PRUDENTIAL PREMIER ADVISOR VARIABLE ANNUITY PRUDENTIAL PREMIER RETIREMENT VARIABLE ANNUITY PRUDENTIAL PREMIER INVESTMENT VARIABLE ANNUITY

PRUDENTIAL PREMIER ADVISOR VARIABLE ANNUITY PRUDENTIAL PREMIER RETIREMENT VARIABLE ANNUITY PRUDENTIAL PREMIER INVESTMENT VARIABLE ANNUITY PRUCO LIFE INSURANCE COMPANY PRUCO LIFE FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUCO LIFE INSURANCE COMPANY OF NEW JERSEY PRUCO LIFE OF NEW JERSEY FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT Supplement dated March 18, 2019 to Prospectuses dated April 30, 2018 This Supplement should be read in conjunction with the current Prospectus for your Annuity and should be retained for future reference. This Supplement is intended to update certain information in the Prospectus for the variable annuity you own and is not intended to be a prospectus or offer for any other variable annuity that you do not own. Defined terms used herein and not otherwise defined herein shall have the meanings given to them in the Prospectuses and Statements of Additional Information. Please check your Annuity Prospectus to determine which of the following changes affect the Annuity that you own. If you would like another copy of the current Annuity Prospectus, please call us at 1-888-PRU-2888. AST Emerging Managers Diversified Portfolio, AST Morgan Stanley Multi-Asset Portfolio, AST Wellington Management Real Total Return Portfolio Effective as of the close of business on April 26, 2019 (the Closure Date ), the AST Emerging Managers Diversified Portfolio, AST Morgan Stanley Multi-Asset Portfolio, and AST Wellington Management Real Total Return Portfolio (the Portfolios ) of Advanced Series Trust will be closed. As of the Closure Date, no additional Purchase Payments or requests for transfers of Account Value into the Sub-account(s) investing in the Portfolio(s) will be accepted from new or existing contract Owners, including those contract Owners who have Account Value invested in Sub-accounts investing in the Portfolio(s) as of the Closure Date. Dollar Cost Averaging and/or Auto-Rebalancing programs, if elected by a contract Owner prior to the Closure Date, will not be affected by the Closure unless a contract Owner withdraws or otherwise transfers his entire Account Value from the Sub-account investing in the Portfolio(s). The Board of Trustees of Advanced Series Trust recently approved the liquidation of the Portfolios to be effective on or about July 1, 2019. The liquidation is subject to the approval of a Plan of Substitution by shareholders of the Portfolios. On or prior to the liquidation date, a contract Owner may transfer Account Value allocated to the Portfolio(s) to another investment option permitted under a contract, without such transfer counting towards the number of permitted transfers per year. Under the Plan of Substitution, any Account Value not transferred to another investment option as of the liquidation date will be automatically transferred to the AST Government Money Market Portfolio Subaccount on the liquidation date. Any Account Value transferred from the Sub-account(s) investing in the Portfolio(s) as a result of the Plan of Substitution, including applicable transfers into or out of the AST Government Money Market Portfolio Sub-account, will not be counted as one of the free transfers allowed to contract Owners, provided that the transfer occurs prior to, or within 90 days following, the liquidation date. THIS SUPPLEMENT SHOULD BE READ AND RETAINED FOR FUTURE REFERENCE GENPRODSUP14

PRUCO LIFE INSURANCE COMPANY PRUCO LIFE FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUCO LIFE INSURANCE COMPANY OF NEW JERSEY PRUCO LIFE OF NEW JERSEY FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION VARIABLE ACCOUNT B Supplement dated March 15, 2019 to Prospectuses dated April 30, 2018 This Supplement should be read in conjunction with the current Prospectus for your Annuity and should be retained for future reference. This Supplement is intended to update certain information in the Prospectus for the variable annuity you own and is not intended to be a prospectus or offer for any other variable annuity that you do not own. Defined terms used herein and not otherwise defined herein shall have the meanings given to them in the Prospectuses and Statements of Additional Information. This Supplement contains information about changes for the AST Goldman Sachs Large-Cap Value Portfolio of the Advanced Series Trust. If you would like another copy of the current Annuity Prospectus, please call us at 1-888-PRU-2888. AST Goldman Sachs Large-Cap Value Portfolio - Merger: As described below, on or about April 29, 2019 (the Effective Date ), the AST Goldman Sachs Large-Cap Value Portfolio (the Target Portfolio ) will be merged into the AST T. Rowe Price Large-Cap Value Portfolio (the Acquiring Portfolio ) as noted below. All references to the AST Goldman Sachs Large-Cap Value Portfolio in your Annuity Prospectus should be disregarded after the Effective Date. Target Portfolio AST Goldman Sachs Large-Cap Value Portfolio Acquiring Portfolio AST T. Rowe Price Large-Cap Value Portfolio On the Effective Date, the Target Portfolio will no longer be available under your annuity contract, and any Account Value allocated to the Subaccount investing in the Target Portfolio will be transferred to the Sub-account investing in the Acquiring Portfolio. This transfer will be made by replacing your contract s units of the Sub-account investing in the Target Portfolio with units of the Sub-account investing in the Acquiring Portfolio based on the unit value of each Portfolio at the time of the merger. The annual expenses for the AST T. Rowe Price Large-Cap Value Portfolio for the year ended December 31, 2017, as revised on July 1, 2018, are shown below. UNDERLYING MUTUAL FUND PORTFOLIO ANNUAL EXPENSES (as a percentage of the average net assets of the underlying Portfolios) FUNDS Management Fees Other Expenses Distribution (12b-1) Fees Dividend Expense on Short Sales Broker Fees and Expenses on Short Sales Acquired Portfolio Fees & Expenses Total Annual Portfolio Operating Expenses Fee Waiver or Expense Reimbursement Net Annual Fund Operating Expenses AST T. Rowe Price Large-Cap Value Portfolio* 0.67% 0.02% 0.25% 0.00% 0.00% 0.00% 0.94% 0.04% 0.90% *AST T. Rowe Price Large-Cap Value Portfolio The Manager has contractually agreed to waive 0.040% of its investment management fee through June 30, 2019. This arrangement may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. After the Effective Date, you should refer to the table captioned Underlying Mutual Fund Portfolio Annual Expenses in the Summary of Contract Fees and Expenses section of the Prospectus dated April 29, 2019 for the current information. GENPRODSUP13

In the Investment Options section of the Prospectus, information pertaining to the AST T. Rowe Price Large-Cap Value Portfolio is as follows: PORTFOLIO NAME INVESTMENT OBJECTIVE(S) PORTFOLIO ADVISER/SUBADVISER(S) AST T. Rowe Price Large-Cap Value Portfolio Seeks maximum growth of capital by investing primarily in the value stocks of larger companies. T. Rowe Price Associates, Inc. After the Effective Date, you should refer to the Investment Options section of the Prospectus dated April 29, 2019 for current information. Please note that you have the ability to transfer Account Value out of the Target Portfolio into an investment option available under your annuity contract any time prior to the Effective Date. Such transfers will be free of charge and will not count as one of your annual free transfers under your annuity contract. Also, for a period of 60 days after the Effective Date, any Account Value that was transferred to the Acquiring Portfolio as a result of the merger can be transferred into an investment option available under your annuity contract free of charge and will not count as one of your annual free transfers. It is important to note that any investment option into which you make your transfer will be subject to the transfer limitations described in your Prospectus. Please refer to your Prospectus for detailed information about investment options. After the Effective Date, the Target Portfolio will no longer exist and, unless you instruct us otherwise, any outstanding instruction you have on file with us that designates the Target Portfolio will be deemed an instruction for the Acquiring Portfolio. This includes, but is not limited to, Systematic Withdrawals and Dollar Cost Averaging. You may wish to consult with your financial professional to determine if your existing allocation instructions should be changed before or after the Effective Date. THIS SUPPLEMENT SHOULD BE READ AND RETAINED FOR FUTURE REFERENCE. GENPRODSUP13

PRUCO LIFE INSURANCE COMPANY PRUCO LIFE FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUCO LIFE INSURANCE COMPANY OF NEW JERSEY PRUCO LIFE OF NEW JERSEY FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION VARIABLE ACCOUNT B Supplement dated December 31, 2018 to Prospectuses dated April 30, 2018 This Supplement should be read in conjunction with the current Prospectus for your Annuity and should be retained for future reference. This Supplement is intended to update certain information in the Prospectus for the variable annuity you own and is not intended to be a prospectus or offer for any other variable annuity that you do not own. Defined terms used herein and not otherwise defined herein shall have the meanings given to them in the Prospectuses and Statements of Additional Information. Please check your Annuity Prospectus to determine which of the following changes affect the Annuity that you own. If you would like another copy of the current Annuity Prospectus, please call us at 1-888-PRU-2888. This Supplement describes a new portfolio of Advanced Series Trust ( AST ). In addition, effective on or about January 2, 2019, the AST Bond Portfolio 2018 will be closed and liquidated and, as a result, all references to the AST Bond Portfolio 2018 will be deleted from the Prospectus. New AST Portfolio AST Bond Portfolio 2030 (the Portfolio ). Effective on or about January 2, 2019, a variable investment option that invests in this Portfolio will be added to your Annuity. Please note, however, that the investment option is not available for the allocation of Purchase Payments or for transfers either incoming or outgoing. This Portfolio is available only with certain optional living benefits. The inside front cover of the Prospectus is hereby amended to include the name of this new Portfolio under Investment Options. In conjunction with the changes described above, the table captioned Underlying Mutual Fund Portfolio Annual Expenses in the Summary of Contract Fees and Charges section of the Prospectus is revised to add the following information: UNDERLYING MUTUAL FUND PORTFOLIO ANNUAL EXPENSES (as a percentage of the average net assets of the underlying Portfolios) FUNDS Management Fees Other Expenses Distribution (12b-1) Fees Dividend Expense on Short Sales Broker Fees and Expenses on Short Sales Acquired Portfolio Fees & Expenses Total Annual Portfolio Operating Expenses Fee Waiver or Expense Reimbursement Net Annual Fund Operating Expenses AST Bond Portfolio 2030 1 0.47% 0.08% 2 0.25 % 0.00% 0.00% 0.00% 0.80% 0.00% 0.80% 1 The Portfolio will commence operations on or about January 2, 2019. 2 Other expenses (which include expenses for accounting and valuation services, custodian fees, audit fees, legal fees, transfer agency fees, fees paid to Independent Trustees, and certain other miscellaneous items) are estimated. Estimate based in part on assumed average daily net assets of $200 million for the Portfolio for the fiscal period ending December 31, 2019. GENPRODSUP9

In the Investment Options section of the Prospectus, we add the following summary description for the Portfolio to the table below as follows: AST Bond Portfolio 2030 PORTFOLIO NAME INVESTMENT OBJECTIVE(S) Seeks the highest total return for a specific period of time, consistent with the preservation of capital and liquidity needs. Total return is comprised of current income and capital appreciation. PORTFOLIO ADVISER/SUBADVISER(S) PGIM Fixed Income THIS SUPPLEMENT SHOULD BE READ AND RETAINED FOR FUTURE REFERENCE GENPRODSUP9

PRUCO LIFE INSURANCE COMPANY PRUCO LIFE FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUCO LIFE INSURANCE COMPANY OF NEW JERSEY PRUCO LIFE OF NEW JERSEY FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION VARIABLE ACCOUNT B Supplement dated August 9, 2018 to Prospectuses dated April 30, 2018 This Supplement should be read in conjunction with the current Prospectus for your Annuity and should be retained for future reference. This Supplement is intended to update certain information in the Prospectus for the variable annuity you own and is not intended to be a prospectus or offer for any other variable annuity that you do not own. Defined terms used herein and not otherwise defined herein shall have the meanings given to them in the Prospectuses and Statements of Additional Information. This Supplement contains information about changes for certain Portfolios of the Advanced Series Trust available through your Annuity. Please check your Annuity Prospectus to determine which of the following changes affect the Annuity that you own. If you would like another copy of the current Annuity Prospectus, please call us at 1-888-PRU-2888. AST Goldman Sachs Strategic Income Portfolio Subadviser Change and Name Change: The Board of Trustees of Advanced Series Trust approved (i) replacing Goldman Sachs Asset Management, L.P. as a subadviser to the AST Goldman Sachs Strategic Income Portfolio with Pacific Investment Management Company, LLC, and (ii) changing the name of the Portfolio to the AST PIMCO Dynamic Bond Portfolio. These changes are expected to become effective on or about September 17, 2018. The annual expenses for the AST PIMCO Dynamic Bond Portfolio are shown below. The table captioned Underlying Mutual Fund Portfolio Annual Expenses in the Summary of Contract Fees and Expenses section of the Prospectus is as follows with respect to the Portfolio shown below: UNDERLYING MUTUAL FUND PORTFOLIO ANNUAL EXPENSES (as a percentage of the average daily net assets of the underlying Portfolios) FUNDS Management Fees Other Expenses Distribution (12b-1) Fees Dividend Expense on Short Sales Broker Fees and Expenses on Short Sales Acquired Portfolio Fees & Expenses Total Annual Portfolio Operating Expenses Fee Waiver or Expense Reimbursement AST PIMCO Dynamic Bond Portfolio 0.71% 0.09% 0.25% 0.00% 0.00% 0.00% 1.05% 0.00% 1.05% Net Annual Fund Operating Expenses In the Investment Options section of the Prospectus, information pertaining to the AST PIMCO Dynamic Bond Portfolio is as follows: PORTFOLIO INVESTMENT PORTFOLIO NAME OBJECTIVE(S) ADVISER(S)/SUBADVISER(S) AST PIMCO Dynamic Bond Portfolio Seeks total return. Pacific Investment Management Company, LLC AST Lord Abbett Core Fixed Income Portfolio Merger: Effective as of the close of business on September 14, 2018 (the Effective Date ), the AST Lord Abbett Core Fixed Income Portfolio (the Target Portfolio ) will be merged into the AST Western Asset Core Plus Bond Portfolio (the Acquiring Portfolio ) as noted below. All references to the AST Lord Abbett Core Fixed Income Portfolio in your Annuity Prospectus should be disregarded after the Effective Date. AST Lord Abbett Core Fixed Income Portfolio Target Portfolio AST Western Asset Core Plus Bond Portfolio Acquiring Portfolio GENPRODSUP3

On the Effective Date, the Target Portfolio will no longer be available under your annuity contract, and any Account Value allocated to the Sub-account investing in the Target Portfolio will be transferred to the Sub-account investing in the Acquiring Portfolio. This transfer will be made by replacing your contract s units of the Sub-account investing in the Target Portfolio with units of the Sub-account investing in the Acquiring Portfolio based on the unit value of each Portfolio at the time of the merger. The annual expenses for the AST Western Asset Core Plus Bond Portfolio are shown below. The table captioned Underlying Mutual Fund Portfolio Annual Expenses in the Summary of Contract Fees and Expenses section of the Prospectus is as follows with respect to the Portfolio shown below: UNDERLYING MUTUAL FUND PORTFOLIO ANNUAL EXPENSES (as a percentage of the average daily net assets of the underlying Portfolios) FUNDS Management Fees Other Expenses Distribution (12b-1) Fees Dividend Expense on Short Sales Broker Fees and Expenses on Short Sales Acquired Portfolio Fees & Expenses Total Annual Portfolio Operating Expenses Fee Waiver or Expense Reimbursement Net Annual Fund Operating Expenses AST Western Asset Core Plus Bond Portfolio 0.51% 0.02% 0.25% 0.00% 0.00% 0.00% 0.78% 0.00% 0.78% In the Investment Options section of the Prospectus, information pertaining to the AST Western Asset Core Plus Bond Portfolio is as follows: PORTFOLIO NAME AST Western Asset Core Plus Bond Portfolio INVESTMENT OBJECTIVE(S) Seeks to maximize total return, consistent with prudent investment management and liquidity needs, by investing to obtain the average duration specified for the Portfolio. PORTFOLIO ADVISER(S)/SUBADVISER(S) Western Asset Management Company Western Asset Management Company Limited Please note that you have the ability to transfer Account Value out of the Target Portfolio into an investment option available under your annuity contract any time prior to the Effective Date. Such transfers will be free of charge and will not count as one of your annual free transfers under your annuity contract. Also, for a period of 60 days after the Effective Date, any Account Value that was transferred to the Acquiring Portfolio as a result of the merger can be transferred into an investment option available under your annuity contract free of charge and will not count as one of your annual free transfers. It is important to note that any investment option into which you make your transfer will be subject to the transfer limitations described in your Prospectus. Please refer to your Prospectus for detailed information about investment options. After the Effective Date, the Target Portfolio will no longer exist and, unless you instruct us otherwise, any outstanding instruction you have on file with us that designates the Target Portfolio will be deemed an instruction for the Acquiring Portfolio. This includes, but is not limited to, Systematic Withdrawals and Dollar Cost Averaging. You may wish to consult with your financial professional to determine if your existing allocation instructions should be changed before or after the Effective Date. THIS SUPPLEMENT SHOULD BE READ AND RETAINED FOR FUTURE REFERENCE. GENPRODSUP3

PRUCO LIFE INSURANCE COMPANY PRUCO LIFE FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUCO LIFE INSURANCE COMPANY OF NEW JERSEY PRUCO LIFE OF NEW JERSEY FLEXIBLE PREMIUM VARIABLE ANNUITY ACCOUNT PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION PRUDENTIAL ANNUITIES LIFE ASSURANCE CORPORATION VARIABLE ACCOUNT B Supplement dated July 1, 2018 to Prospectuses dated April 30, 2018 This Supplement should be read in conjunction with the current Prospectus for your Annuity and should be retained for future reference. This Supplement is intended to update certain information in the Prospectus for the variable annuity you own and is not intended to be a prospectus or offer for any other variable annuity that you do not own. Defined terms used herein and not otherwise defined herein shall have the meanings given to them in the Prospectuses and Statements of Additional Information. This Supplement contains information about changes, effective July 1, 2018, to the management fees, or fee waivers or expense reimbursements, and total expenses for certain Portfolios of the Advanced Series Trust available through your Annuity and updates other information in the prospectus for your Annuity. Please check your Annuity Prospectus to determine which of the following changes affect the Annuity that you own. If you would like another copy of the current Annuity Prospectus, please call us at 1-888-PRU-2888. : The table captioned Underlying Mutual Fund Portfolio Annual Expenses in the Summary of Contract Fees and Charges section of the Prospectus is revised as follows with respect to the Portfolios shown below: UNDERLYING PORTFOLIO ANNUAL EXPENSES (as a percentage of the average daily net assets of the underlying Portfolios) Distribution (12b-1) Fees Dividend Expense on Short Sales Broker Fees and Expenses on Short Sales Acquired Portfolio Fees & Expenses Total Annual Portfolio Operating Expenses Fee Waiver or Expense Reimbursement Net Annual Fund Operating Expenses FUNDS Management Fees Other Expenses AST AQR Large-Cap Portfolio* 0.56% 0.01% 0.25% 0.00% 0.00% 0.00% 0.82% 0.01% 0.81% AST Cohen & Steers Realty Portfolio* 0.82% 0.03% 0.25% 0.00% 0.00% 0.00% 1.10% 0.05% 1.05% AST Goldman Sachs Large-Cap Value Portfolio* 0.56% 0.01% 0.25% 0.00% 0.00% 0.00% 0.82% 0.03% 0.79% AST Goldman Sachs Multi-Asset Portfolio* 0.76% 0.06% 0.25% 0.00% 0.00% 0.01% 1.08% 0.14% 0.94% AST Government Money Market Portfolio 0.30% 0.02% 0.25% 0.00% 0.00% 0.00% 0.57% 0.00% 0.57% AST QMA Large-Cap Portfolio* 0.55% 0.02% 0.25% 0.00% 0.00% 0.00% 0.82% 0.02% 0.80% AST T. Rowe Price Large-Cap Value Portfolio* 0.67% 0.02% 0.25% 0.00% 0.00% 0.00% 0.94% 0.04% 0.90% *See notes immediately below for important information about this fund. AST AQR Large-Cap Portfolio The Manager has contractually agreed to waive 0.007% of its investment management fee through June 30, 2019. This arrangement may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. AST Cohen & Steers Realty Portfolio The Manager has contractually agreed to waive 0.052% of its investment management fee through June 30, 2019. This arrangement may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. AST Goldman Sachs Large-Cap Value Portfolio The Manager has contractually agreed to waive 0.013% of its investment management fee through June 30, 2019. The Manager has also contractually agreed to waive an additional 0.015% of its investment management fee through June 30, 2019. These arrangements may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. GENPRODSUP2

AST Goldman Sachs Multi-Asset Portfolio The Manager has contractually agreed to waive 0.120% of its investment management fee through June 30, 2019. In addition, the Manager has contractually agreed to waive a portion of its investment management fee and/or reimburse certain expenses of the Portfolio so that the Portfolio's investment management fee plus other expenses (exclusive, in all cases of, interest, brokerage, taxes (such as income and foreign withholding taxes, stamp duty and deferred tax expenses), extraordinary expenses, acquired fund fees and expenses, and certain other Portfolio expenses such as dividend and interest expense and broker charges on short sales) do not exceed 0.930% of the Portfolio's average daily net assets through June 30, 2019. These arrangements may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. Expenses waived/reimbursed by the Manager may be recouped by the Manager within the same fiscal year during which such waiver/reimbursement is made if such recoupment can be realized without exceeding the expense limit in effect at the time of the recoupment for that fiscal year. The Manager has also contractually agreed to waive a portion of its investment management fee equal to the management fee of any acquired fund managed or subadvised by Goldman Sachs Asset Management, L.P. AST QMA Large-Cap Portfolio The Manager has contractually agreed to waive 0.015% of its investment management fee through June 30, 2019. This arrangement may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. AST T. Rowe Price Large-Cap Value Portfolio The Manager has contractually agreed to waive 0.040% of its investment management fee through June 30, 2019. This arrangement may not be terminated or modified prior to June 30, 2019 without the prior approval of the Trust s Board of Trustees. Summary of Contract Fees and Charges - Minimum/Maximum: Effective July 1, 2018, for those prospectuses which the AST Government Money Market Portfolio represents the minimum total underlying portfolio operating expense, the Total Annual Underlying Portfolio Operating Expenses table is amended to reflect the reduction in the minimum operating expense from 0.59% to 0.57% as follows: The following table provides the range (minimum and maximum) of the total annual expenses for the underlying mutual funds ( Portfolios ) as of July 1, 2018 before any contractual waivers and expense reimbursements. Each figure is stated as a percentage of the underlying Portfolio s average daily net assets. TOTAL ANNUAL UNDERLYING PORTFOLIO OPERATING EXPENSES MINIMUM MAXIMUM Total Underlying Portfolio Operating Expense 0.57% 2.42% Subadviser Change: AST J.P. Morgan Global Thematic Portfolio. Security Capital Research & Management Incorporated is removed as a subadviser to the Portfolio. Other Information: For Annuities issued by Pruco Life Insurance Company: In the OTHER INFORMATION - Fees and Payments Received by Pruco Life section of the Prospectus, the fourth paragraph is restated as follows: In addition, an adviser or subadviser of a Portfolio or a distributor of the Annuity (not the Portfolios) may also compensate us by providing reimbursement, defraying the costs of, or paying directly for, among other things, marketing and/or administrative services and/or other services they provide in connection with the Annuity. These services may include, but are not limited to: sponsoring or co-sponsoring various promotional, educational or marketing meetings and seminars attended by distributors, wholesalers, and/or broker dealer firms registered representatives, and creating marketing material discussing the Annuity, available options, and underlying Portfolios. The amounts paid depend on the nature of the meetings, the number of meetings attended by the adviser, subadviser, or distributor, the number of participants and attendees at the meetings, the costs expected to be incurred, and the level of the adviser s, subadviser s or distributor s participation. These payments or reimbursements may not be offered by all advisers, subadvisers, or distributors and the amounts of such payments may vary between and among each adviser, subadviser, and distributor depending on their respective participation. We may also consider these payments and reimbursements when selecting the Portfolios available under the Annuity. For the annual period ended December 31, 2017, with regard to the total annual amounts that were paid (or as to which a payment amount was accrued) under the kinds of arrangements described in this paragraph, the amounts for any particular adviser, subadviser or distributor ranged from $5,000 to $556,437. These amounts relate to all individual variable annuity contracts issued by Pruco Life or its affiliates, not only the Annuity covered by this prospectus. GENPRODSUP2

For Annuities issued by Pruco Life Insurance Company of New Jersey: In the OTHER INFORMATION - Fees and Payments Received by Pruco Life of New Jersey section of the Prospectus, the fourth paragraph is restated as follows: In addition, an adviser or subadviser of a Portfolio or a distributor of the Annuity (not the Portfolios) may also compensate us by providing reimbursement, defraying the costs of, or paying directly for, among other things, marketing and/or administrative services and/or other services they provide in connection with the Annuity. These services may include, but are not limited to: sponsoring or co-sponsoring various promotional, educational or marketing meetings and seminars attended by distributors, wholesalers, and/or broker dealer firms registered representatives, and creating marketing material discussing the Annuity, available options, and underlying Portfolios. The amounts paid depend on the nature of the meetings, the number of meetings attended by the adviser, subadviser, or distributor, the number of participants and attendees at the meetings, the costs expected to be incurred, and the level of the adviser s, subadviser s or distributor s participation. These payments or reimbursements may not be offered by all advisers, subadvisers, or distributors and the amounts of such payments may vary between and among each adviser, subadviser, and distributor depending on their respective participation. We may also consider these payments and reimbursements when selecting the Portfolios available under the Annuity. For the annual period ended December 31, 2017, with regard to the total annual amounts that were paid (or as to which a payment amount was accrued) under the kinds of arrangements described in this paragraph, the amounts for any particular adviser, subadviser or distributor ranged from $5,000 to $556,437. These amounts relate to all individual variable annuity contracts issued by Pruco Life of New Jersey or its affiliates, not only the Annuity covered by this prospectus. For Annuities Issued by Prudential Annuities Life Assurance Corporation: In the GENERAL INFORMATION - Fees and Payments Received by Prudential Annuities section of the Prospectus, the fourth paragraph is restated as follows: In addition, an adviser or subadviser of a Portfolio or a distributor of the Annuity (not the Portfolios) may also compensate us by providing reimbursement, defraying the costs of, or paying directly for, among other things, marketing and/or administrative services and/or other services they provide in connection with the Annuity. These services may include, but are not limited to: sponsoring or co-sponsoring various promotional, educational or marketing meetings and seminars attended by distributors, wholesalers, and/or broker dealer firms registered representatives, and creating marketing material discussing the Annuity, available options, and underlying Portfolios. The amounts paid depend on the nature of the meetings, the number of meetings attended by the adviser, subadviser, or distributor, the number of participants and attendees at the meetings, the costs expected to be incurred, and the level of the adviser s, subadviser s or distributor s participation. These payments or reimbursements may not be offered by all advisers, subadvisers, or distributors and the amounts of such payments may vary between and among each adviser, subadviser, and distributor depending on their respective participation. We may also consider these payments and reimbursements when selecting the Portfolios available under the Annuity. For the annual period ended December 31, 2017, with regard to the total annual amounts that were paid (or as to which a payment amount was accrued) under the kinds of arrangements described in this paragraph, the amounts for any particular adviser, subadviser or distributor ranged from $5,000 to $556,437. These amounts relate to all individual variable annuity contracts issued by Prudential Annuities or its affiliates, not only the Annuity covered by this prospectus. Prudential Premier Retirement Variable Annuity For the following annuities issued by Pruco Life Insurance Company: (i) Prudential Premier Retirement Variable Annuity, Flexible Premium Deferred Annuity; (ii) Prudential Premier Retirement Variable Annuity, Flexible Premium Deferred Annuity Offering Highest Daily Lifetime Income v2.1 Optional Benefits; and (iii) Prudential Premier Retirement Variable Annuity, Flexible Premium Deferred Annuity Offering Highest Daily Lifetime Income v3.0 Optional Living Benefits and Legacy Protection Plus Optional Death Benefit: With respect to the Spousal Highest Daily Lifetime Income benefit, each designated life must be at least 50 years old when the benefit is elected. Accordingly, each instance where the age requirement of a designated life is indicated as at least 45 years old at the time of election is changed to at least 50 years old at the time of election. THIS SUPPLEMENT SHOULD BE READ AND RETAINED FOR FUTURE REFERENCE. GENPRODSUP2

PRUDENTIAL PREMIER ADVISOR SM VARIABLE ANNUITY SERIES ( ADVISOR SERIES ) (For Annuities issued on or after February 25, 2013) Flexible Premium Deferred Annuity Offering Highest Daily Lifetime Income v2.1 Optional Benefits PROSPECTUS: April 30, 2018 PRUCO LIFE INSURANCE COMPANY A Prudential Financial Company 751 Broad Street, Newark, NJ 07102-3777 This prospectus describes a flexible premium deferred annuity offered by Pruco Life Insurance Company ( Pruco Life ), which we refer to in this prospectus as the Annuity or the Advisor Series. This prospectus is being provided for informational or educational purposes only and does not take into account the investment objectives or financial situation of any client or prospective clients. The information is not intended as investment advice and is not a recommendation about managing or investing your retirement savings. Clients seeking information regarding their particular investment needs should contact a financial professional. The Annuity described in this prospectus is designed for investors who have hired an investment adviser to provide advice about allocating Account Value within the Annuity. The Annuity may be offered as an individual annuity contract or as an interest in a group annuity. The Annuity has different features and benefits that may be appropriate for you based on your financial situation, your age and how you intend to use the Annuity. Certain of the Investment Options and/or features may not be available in all states. Financial professionals may be compensated for the sale of the Annuity. Selling broker-dealer firms through which the Annuity is sold may not recommend all the benefits described in this prospectus. In addition, selling broker-dealer firms may decline to make available or may not recommend to customers certain of the optional features and/or benefits and Investment Options offered generally under the Annuity or may impose restrictions (e.g., a lower maximum issue age for certain optional benefits). Please speak to your financial professional for further details. The guarantees provided by the variable annuity contract and the optional benefits are the obligations of and subject to the claims paying ability of Pruco Life. Certain terms are capitalized in this prospectus. Those terms are either defined in the Glossary of Terms or in the context of the particular section. THE SUB-ACCOUNTS The Pruco Life Flexible Premium Variable Annuity Account is a Separate Account of Pruco Life, and is the investment vehicle in which your Purchase Payments invested in the Sub-accounts are held. Each Sub-account of the Pruco Life Flexible Premium Variable Annuity Account invests in an underlying mutual fund see the following page for a complete list of the Sub-accounts. Currently, Portfolios of Advanced Series Trust and ProFunds VP are being offered. Certain Sub-accounts are not available if you participate in an optional living benefit see Limitations With Optional Benefits later in this prospectus for details. PLEASE READ THIS PROSPECTUS This prospectus sets forth information about the Annuity that you should know before investing. Please read this prospectus and the current prospectus for the underlying mutual funds. Keep them for future reference. If you are purchasing the Annuity as a replacement for an existing variable annuity or variable life policy, or a fixed insurance policy, you should consider any surrender or penalty charges you may incur and any benefits you may also be forfeiting when replacing your existing coverage. Please note that if you are investing in this Annuity through a taxadvantaged retirement plan (such as an Individual Retirement Account or 401(k) plan), you will get no additional tax advantage through the Annuity itself. OTHER CONTRACTS We offer a variety of fixed and variable annuity contracts. They may offer features, including investment options, and have fees and charges, that are different from the annuity contracts offered by this prospectus. Not every annuity contract we issue is offered through every selling broker-dealer firm. Upon request, your financial professional can show you information regarding other Pruco Life annuity contracts that he or she distributes. You can also contact us to find out more about the availability of any of the Pruco Life annuity contracts. You should work with your financial professional to decide whether this annuity contract is appropriate for you based on a thorough analysis of your particular needs, financial objectives, investment goals, time horizons and risk tolerance. AVAILABLE INFORMATION We have also filed a Statement of Additional Information dated the same date as this prospectus that is available from us, without charge, upon your request. The contents of the Statement of Additional Information are described at the end of this prospectus see Table of Contents. The Statement of Additional Information is incorporated by reference into this prospectus. This prospectus is part of the registration statement we filed with the SEC regarding this offering. Additional information on us and this offering is available in the registration statement and the exhibits thereto. You may review and obtain copies of these materials at no cost to you by contacting us. These documents, as well as documents incorporated by reference, may also be obtained through the SEC s Internet Website (www.sec.gov) for this registration statement as well as for other registrants that file electronically with the SEC. Please see How to Contact Us later in this prospectus for our Service Office address. In compliance with U.S. law, Pruco Life delivers this prospectus to current contract owners that reside outside of the United States. In addition, we may not market or offer benefits, features or enhancements to prospective or current contract owners while outside of the United States. PPADV21DPROS

This Annuity is NOT a deposit or obligation of, or issued, guaranteed or endorsed by, any bank, and is NOT insured or guaranteed by the U.S. government, the Federal Deposit Insurance Corporation (FDIC), the Federal Reserve Board or any other agency. An investment in an annuity involves investment risks, including possible loss of value, even with respect to amounts allocated to the AST Government Money Market Sub-account. THIS SECURITY HAS NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION NOR HAS THE COMMISSION OR ANY STATE SECURITIES COMMISSION PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE. PRUDENTIAL, PRUDENTIAL FINANCIAL, PRUDENTIAL ANNUITIES AND THE ROCK LOGO ARE SERVICEMARKS OF THE PRUDENTIAL INSURANCE COMPANY OF AMERICA AND ITS AFFILIATES. OTHER PROPRIETARY PRUDENTIAL MARKS MAY BE DESIGNATED AS SUCH THROUGH USE OF THE SM OR SYMBOLS. FOR FURTHER INFORMATION CALL: 1-888-PRU-2888 OR GO TO OUR WEBSITE AT WWW.PRUDENTIALANNUITIES.COM Prospectus Dated: April 30, 2018 Statement of Additional Information Dated: April 30, 2018

VARIABLE INVESTMENT OPTIONS Advanced Series Trust AST Academic Strategies Asset Allocation Portfolio 1 AST Advanced Strategies Portfolio 1 AST AQR Emerging Markets Equity Portfolio AST AQR Large-Cap Portfolio AST Balanced Asset Allocation Portfolio 1 AST BlackRock Global Strategies Portfolio 1 AST BlackRock Low Duration Bond Portfolio AST BlackRock/Loomis Sayles Bond Portfolio AST Capital Growth Asset Allocation Portfolio 1 AST ClearBridge Dividend Growth Portfolio AST Cohen & Steers Realty Portfolio AST Fidelity Institutional AM SM Quantitative Portfolio 1,2 AST Global Real Estate Portfolio AST Goldman Sachs Large-Cap Value Portfolio AST Goldman Sachs Mid-Cap Growth Portfolio AST Goldman Sachs Multi-Asset Portfolio 1 AST Goldman Sachs Small-Cap Value Portfolio AST Government Money Market AST High Yield Portfolio AST Hotchkis & Wiley Large-Cap Value Portfolio AST International Growth Portfolio AST International Value Portfolio AST Investment Grade Bond Portfolio 3 AST J.P. Morgan Global Thematic Portfolio 1 AST J.P. Morgan International Equity Portfolio AST J.P. Morgan Strategic Opportunities Portfolio 1 AST Jennison Large-Cap Growth Portfolio AST Legg Mason Diversified Growth Portfolio 1 AST Loomis Sayles Large-Cap Growth Portfolio AST Lord Abbett Core Fixed Income Portfolio AST Managed Alternatives Portfolio AST MFS Global Equity Portfolio AST MFS Growth Portfolio AST MFS Large-Cap Value Portfolio AST Morgan Stanley Multi-Asset Portfolio AST Neuberger Berman Long/Short Portfolio AST Neuberger Berman/LSV Mid-Cap Value Portfolio AST New Discovery Asset Allocation Portfolio 1 AST Parametric Emerging Markets Equity Portfolio AST Preservation Asset Allocation Portfolio 1 AST Prudential Core Bond Portfolio AST Prudential Growth Allocation Portfolio 1 AST QMA Large-Cap Portfolio AST QMA US Equity Alpha Portfolio AST Quantitative Modeling Portfolio AST RCM World Trends Portfolio 1 AST Small-Cap Growth Opportunities Portfolio AST Small-Cap Growth Portfolio AST Small-Cap Value Portfolio AST T. Rowe Price Asset Allocation Portfolio 1 AST T. Rowe Price Growth Opportunities Portfolio 1 AST T. Rowe Price Large-Cap Growth Portfolio AST T. Rowe Price Large-Cap Value Portfolio AST T. Rowe Price Natural Resources Portfolio AST Templeton Global Bond Portfolio AST WEDGE Capital Mid-Cap Value Portfolio AST Wellington Management Hedged Equity Portfolio 1 AST Wellington Management Real Total Return Portfolio AST Western Asset Core Plus Bond Portfolio AST Western Asset Emerging Markets Debt Portfolio ProFunds VP Portfolios Consumer Goods Consumer Services Financials Health Care Industrials Large-Cap Growth Large-Cap Value Mid-Cap Growth Mid-Cap Value Real Estate Small-Cap Growth Small-Cap Value Telecommunications Utilities Prudential Series Funds PSF Small Capitalization Stock Portfolio PSF Stock Index Portfolio (1) (2) (3) These are the only variable investment options available to you if you select one of the optional living benefits. Fidelity Institutional AM is a service mark of FMR LLC. Used with permission. The AST Investment Grade Bond variable investment option is not available for allocation of Purchase Payments or contract owner transfers.

CONTENTS GLOSSARY OF TERMS 1 SUMMARY OF CONTRACT FEES AND CHARGES 3 EXPENSE EXAMPLES 10 SUMMARY 11 INVESTMENT OPTIONS 13 VARIABLE INVESTMENT OPTIONS 13 LIMITATIONS WITH OPTIONAL BENEFITS 17 MARKET VALUE ADJUSTMENT OPTIONS 18 RATES FOR MVA OPTIONS 18 MARKET VALUE ADJUSTMENT 18 LONG-TERM MVA OPTIONS 19 DCA MVA OPTIONS 19 GUARANTEE PERIOD TERMINATION 19 FEES, CHARGES AND DEDUCTIONS 20 MVA OPTION CHARGES 21 ANNUITY PAYMENT OPTION CHARGES 21 EXCEPTIONS/REDUCTIONS TO FEES AND CHARGES 21 PURCHASING YOUR ANNUITY 22 REQUIREMENTS FOR PURCHASING THE ANNUITY 22 DESIGNATION OF OWNER, ANNUITANT AND BENEFICIARY 23 RIGHT TO CANCEL 24 SCHEDULED PAYMENTS DIRECTLY FROM A BANK ACCOUNT 25 SALARY REDUCTION PROGRAMS 25 MANAGING YOUR ANNUITY 26 CHANGE OF OWNER, ANNUITANT AND BENEFICIARY DESIGNATIONS 26 MANAGING YOUR ACCOUNT VALUE 28 DOLLAR COST AVERAGING PROGRAMS 28 6 OR 12 MONTH DOLLAR COST AVERAGING PROGRAM (THE 6 OR 12 MONTH DCA PROGRAM) 28 AUTOMATIC REBALANCING PROGRAMS 29 AUTHORIZATION OF A THIRD PARTY INVESTMENT ADVISER TO MANAGE MY ACCOUNT 29 FINANCIAL PROFESSIONAL PERMISSION TO FORWARD TRANSACTION 30 RESTRICTIONS ON TRANSFERS BETWEEN INVESTMENT OPTIONS 30 ACCESS TO ACCOUNT VALUE 32 TYPES OF DISTRIBUTIONS AVAILABLE TO YOU 32 TAX IMPLICATIONS FOR DISTRIBUTIONS FROM NONQUALIFIED ANNUITIES 32 SYSTEMATIC WITHDRAWALS FROM MY ANNUITY DURING THE ACCUMULATION PERIOD 32 SYSTEMATIC WITHDRAWALS UNDER SECTIONS 72(t)/72(q) OF THE INTERNAL REVENUE CODE 33 REQUIRED MINIMUM DISTRIBUTIONS 33 SURRENDERS 34 SURRENDER VALUE 34 ANNUITY OPTIONS 35 LIVING BENEFITS 37 HIGHEST DAILY LIFETIME INCOME v2.1 BENEFIT 38 SPOUSAL HIGHEST DAILY LIFETIME INCOME v2.1 BENEFIT 48 HIGHEST DAILY LIFETIME INCOME v2.1 WITH HIGHEST DAILY DEATH BENEFIT 56 SPOUSAL HIGHEST DAILY LIFETIME INCOME v2.1 WITH HIGHEST DAILY DEATH BENEFIT 65 DEATH BENEFITS 75 TRIGGERS FOR PAYMENT OF THE DEATH BENEFIT 75 EXCEPTIONS TO AMOUNT OF DEATH BENEFIT 75 (i)

MINIMUM DEATH BENEFIT 76 SPOUSAL CONTINUATION OF ANNUITY 76 PAYMENT OF DEATH BENEFITS 76 BENEFICIARY CONTINUATION OPTION 77 VALUING YOUR INVESTMENT 79 VALUING THE SUB-ACCOUNTS 79 PROCESSING AND VALUING TRANSACTIONS 79 TAX CONSIDERATIONS 81 NONQUALIFIED ANNUITIES 81 QUALIFIED ANNUITIES 84 OTHER INFORMATION 90 PRUCO LIFE AND THE SEPARATE ACCOUNT 90 LEGAL STRUCTURE OF THE UNDERLYING PORTFOLIOS 92 DISTRIBUTION OF ANNUITIES OFFERED BY PRUCO LIFE 93 FINANCIAL STATEMENTS 95 INDEMNIFICATION 95 LEGAL PROCEEDINGS 96 CONTENTS OF THE STATEMENT OF ADDITIONAL INFORMATION 96 HOW TO CONTACT US 96 APPENDIX A - ACCUMULATION UNIT VALUES A-1 APPENDIX B - SPECIAL CONTRACT PROVISIONS FOR ANNUITIES ISSUED IN CERTAIN STATES B-1 APPENDIX C - MVA FORMULAS C-1 APPENDIX D - FORMULA FOR HIGHEST DAILY LIFETIME INCOME v2.1 SUITE OF LIVING BENEFITS D-1 (ii)