, floors, carpeting, and/or ceiling of the building or equipment provided by the resort. No pins, tacks, or adhesives of any kind are permitted on any wall, door or column. Any tape applied to the floor by the exhibitor must be approved by the UMMS conference management. If any damage appears, the Exhibitor is liable to the Beechwood Hotel. Services Provided to Exhibitors All services contracted by the Exhibitor from 3rd party vendors including without limitation shipping, Internet, electrical, telephone, security, and equipment rental, must be ordered and paid for by the Exhibitor. Please contact the Beechwood Hotel at (508) 856 8687 for these requests. Requirements of Booth Staff Each Exhibitor must have at least one representative operating the exhibit booth during all official exhibiting hours as published by UMMS. Exhibitors are asked not to conduct product demonstrations during scheduled sessions and must agree to immediately terminate if requested by UMMS conference management. 3

Exhibit Space Application 09/119 Exhibiting Company Name: Address: City / State / Zip: Contact Name: Contact Phone #: Fax #: On Site Contact (if different from above): Contact Email: Names of company representatives as they need to appear on a name badge for conference passes: Rep. 1: Rep. 2: Total Amount Due $. Payment by check made payable to University of Massachusetts Office of Continuing Medical Education. UMMS Tax ID: 043 167352 CREDIT CARD: Type of Credit Card VISA MC DISCOVER AMEX Credit Card # Exp. Name on Credit Card By signing here, I authorize the UMMS OCME to charge my credit card for the above sponsorship opportunity: I am an authorized representative of the Company with authority to sign this Application. Authorized officer name: Authorized officer signature: Title: Applications are considered binding and eligible only after the Application and payment are received and approved by the conference manager. By signing the Application, Exhibitor acknowledges that they have read, understand and will comply with the rules and regulations for exhibiting set forth in this Prospectus. Please complete entire Application, sign, and mail with check or fax with credit card information by May 8, 2009. LIABILITY AND INSURANCE The University of Massachusetts Medical School undertakes no duty to exercise care, nor does it assume any responsibility, for the protection and safety of the Exhibitor, its officers, agents, employees or guests or for their protection of the property of the Exhibitor or its representatives or property used in connection with the exhibition space, from theft or damage or destruction by fire, accident, or other cause. Small and easily portable articles shall be properly secured or removed after exhibition hours and placed in safekeeping by the Exhibitor. IN ALL CASES, EXHIBITORS ARE REQUIRED TO MAINTAIN ADEQUATE INSURANCE OR SELF INSURANCE COVERAGE AGAINST INJURIES TO PERSON AND DAMAGE TO OR LOSS OF PROPERTY AND MUST DO SO AT THEIR OWN EXPENSE. IT IS ESPECIALLY RECOMMENDED THAT ALL EXHIBITORS HAVE REPRESENTATIVES IN ATTEN DEANCE AT ALL TIMES WHEN THE EXHIBITS ARE OPEN AND ESPECIALLY WHEN EXHIBITS ARE BEING SET UP OR DISMANTLED, TO PROTECT THEM AGAINST LOSS OR DAMAGE. Cancellation by Exhibitor Should the Exhibitor be unable to occupy the exhibit space, notification of cancellation must be submitted in writing to UMMS conference management. If an Exhibitor cancels their booth space request between the date of Application and 4:00 pm May 8, 2009, 50% of their payment will be forfeited. If Exhibitor cancels on or after May 22, 2009, all monies will be forfeited. There is no rebate of fees for no shows Further, if an Exhibitor fails to install a display in the assigned exhibition space, or fails to otherwise occupy the space, or fails to pay the exhibit space fee, or fails to comply with other provisions of this Agreement, UMMS shall have the right without notice to the Exhibitor to take possession of said exhibition space and the Exhibitor agrees to pay any deficiency or any other loss or damage suffered by the UMMS OCME resulting from such failure to comply. Cancellation or Relocation of Conference In the event of cancellation or relocation of the conference, due to circumstances within UMMS control, the liability of UMMS shall be limited solely to a refund of any exhibition fee payments made to UMMS by the Exhibitor. In the event UMMS has no control over the cancellation or relocation of the Conference, UMMS shall have no liability of any kind. UMMS USE ONLY: Rec d Space Assignment Contact 4

Sponsorship Opportunities Conference Portfolio/Bag Sponsorship Investment: $2,000 An optional Conference Portfolio/Bag, if sponsored, would be given to each attendee upon registration. A Portfolio/Bag is usually kept and used by attendees long after the conference is over. Sponsoring companies receive recognition in conference materials. Continental Breakfast Sponsorship Investment: $1,500 Lunch Sponsorship Investment: $3,000 Refreshment Break Sponsorship Investment: $1,000 Application For Sponsorship SPONSOR INFORMATION Submit via Fax to 508.856.6838, attn: Jacqueline Blow, Program Coordinator or email: Jacqueline.Blow@Umassmed.edu List your Company name/contact information as you would like it to appear in any programs. Sponsoring Company Name: Address: City/State/Zip: Contact Name: Contact Email: Contact Phone #: Fax #: Total Amount Due $ Payment by check should be made payable to University of Massachusetts Office of Continuing Medical Education. CREDIT CARD: Type of Credit Card VISA MC DISCOVER AMEX Credit Card # Exp. Name on Credit Card By signing here, I authorize the UMMS OCME to charge my credit card for the above sponsorship opportunity: I am an authorized representative of the Company with authority to sign this Application. Authorized officer name: Authorized officer signature: Title: Applications for sponsorship must be received by May 8, 2009. 5