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Nimbus 9 STRATEGY HIGHLIGHTS Ticker: TRLGX CUSIP: 45775L408 As of September 30, 2018 Total Large-Cap Growth Assets: $222.6 billion 2 Total Strategy Assets: 1 $42.7 billion 2 Total Fund Assets: $18.3 billion 2 INVESTMENT APPROACH p Scrutinize both company- and industry-level fundamentals to identify companies with characteristics that support sustainable double-digit earnings growth. p Focus on high-quality earnings, strong free cash flow growth, shareholder-oriented management, and rational competitive environments. p Exploit differences between secular and cyclical trends. p Limit portfolio holdings to the most attractive growth opportunities across industries. p The fund is subject to the volatility inherent in common stock investing, and its share price may fluctuate more than a fund investing in non-growth oriented stocks. p The fund is nondiversified, meaning it may invest a greater portion of its assets in asingle issuer and own more of the issuer s voting securities than is permissible for a diversified fund. PORTFOLIO CONSTRUCTION p Typically 60-75 stock portfolio p Individual position sizes typically range +/- 1.00% to 4.00% relative to p Sector weights will vary from 0.5X to 3.0X for primary sectors relative to BENCHMARK p PORTFOLIO MANAGEMENT Taymour R. Tamaddon, CFA Lead Portfolio Manager p 15 years of investment experience; 14 years with T. Rowe Price. p M.B.A., Tuck School of Business at Dartmouth p B.S., Cornell University Larry J. Puglia, CFA, CPA Lead Portfolio Manager p 29 years of investment experience; 28 years with T. Rowe Price. p M.B.A., University of Virginia, Darden School of Business p B.B.A., University of Notre Dame Joseph B. Fath, CPA p 18 years of investment experience; 16 years with T. Rowe Price. p M.B.A., The Wharton School, University of Pennsylvania p B.S., University of Illinois David L. Rowlett, CFA p 15 years of investment experience; 10 years with T. Rowe Price. p M.B.A., University of North Carolina, Kenan-Flagler Business School p B.B.A., University of Georgia PORTFOLIO SPECIALISTS Ronald H. Taylor p 30 years of investment experience; 15 years with T. Rowe Price. p M.B.A., Harvard University p B.A., University of California, Los Angeles Craig S. Watson, CPA p 23 years of investment experience; 11 years with T. Rowe Price. p M.B.A., The Wharton School, University of Pennsylvania p B.S., Hampton University For a complete list of the members of the Fund s Investment Advisory Committee, please refer to the Fund s prospectus. 1 Includes a U.S.-registered mutual fund, a sub-fund of a Luxembourg domiciled SICAV, separate accounts, and subadvised portfolios. 2 Assets reported are as of June 30, 2018. FOR INVESTMENT PROFESSIONALS ONLY. NOT FOR FURTHER DISTRIBUTION. p T. ROWE PRICE 1

TOP 10 ISSUERS % of Fund Amazon.com 9.8% Alphabet 6.9 Microsoft 6.3 Boeing 4.8 Visa 4.7 Tencent Holdings 4.1 Booking Holdings 3.2 Facebook 2.9 UnitedHealth Group 2.9 Cigna 2.5 Total 46.3% SECTOR DIVERSIFICATION Over/Underweight 40% 30% 20% 10% 0% -10% -20% Info Tech Cons Disc Health Care Comm Svcs Indust & Bus Svcs Financials Utilities Cons Stpls Real Estate Materials Energy PORTFOLIO CHARACTERISTICS Fund Projected Earnings Growth Rate (IBES) 15.5% 14.8% Price to Earnings (12 Months Forward) 23.6X 22.4X Return on Equity (Last 12 Months excl. charges) 21.5% 25.6% Price to Book 9.0X 9.5X Investment Weighted Median Market Cap (mm) $126,754 $120,338 Investment Weighted Average Market Cap (mm) $336,897 $323,511 Number of Holdings 66 535 Top 20 Holdings as % of Total 64.4% 45.9% Portfolio Turnover 33.6% Active Share 59.8% Investment Weighted Median. Based on the fund s underlying holdings and is not a projection of future portfolio performance. Portfolio Turnover represents 1 year period ending 12/31/17. FOR INVESTMENT PROFESSIONALS ONLY. NOT FOR FURTHER DISTRIBUTION. p T. ROWE PRICE 2

PERFORMANCE Three Months Annualized 6.82% 19.70% 28.43% 22.68% 17.99% 16.70% 12.11% 9.17 17.09 26.30 20.55 16.58 14.31 10.67 Current performance may be lower or higher than the quoted past performance, which cannot guarantee future results. Share price, principal value, and return will vary, and you may have a gain or loss when you sell your shares. To obtain the most recent month-end performance or to request a prospectus or summary prospectus, which includes investment objectives, risks, fees, expenses, and other information that you should read and consider carefully before investing, please call 1-800-638-7780 or visit our website at troweprice.com. Total return figures include changes in principal value, reinvested dividends, and capital gain distributions. The Fund s expense ratio was 0.56% as of its most recent prospectus. Year-to- Date One Year Three Five Ten Fifteen FOR INVESTMENT PROFESSIONALS ONLY. NOT FOR FURTHER DISTRIBUTION. p T. ROWE PRICE 3

RISK/RETURN CHARACTERISTICS Five ended September 30, 2018 19 Information Ratio Sharpe Ratio Tracking Error R-Squared Beta Alpha 0.29 0.00 0.00% 1.44 1.56 0.85 1.00 1.08 1.00 0.12% 0.00% 4.84% -4-3 -2-1 0 1 2 3 4 5 6 7 Average Annual Return (%) 18 17 16 15 LCG. 9 10 11 12 13 14 Average Annual Standard Deviation (%) Past performance cannot guarantee future results. Figures are calculated using monthly data and are net of fees. FOR INVESTMENT PROFESSIONALS ONLY. NOT FOR FURTHER DISTRIBUTION. p T. ROWE PRICE 4

ADDITIONAL DISCLOSURES Portfolio Construction: There is no guarantee that the investment will remain within the anticipated ranges of exposure. Active Share is a holdings based measure of active management representing the percentage of a portfolio s holdings that differ from those in its benchmark. Compared to tracking error, which measures the standard deviation of the difference in a manager s returns versus the Benchmark returns, Active Share allows investors to get a clearer understanding of what a manager is doing to drive performance, rather than drawing conclusions from observed returns. The greater the difference between the asset composition of a product and its benchmark, the greater the active share is. Unless indicated otherwise the source of all data is T. Rowe Price. Source for Lipper data: Lipper Inc. Lipper Data (excluding Performance and Risk Return exhibits) is estimated by T. Rowe Price based on information provided by Lipper, Inc., and LionShares. T. Rowe Price identifies the funds that compose the Lipper index and builds an aggregate portfolio for the index based on each fund s holdings as provided by LionShares. Please note that the portfolio holdings for each fund within the index are based on the most recent public information that is available, and since the funds have different reporting periods, some of this information may not be current. Russell Investment Group is the source and owner of the trademarks, service marks and copyrights related to the Russell Indexes. Russell is a trademark of Russell Investment Group. The information shown does not reflect any ETFs that may be held in the portfolio. Source for Sector Diversification: T. Rowe Price uses the MSCI/S&P Global Industry Classification Standard (GICS) for sector and industry reporting. Each year, MSCI and S&P review the GICS structure. The last change occurred on September 28, 2018. The Telecommunications Services sector was expanded and renamed Communication Services. Some securities previously assigned to Information Technology or Consumer Discretionary were reclassified as Communication Services. T. Rowe Price will adhere to all future updates to GICS for prospective reporting. Diversification exhibits may not add to 100% due to exclusion or inclusion of cash. Certain numbers in this report may not equal stated totals due to rounding. Unless otherwise stated, data is as of the report date. This material has been prepared for informational purposes only. The views and opinions stated in this commentary are those of the portfolio managers listed as of the date indicated. These views and opinions are subject to change based on market or other conditions and may differ from those of other T. Rowe Price associates. Actual market and investment results may differ materially from expectations. 2018 T. Rowe Price. All rights reserved. T. ROWE PRICE, INVEST WITH CONFIDENCE, and the Bighorn Sheep design are, collectively and/or apart, trademarks or registered trademarks of T. Rowe Price Group, Inc. T. Rowe Price Investment Services, Inc., Distributor. 2016-US-28224 FOR INVESTMENT PROFESSIONALS ONLY. NOT FOR FURTHER DISTRIBUTION. p T. ROWE PRICE 5