Quarter 4: Clinical Trials where the Date Site Selected occurred in the last 12 months to 31/03/2017

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2016-2017 Quarter 4: Clinical where the Date Site Selected occurred in the last 12 months to 31/03/2017 Data is represented for the 219 providers of NHS services subject to the requirement for at least 4 quarters. the 2gether NHSFT - - - - 5 Boroughs Partnership NHSFT 2 1 50.0 1 Aintree University Hospital NHSFT 5 1 20.0 4 Airedale NHSFT 1 1 100.0 0 Alder Hey Children's NHSFT 6 2 33.3 4 Ashford and St. Peter's Hospitals NHSFT 3 0 0.0 3 Avon and Wiltshire Mental Health Partnership NHST 1 1 100.0 0 Barking, Havering and Redbridge University Hospitals NHST 5 0 0.0 5 Barnet, Enfield and Haringey Mental Health NHST 2 1 50.0 1 Barnsley Hospital NHSFT 2 0 0.0 2 Barts Health NHST 27 11 40.7 16 Basildon and Thurrock University Hospitals NHSFT 3 1 33.3 2 Bedford Hospital NHST 1 0 0.0 1 Berkshire Healthcare NHSFT 2 1 50.0 1 Birmingham and Solihull Mental Health NHSFT 1 0 0.0 1 Birmingham Children's Hospital NHSFT 5 1 20.0 4 Birmingham Community Healthcare NHSFT 1 1 100.0 0 Birmingham Women's NHSFT # # # # Black Country Partnership NHSFT 1 1 100.0 0 Blackpool Teaching Hospitals NHSFT 8 0 0.0 8 Bolton NHSFT 0 0-0 Bradford District Care NHSFT 1 1 100.0 0 Bradford Teaching Hospitals NHSFT 10 5 50.0 5 Brighton and Sussex University Hospitals NHST 7 4 57.1 3 Buckinghamshire Healthcare NHST 2 0 0.0 2 Burton Hospitals NHSFT 1 1 100.0 0 Calderdale and Huddersfield NHSFT 2 0 0.0 2 Cambridge University Hospitals NHSFT 18 5 27.8 13 Cambridgeshire and Peterborough NHSFT 0 0-0 Cambridgeshire Community Services NHST - - - - Camden and Islington NHSFT 1 1 100.0 0 Central and North West London NHSFT 3 1 33.3 2 Central Manchester University Hospitals NHSFT 20 20 100.0 0

the Chelsea and Westminster Hospital NHSFT # # # # Cheshire and Wirral Partnership NHSFT 0 0-0 Chesterfield Royal Hospital NHSFT 1 1 100.0 0 City Hospitals Sunderland NHSFT 2 1 50.0 1 Colchester Hospital University NHSFT 3 1 33.3 2 Cornwall Partnership NHSFT 2 1 50.0 1 Countess of Chester Hospital NHSFT 3 1 33.3 2 County Durham and Darlington NHSFT 0 0-0 Coventry and Warwickshire Partnership NHST 0 0-0 Croydon Health Services NHST 0 0-0 Cumbria Partnership NHSFT 2 1 50.0 1 Dartford and Gravesham NHST 0 0-0 Derby Teaching Hospitals NHSFT 7 1 14.3 6 Derbyshire Community Health Services NHST - - - - Derbyshire Healthcare NHSFT 1 0 0.0 1 Devon Partnership NHST 0 0-0 Doncaster and Bassetlaw Hospitals NHSFT 5 2 40.0 3 Dorset County Hospital NHSFT 1 0 0.0 1 Dorset Healthcare University NHSFT 2 2 100.0 0 East and North Hertfordshire NHST 9 1 11.1 8 East Cheshire NHST # # # # East Kent Hospitals University NHSFT 3 2 66.7 1 East Lancashire Hospitals NHST 2 2 100.0 0 East London NHSFT 6 6 100.0 0 East of England Ambulance Service NHST 0 0-0 East Sussex Healthcare NHST 1 0 0.0 1 Epsom and St Helier University Hospitals NHST 0 0-0 Frimley Health NHSFT 2 0 0.0 2 Gateshead Health NHSFT 2 1 50.0 1 George Eliot Hospital NHST 1 0 0.0 1 Gloucestershire Hospitals NHSFT 4 1 25.0 3 Great Ormond Street Hospital for Children NHSFT 4 2 50.0 2 Great Western Hospitals NHSFT 5 1 20.0 4 Greater Manchester Mental Health NHSFT 6 4 66.7 2 Guy's and St Thomas' NHSFT 43 19 44.2 24 Hampshire Hospitals NHSFT 1 0 0.0 1 Harrogate and District NHSFT # # # # Heart Of England NHSFT 5 0 0.0 5

the Hertfordshire Community NHST - - - - Hertfordshire Partnership University NHSFT 0 0-0 Hinchingbrooke Health Care NHST # # # # Homerton University Hospital NHSFT 0 0-0 Hull and East Yorkshire Hospitals NHST 21 3 14.3 18 Humber NHSFT 1 1 100.0 0 Imperial College Healthcare NHST 35 17 48.6 18 Ipswich Hospital NHST 2 1 50.0 1 Isle of Wight NHST # # # # James Paget University Hospitals NHSFT 1 0 0.0 1 Kent and Medway NHS and Social Care Partnership Trust 2 1 50.0 1 Kettering General Hospital NHSFT 1 0 0.0 1 King's College Hospital NHSFT 24 13 54.2 11 Lancashire Care NHSFT 0 0-0 Lancashire Teaching Hospitals NHSFT 2 1 50.0 1 Leeds and York Partnership NHSFT 2 0 0.0 2 Leeds Community Healthcare NHST 0 0-0 Leeds Teaching Hospitals NHST 19 15 78.9 4 Leicestershire Partnership NHST 1 1 100.0 0 Lewisham and Greenwich NHST 3 0 0.0 3 Lincolnshire Community Health Services NHST 0 0-0 Lincolnshire Partnership NHSFT - - - - Liverpool Heart and Chest Hospital NHSFT 3 1 33.3 2 Liverpool Women's NHSFT 0 0-0 London Ambulance Service NHST 0 0-0 London North West Healthcare NHST 4 4 100.0 0 Luton and Dunstable University Hospital NHSFT 0 0-0 Maidstone and Tunbridge Wells NHST 7 1 14.3 6 Medway NHSFT 3 2 66.7 1 Mersey Care NHSFT 0 0-0 Mid Cheshire Hospitals NHSFT 0 0-0 Mid Essex Hospital Services NHST 0 0-0 Mid Yorkshire Hospitals NHST 3 1 33.3 2 Milton Keynes University Hospital NHSFT 1 0 0.0 1 Moorfields Eye Hospital NHSFT 3 2 66.7 1 Norfolk and Norwich University Hospitals NHSFT 7 3 42.9 4 Norfolk and Suffolk NHSFT 0 0-0 Norfolk Community Health and Care NHST 1 1 100.0 0

the North Bristol NHST 10 3 30.0 7 North Cumbria University Hospitals NHST 0 0-0 North East Ambulance Service NHSFT 0 0-0 North East London NHSFT 3 3 100.0 0 North Essex Partnership University NHSFT 2 1 50.0 1 North Middlesex University Hospital NHST 1 0 0.0 1 North Staffordshire Combined Healthcare NHST 1 0 0.0 1 North Tees and Hartlepool NHSFT 1 1 100.0 0 Northampton General Hospital NHST 0 0-0 Northamptonshire Healthcare NHSFT 1 0 0.0 1 Northern Devon Healthcare NHST 3 0 0.0 3 Northern Lincolnshire and Goole NHSFT 0 0-0 Northumberland, Tyne and Wear NHSFT 0 0-0 Northumbria Healthcare NHSFT 4 3 75.0 1 Nottingham University Hospitals NHST 19 7 36.8 12 Nottinghamshire Healthcare NHSFT 3 3 100.0 0 Oxford Health NHSFT 4 4 100.0 0 Oxford University Hospitals NHSFT 40 37 92.5 3 Papworth Hospital NHSFT 9 1 11.1 8 Pennine Acute Hospitals NHST 2 2 100.0 0 Pennine Care NHSFT 3 3 100.0 0 Peterborough and Stamford Hospitals NHSFT 1 0 0.0 1 Plymouth Hospitals NHST 9 5 55.6 4 Poole Hospital NHSFT 1 0 0.0 1 Portsmouth Hospitals NHST 8 7 87.5 1 Queen Victoria Hospital NHSFT 1 1 100.0 0 Royal Berkshire NHSFT 5 0 0.0 5 Royal Brompton and Harefield NHSFT 18 5 27.8 13 Royal Cornwall Hospitals NHST 6 1 16.7 5 Royal Devon and Exeter NHSFT 8 6 75.0 2 Royal Free London NHSFT 18 2 11.1 16 Royal Liverpool and Broadgreen University Hospitals NHST 9 1 11.1 8 Royal National Orthopaedic Hospital NHST 0 0-0 Royal Surrey County Hospital NHSFT 8 2 25.0 6 Royal United Hospitals Bath NHSFT 7 2 28.6 5 Salford Royal NHSFT 9 3 33.3 6 Salisbury NHSFT 2 0 0.0 2 Sandwell and West Birmingham Hospitals NHST 5 1 20.0 4

the Sheffield Children's NHSFT 3 1 33.3 2 Sheffield Health and Social Care NHSFT 3 3 100.0 0 Sheffield Teaching Hospitals NHSFT 21 16 76.2 5 Sherwood Forest Hospitals NHSFT 6 1 16.7 5 Shrewsbury and Telford Hospital NHST 1 0 0.0 1 Solent NHST 3 2 66.7 1 Somerset Partnership NHSFT 0 0-0 South Central Ambulance Service NHSFT - - - - South Essex Partnership University NHSFT 0 0-0 South London and Maudsley NHSFT 9 5 55.6 4 South Staffordshire and Shropshire Healthcare NHSFT 0 0-0 South Tees Hospitals NHSFT 8 4 50.0 4 South Tyneside NHSFT 2 2 100.0 0 South Warwickshire NHSFT 0 0-0 South West Yorkshire Partnership NHSFT 3 1 33.3 2 Southend University Hospital NHSFT 2 0 0.0 2 Southern Health NHSFT 6 5 83.3 1 Southport and Ormskirk Hospital NHST - - - - St George's University Hospitals NHSFT 12 1 8.3 11 St Helen's and Knowsley Hospital Services NHST 2 1 50.0 1 Staffordshire and Stoke on Trent Partnership NHST 6 2 33.3 4 Stockport NHSFT 1 0 0.0 1 Surrey and Borders Partnership NHSFT 3 3 100.0 0 Surrey and Sussex Healthcare NHST 1 0 0.0 1 Sussex Community NHSFT 1 1 100.0 0 Sussex Partnership NHSFT 3 3 100.0 0 Tameside Hospital NHSFT - - - - Taunton and Somerset NHSFT 9 1 11.1 8 Tavistock and Portman NHSFT 1 1 100.0 0 Tees Esk and Wear Valleys NHSFT 1 1 100.0 0 The Christie NHSFT 16 9 56.3 7 The Clatterbridge Cancer Centre NHSFT # # # # The Dudley Group NHSFT 3 0 0.0 3 The Hillingdon Hospitals NHSFT 0 0-0 The Newcastle upon Tyne Hospitals NHSFT 29 12 41.4 17 The Princess Alexandra Hospital NHST 4 0 0.0 4 The Queen Elizabeth Hospital Kings Lynn NHSFT 3 0 0.0 3 The Robert Jones and Agnes Hunt Orthopaedic Hospital NHSFT 2 0 0.0 2

the The Rotherham NHSFT 1 0 0.0 1 The Royal Bournemouth and Christchurch Hospitals NHSFT 6 0 0.0 6 The Royal Marsden NHSFT 22 14 63.6 8 The Royal Orthopaedic Hospital NHSFT 0 0-0 The Royal Wolverhampton NHST 10 4 40.0 6 The Walton Centre NHSFT 2 0 0.0 2 The Whittington Hospital NHST 2 1 50.0 1 Torbay and South Devon NHSFT 2 0 0.0 2 United Lincolnshire Hospitals NHST 3 0 0.0 3 University College London Hospitals NHSFT 6 4 66.7 2 University Hospital of South Manchester NHSFT 7 1 14.3 6 University Hospital Southampton NHSFT 11 11 100.0 0 University Hospitals Birmingham NHSFT 14 13 92.9 1 University Hospitals Bristol NHSFT 11 7 63.6 4 University Hospitals Coventry and Warwickshire NHST 4 2 50.0 2 University Hospitals of Leicester NHST 22 11 50.0 11 University Hospitals of Morecambe Bay NHSFT 1 0 0.0 1 University Hospitals of North Midlands NHST 5 1 20.0 4 Walsall Healthcare NHST 0 0-0 Warrington and Halton Hospitals NHSFT 0 0-0 West Hertfordshire Hospitals NHST 2 1 50.0 1 West London Mental Health NHST 1 1 100.0 0 West Midlands Ambulance Service NHST - - - - West Suffolk NHSFT 0 0-0 Western Sussex Hospitals NHSFT 2 1 50.0 1 Weston Area Health NHST 0 0-0 Wirral University Teaching Hospital NHSFT 3 0 0.0 3 Worcestershire Acute Hospitals NHST 2 0 0.0 2 Worcestershire Health and Care NHST 0 0-0 Wrightington, Wigan and Leigh NHSFT 0 0-0 Wye Valley NHST 1 0 0.0 1 Yeovil District Hospital NHSFT 1 1 100.0 0 York Teaching Hospital NHSFT 0 0-0 Yorkshire Ambulance Service NHST - - - -

Data submitted by providers is adjusted to remove trials where NIHR accepts that the source of delay was not the provider of NHS services acting as the trial host (for example in the case of an extremely rare disease where relevant patients cannot be identified in time). Comparative performance against the 70 day benchmark to recruit the first patient into clinical trials The performance table includes adjusted data for all providers of NHS services who have been subject to the requirement for 4 quarters or more. The main comparative measure is the. There are a number of scenarios where this measure may be incalculable and the following convention will be adopted in these circumstances: Scenario Convention for presentation in the table The provider may have relevant activity to report for the period, but has failed to make a submission no return The table will be populated with a hash symbol (#) in each of the numeric/percentage columns (A-D) The provider has reported that there was no relevant activity for the period a nil return The table will be populated with a hyphen in each of the numeric/percentage columns (A-D) The provider reported relevant activity for the period, but all activity was excluded from the adjusted analysis no adjusted activity The table will be populated with zero in each numeric column (A, B and D) and a hyphen in the percentage column (C).