Celgene Patient Support Learn about financial help for IDHIFA

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Celgene Patient Support Learn about financial help for IDHIFA A Celgene Patient Support Specialist can help you and your loved ones understand the programs and services available to you.

CELGENE PATIENT SUPPORT We care about making sure you get the help you need to start your treatment Celgene Patient Support is here to help you and your loved ones understand the financial help that may be available for IDHIFA. How Celgene Patient Support can help Our Specialists are ready to help you and your family with: Understanding your insurance plan Learning about financial assistance that may help you pay for IDHIFA Obtaining information about organizations that may assist you with travel costs to and from your doctor s office Enrollment in Celgene Patient Support is simple choose the option that is best for you. Transportation assistance Independent third-party organizations* may be able to help with travel costs to and from your doctor s office, including gas, tolls, parking, and taxi, bus, or train fare Enroll online at www.celgenepatientsupport.com Call us at 1-800-931-8691, (translation services available) E-mail us at patientsupport@celgene.com or fax 1-800-822-2496 *Financial and medical eligibility requirements vary by organization. Erin Celgene Patient Support Specialist 2 3

INSURANCE TYPES What type of insurance do you have? Commercial insurance Programs that help with the cost of IDHIFA differ by the type of insurance you have. Even if you don t have insurance or enough coverage to pay for your medicine, financial help may be available. If you have commercial insurance, you may qualify for the Celgene Commercial Co-pay Program. This type of insurance is given by your employer or purchased on your own. It could also be part of your retirement package from an employer. If you are eligible, our co-pay program lowers your co-pay responsibility.* Learn more on page 5. I have Medicare, Medicaid, or other government-sponsored insurance We can provide you with information about independent third-party organizations that may be able to lower your co-pay responsibility. Learn more on page 9. COMMERCIAL OR PRIVATE INSURANCE I have commercial insurance If you qualify, your out-of-pocket co-pay responsibility will be $25 for IDHIFA. This program provides up to $10,000 per calendar year to help meet co-pay/co-insurance costs. Eligibility criteria include* Commercial or private insurance (including healthcare exchanges) that does not cover the full cost of the prescribed Celgene medicine Residence in the United States or US territory Patients with government healthcare insurance (for example, Medicare [Parts B, C, and D], Medicaid, Medigap, TriCare) are not eligible How to enroll Celgene Patient Support can enroll you in this program. I do not have health insurance or enough coverage to pay for my medicine We have a program that may be able to provide you with medicine at no cost. Learn more on page 10. I don t know what type of insurance I have Call your Specialist at 1-800-931-8691. * Other eligibility requirements and restrictions apply. Please see full Terms and Conditions on pages 6 and 7 of this brochure. 4 *Please see full Terms and Conditions for eligibility criteria on pages 6 and 7 of this brochure. Financial and medical eligibility requirements vary by organization. Patients must meet specified financial and eligibility requirements to qualify for assistance. 5

Celgene Commercial Co-pay Program Terms and Conditions CO-PAY PROGRAM TERMS AND CONDITIONS Eligibility Patients must meet the following criteria to enroll: Covered by commercial or private insurance Reside in the United States or a US territory Not participating in a federal or state-funded healthcare program, including, but not limited to, Medicare (Parts B, C, and D) or Medicaid, Medigap, CHAMPVA, DOD, or Tricare Program Timing If eligible, patients will be enrolled from the date of enrollment through the end of the then current calendar year CO-PAY PROGRAM TERMS AND CONDITIONS Program Benefits For Celgene oral hematology products, Celgene provides assistance to reduce the co-pay of eligible patients to $25 per prescription with a maximum benefit of $10,000 per enrollment period Patients are responsible for any costs that exceed the Program s $10,000 maximum The Program will not cover, and shall not be applied toward, the cost of any dosing procedure, any other healthcare provider service or supply charges or other treatment costs, or any costs associated with a hospital stay Additional Terms and Conditions of the Celgene Commercial Co-pay Program Patients, pharmacists, and healthcare providers must not seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through this Program. Patients must not seek reimbursement from any health savings, flexible spending, or other healthcare reimbursement accounts for the amount of assistance received from the Program Acceptance of this offer confirms that this offer is consistent with your insurance and that you will report the value of the co-pay assistance you receive, as may be required by your insurance provider Only valid in the United States and US territories; this offer is void where prohibited by law, taxed or restricted. Absent a change in Massachusetts law, effective July 1, 2019, Massachusetts residents will no longer be eligible to participate in this Program The Program benefits are nontransferable Acceptance of this Program is not conditioned on any past, present, or future purchase, including additional doses The Program cannot be combined with any other coupon, rebate, voucher, free trial, or similar offer The Program is not insurance Celgene reserves the right to rescind, revoke, or amend this Program at any time without notice 6 7

Your Specialist will get to know you, your specific needs, and your coverage situation. Medicare, Medicaid, or other government-sponsored insurance Your Specialist can provide you with information about independent third-party organizations* that may be able to help with the cost of your: Deductibles Co-payments/co-insurance Insurance premiums MEDICARE OR MEDICAID *Financial and medical eligibility requirements vary by organization. MEDICARE OR MEDICAID Jemell Celgene Patient Support Specialist 8 9

I do not have health insurance or enough coverage to pay for IDHIFA If you do not have health insurance or enough coverage to pay for IDHIFA, the Celgene Patient Assistance Program (PAP)* may be able to provide you with IDHIFA at no cost. PI Pocket Every time you call, you will speak to the same Specialist who will help identify the right support for you. To qualify, you must meet certain financial criteria. Your Specialist can tell you if you qualify. *Patients must meet specified financial and insurance eligibility criteria to qualify for assistance. UNINSURED Celgene Patient Support can also provide information about insurance coverage or other programs you may qualify for. Celgene Patient Support Specialist UNINSURED 10 Josephine 11

PI Pocket Enrollment is simple Our Specialists are professionals who are trained to help you understand your insurance coverage and find the resources you need to start your treatment. Enrollment in Celgene Patient Support is simple choose the option that is best for you. Enroll online at www.celgenepatientsupport.com Call us at 1-800-931-8691, (translation services available) E-mail us at patientsupport@celgene.com or fax 1-800-822-2496 IDHIFA and Celgene Patient Support are registered trademarks of Celgene Corporation. IDHIFA is licensed from Agios Pharmaceuticals, Inc. Other trademarks are the property of their respective owners. 2018 Celgene Corporation 12/18 US-IDH-18-0217