Right care. Right time. Right place.

Right care. Right time. Right place. Amedisys Investor Presentation June 2016 0

Forward-looking Statements This presentation may include forward-looking statements as defined by the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based upon current expectations and assumptions about our business that are subject to a variety of risks and uncertainties that could cause actual results to differ materially from those described in this presentation. You should not rely on forward-looking statements as a prediction of future events. Additional information regarding factors that could cause actual results to differ materially from those discussed in any forward-looking statements are described in reports and registration statements we file with the SEC, including our Annual Report on Form 10-K and subsequent Quarterly Reports on Form 10-Q and Current Reports on Form 8-K, copies of which are available on the Amedisys internet website http://www.amedisys.com or by contacting the Amedisys Investor Relations department at (225) 292-2031. We disclaim any obligation to update any forward-looking statements or any changes in events, conditions or circumstances upon which any forward-looking statement may be based except as required by law. www.amedisys.com NASDAQ: AMED We encourage everyone to visit the Investors Section of our website at www.amedisys.com, where we have posted additional important information such as press releases, profiles concerning our business and clinical operations and control processes, and SEC filings. We intend to use our website to expedite public access to time-critical information regarding the Company in advance of or in lieu of distributing a press release or a filing with the SEC disclosing the same information. 1

Highlights and Summary Financial Results (Adjusted) 1Q 2016 (1) Year-over-Year Comparison Revenue Growth: +16% Amedisys Consolidated EBITDA: $24M EBITDA Margin: 6.9% EPS: $0.33 Cash Flow Cash flow from Ops: $12M Free cash flow (3) : $8M Outstanding debt: $114M Home Health SS Medicare Admissions: +4% SS Non-Medicare Admissions: +10% Medicare recert rate (2) : 37% Cost per visit: +1% Hospice SS Admissions: +19% SS ADC: +22% Cost per day: (2.2%) Balance Sheet Capital Deployment Cash balance: $8M Net debt: $106M Leverage ratio:1.0x (net) Closed Associated Home Care ($28M) on 3/1 Repurchased 324K shares: $12.3M Adjusted Financial Results $ in Millions, except EPS 1Q15 1Q16 Home Health 241.4 272.7 Hospice 60.2 73.0 Personal Care - 3.1 Total Revenue $ 301.6 $ 348.8 Gross Margin % 43.3% 42.1% Adjusted EBITDA 26.4 23.9 8.7% 6.9% Adjusted EPS $0.30 $0.33 2

Amedisys Strategy: Four Areas of Focus Updated 1Q 2016 Outstanding Outcomes for Our Patients In Their Homes Amedisys Care Centers & Clinical Teams Current: 1Q16 same store Medicare admissions growth of 4% 1Q16 same store hospice admissions growth 19% 13 active M&A processes representing ~$75M in EBITDA Medicare: 76% of revenue Future: Continued HH Medicare and Hospice Growth, strong cash generation, and inorganic opportunities Current: 225 centers currently on HomeCare HomeBase including all Hospice centers All centers will be live on HCHB Nov 1, 2016 Rollout progress easier Phase out of AMS3 in 6/16 Future: Realize $40M - $50M in savings from IT and HCHB efficiencies by end of 2017 Current: 1Q16 TTM full-time employee turnover was 18.8% flat from 2015 and down from 2014 of 21.1% Reduction of inactive PRN s Future: Productivity increase to 29.7 visits per week Improved employee engagement and retention Turnover rate <25% by end of 4Q 2016 Current: Patient Survey score: 3.90 and Quality of Patient care score: 3.50 based on April data 1Q16 32% of centers at 4.0+ STARs VBP states higher than AMED average STAR scores Hospice focus on quality Future: Goal: All HH care centers at 4.0+ STARs at end of 2017 Top of Hospice quality measures 3

Amedisys 1Q 2016 Report Card Category Grade Comments Growth Quality Mix HCHB Installation M&A Pipeline BD Reorg (new) Strong organic volume growth quarter by quarter in home health and hospice. Good progress on STARS and VBP. Analytics in place to drive numbers real time, moving clinical organization to regions to better problem solve. Hospice quality just starting. Building tracking tools. Improving home health revenue mix (76/24 Medicare/Non-Medicare). Improving back office, particularly billing and collections, of managed care business. Strong adoption in regions. Rollout efficiency improving. Learning to control issues that arise with each rollout. Good pipeline but tough landscape; many deals overpriced. Focus on tuck-ins in across business segments. Large hospice valuations are steep. Focus on proactive sourcing; auctions hard work. Focus on reallocating sales / BD efforts. Objective is less reps and more growth. Very early stages. Turnover G&A Segmented employees: Full-Time stable, early stages for PRN s and weekend employees program being developed to utilize them more efficiently. Continued elevated G&A for 1Q 2016 and 2Q 2016 supporting faster volume growth and IT transformation. Back to normal by end of 2016, post-hchb rollout in November. A/R Build Anticipated spike as HCHB rollout volume increases. Expect normal rate of collections by end of 2Q 2016. CJR (new) TBD 7 hospital partnerships and 50 targets identified currently. Early stages and payment mechanisms / economics still shaking out. 4

Driving Growth: Organic and Inorganic Home Health Medicare Completed Episodes Hospice Average Daily Census 80,000 6,000 5,576 5,507 72,032 5,346 67,702 67,288 68,926 4,944 65,311 4,542 60,000 1Q15 2Q15 3Q15 4Q15 *1Q16 * Includes 3,792 completed episodes from Infinity 4,000 1Q15 2Q15 3Q15 4Q15 1Q16 Inorganic Growth Opportunities 80% Medicare Percentage of Revenue Home Health 234 Opportunities Prospected 78% 78% 45 Opportunities Under Review 76% 76% 75% 74% 76% 13 Active Processes 74% 72% 1Q15 2Q15 3Q15 4Q15 1Q16 Representing ~$75M in EBITDA 5

Operational Excellence: HCHB Implementation Timeline We have accelerated our HCHB implementation timeline with a target completion date of November 1, 2016, seven months ahead of our original plan. We are currently at 225 Installs including Infinity. Care Centers 450 400 350 300 250 200 150 Hospice Complete 115* 210 Amedisys Installs and 15 Infinity care centers 99 82 31 411 100 84 50 0 2015 Q1 2016 Q2 2016 Q3 2016 Q4 2016 Total by Jan 1 What s Going Well Challenges Clinician adoption to new workflow Care Center leadership optimizing system quicker than anticipated Support teams have deep understanding of system Increasing improvement in roll-outs Identifying and minimizing initial 60 day disruption at a care center level maintain back office focus (A/R and Clinical recerts) and working capital required before A/R days back to normal Mitigation plans in place and additional pre and post installation training, road shows, coaching meetings being provided to help drive understanding and efficiencies Note: Since rollout started, 1 Hospice and 1 Home Health center closed *Includes 15 Infinity Care Centers 6

Operational Excellence: Roadmap to EBITDA Improvement IT and HCHB Efficiencies and Disruption $14.0 $9.0 ~$12M in savings by 4Q 17 Annualized impact ~$46M $4.0 $(1.0) 1Q 16 2Q 16 3Q 16 4Q 16 1Q 27 2Q 17 3Q 17 4Q 17 Disruption Efficiencies 7

Becoming Employer of Choice: Improving Return on Human Capital 35.0% Voluntary Turnover Clinician Visits per Week 32.2% 30.0 11% 14% 30.0% 27.8% 28.7% 29.0 10% 12% 23% 25% 15% 12% 25.0% 20.0% 21.1% 27.7% 18.8% 18.8% 28.0 27.0 26.0 56% 27.0 28.2 23% 50% 29.7 15.0% 2014 2015 1Q2016 Total Voluntary Turnover Full-Time Voluntary Turnover Total Voluntary Turnover up slightly from 2015 due to enterprise wide focus on terming inactive PRNs 593 PRNs termed in 1Q 2016 of which 221 were inactive / unproductive 1Q 2016Total Voluntary Turnover without unproductive PRN turnover ~27.7% Full-Time Voluntary Turnover flat from 2015 Full time clinicians perform ~83% of visits Excluding inactive PRN terminations Full-Time Voluntary Turnover Goal: 16% by end of 2017 25.0 2015 1Q16 Year End Goal 2017 19% Visits per Week Percentage of Nursing Visits and Turnover 100% 83% 69% 50% 0% 5% 30% 10% 2% 35% Full Time Part Time PRN Weekends Percentage of Visits Percentage Turnover 8

Clinical Distinction: STARs and Value Based Purchasing Quality of Patient Care and Patient Survey Results Metric Release Amedisys Average* Quality of Patient Care Industry Average April 2016 3.50 3.25 Patient Survey April 2016 3.90 3.64 Value Based Purchasing Entities at 4+ Stars: 32% Internal goal of all care centers 4+ Stars by YE 2017 Amedisys performance and improvement in QPC outpaces industry average (improvement from Jan Apr 0.39% vs. industry decline of -0.05%) Amedisys outperforms industry average and most competitors in Patient Survey measures July 2016 QPC Preview Score is 3.59 VBP Opportunity (2015 Revenue in Pilot States: ~$237M) Year + / - Quality % $ s at risk or reward (based on 2015 revenue) 2018 3% ~$7M 2019 5% ~$12M 2020 6% ~$14M 2021 7% ~$17M 2022 8% ~$19M STAR Scores in VBP States Only Quality of Patient Care Patient Satisfaction Industry Industry AMED Avg. AMED Avg. VBP State Avg. 3.60 3.41 3.92 3.63 Currently, only 4 care centers are below 3 STARS, down from 10 at the beginning of 2016 0 centers below 3 STARS by YE 2016 Of the 24 VBP measures, 8 are direct STAR measures which we can use as a proxy for VBP performance Amedisys QPC and PS scores within VBP states are 3.60 and 3.92 respectively, both higher than industry average and in line with overall Amedisys scores Threshold movement to Patient Survey measures dropped the average of all rated providers nationwide from 4.03 to 3.64 Hospice quality ratings starting to formulate *Provider number data 9

Appendix 10

Home Health and Hospice Segment (Adjusted) 1Q 2016 (1) Home Health $ in Millions 1Q15 1Q16 Medicare 187.3 206.8 Non-Medicare - Episodic 54.1 65.9 Revenue $241.4 $272.7 Hospice $ in Millions 1Q15 1Q16 Medicare 56.5 68.7 Non-Medicare 3.7 4.3 Revenue $60.2 $73.0 Gross Margin % 42.5% 41.0% Segment EBITDA 37.4 38.2 15.5% 14.0% Operating Statistics Medicare admit growth - same store 3% 4% Medicare recertification rate 37% *36% Medicare admits 45,351 50,418 Medicare recertifications 24,359 26,023 Non-Medicare admit growth - same store 17% 10% Non-Medicare admits 23,149 25,567 Cost per visit $86 $87 Gross Margin % 46.3% 46.8% Segment EBITDA 13.1 16.6 21.7% 22.7% Operating Statistics Admit growth - same store 7% 19% ADC growth - same store 1% 22% Admits 4,564 5,430 ADC 4,542 5,507 Revenue per day $147 $146 Cost per day $79 $77 Home Health Highlights Organic growth continuing in Medicare admissions; revenue mix improving (76% Medicare) +2% vs 4Q 2015 Non-Medicare continues to decline 24% of revenue in 1Q 2016 vs 26% of revenue in 4Q 2015 *Recert rate drop due in large part to Infinity inclusion in 1Q results Hospice Highlights Fourth straight quarter of double digit same store admissions growth Revenue per day slightly impacted by change in reimbursement; cost per day y/y comparison continued to benefit from drop in pharmacy costs beginning in 2Q15 11

General & Administrative Expenses Adjusted (1,4) $ in Millions, except EPS 1Q15 2Q15 3Q15 4Q15 1Q16 $ in Millions, except EPS 1Q15 2Q15 3Q15 4Q15 1Q16 Corporate Expense Detail Home Health Segment 62.7 62.6 65.7 66.0 65.5 Salary and Benefits 16.3 16.2 15.8 15.8 15.3 Outsourced Services (IT, HR) 0.2 0.4 1.9 4.2 3.7 Acquistions - Infinity 4.9 Other 8.2 9.3 9.0 9.5 9.5 Subtotal 24.7 25.9 26.7 29.5 28.6 Home Health Segment - Total 62.7 62.6 65.7 66.0 70.4 % of Home Health Revenue 26.0% 25.3% 25.9% 25.1% 25.8% HCHB Maint. & Hosting Fees - 1.2 1.7 1.4 1.2 Acquisitions (Infinity/AHC) - - - - 2.1 Hospice Segment 14.4 15.3 16.1 17.0 16.9 Total 24.7 27.1 28.4 30.9 31.9 % of Hospice Revenue 23.9% 23.1% 22.0% 22.4% 23.1% Personal Care Segment - AHC 0.4 % of Personal Care Revenue 12.7% Corporate Admin Spend ($M) ILLUSTRATIVE Corporate 24.7 27.1 28.4 30.9 31.9 % of Total Revenue 8.2% 8.6% 8.7% 9.1% 9.1% Total 101.8 105.0 110.2 113.9 119.6 % of Total Revenue 33.7% 33.4% 33.8% 33.6% 34.3% $24.7 $25.9 $26.7 $29.5 $28.6 1Q15 2Q15 3Q15 4Q15 1Q16 2Q16 3Q16 4Q16 Highlights G&A in business segments as a percentage of revenue relatively constant over the time period Corporate G&A cost increases driven by increase in outsourced services and HCHB maintenance costs that will be reduced and allocated out to the segments once rollout is complete Cost savings plan details IT G&A run-rate improvement of $2.0M by 4Q16 and additional $3.2M by 4Q17 1Q16 should represent highest level of corporate G&A spend during HCHB transition 12

Debt and Liquidity Metrics As of: Outstanding Debt 03/31/16 Term Loan 98.8 Outstanding Revolver 15.0 Total Debt Outstanding 113.8 Less: Deferred Finance Fees (3.2) Total Debt - Balance Sheet 110.6 Total Debt Outstanding 113.8 Less: Cash (7.8) Net Debt 106.0 Leverage Ratio (net) (5) 1.0x As of: $300M Credit Facility 03/31/16 Revolver Size 200.0 Oustanding Revolver 15.0 Letters of Credit 24.7 Available Revolver 160.3 Plus: Cash 7.8 Total Liquidity (6) 168.1 13

Adjusted EBITDA to Free Cash Flow Reconciliation (1,3) S in Millions 1Q15 2Q15 3Q15 4Q15 1Q16 GAAP Net Income (35.0) 10.6 8.4 12.9 6.2 Taxes (21.6) 7.6 6.5 9.6 4.4 Interest 2.4 2.4 4.9 1.0 1.1 Depreciation and amortization 6.5 4.6 4.6 4.2 4.5 Adjustments 74.0 6.4 1.9 (0.1) 7.8 Adjusted EBITDA 26.4 31.7 26.4 27.6 23.9 Provision for doubtful accounts 3.0 2.8 3.6 4.7 3.9 Non-cash compensation, includes 401(k) match expense 4.2 3.8 4.2 5.7 4.1 Cash taxes - (0.4) (0.1) (0.9) - Cash interest (1.8) (1.8) (2.0) (0.6) (0.6) Other (1.8) (6.3) (2.7) (3.9) (9.2) 30.0 29.8 29.4 32.6 22.1 Changes in working capital (15.5) 12.8 1.3 (12.6) (9.9) Cash Flow from Operations 14.5 42.6 30.7 20.0 12.2 Capital Expenditures - Routine (2.1) (4.1) (0.6) (2.6) (3.1) Required debt repayments (3.0) (3.0) - - (1.3) Free cash flow 9.4 35.5 30.1 17.4 7.8 14

Income Statement Adjustments (1) Income Statement $000s Line Item 1Q15 2Q15 3Q15 4Q15 1Q16 Reduction of cost report reserve Revenue (1,059) G&A Acquisition costs G&A, Salary and benefits 502 Exit and restructuring activity G&A, Salary and benefits 3,323 230 1,149 Exit and restructuring activity G&A, Non-cash compensation (644) (174) Exit and restructuring activity G&A, Other 1,061 HCHB implementation G&A, Other 2,048 2,383 2,440 Acquisition costs G&A, Other 1,046 1,202 Legal fees - non-routine G&A, Other 2,121 8,000 286 2,824 1,517 Other Items Asset impairment Asset impairment 75,193 2,075 Debt refinance costs Interest expense 3,212 Legal settlements Other, Miscellaneous, net (818) (307) (1,014) (5,314) (541) Miscellaneous, other (income) expense, net Other, Miscellaneous, net (2,456) (3,945) (1,563) 436 Total 74,040 6,427 5,100 (120) 7,766 EPS Impact $1.37 $0.12 $0.09 $0.02 $0.14 15

Endnotes 1. The financial results for the three-month periods ended March 31, 2015, June 30, 2015, September 30, 2015, December 31, 2015 and March 31, 2016 are adjusted for certain items and should be considered a non-gaap financial measure. A reconciliation of these non- GAAP financial measures is included in the corresponding 8-K detailing quarterly results for each respective reporting period. 2. Recert rate excludes contribution from Infinity HomeCare acquisition. 3. Free cash flow defined as cash flow from operations less routine capital expenditures and required debt repayments. 4. Adjusted G&A expenses do not include bad debt expense or depreciation and amortization 5. Net debt defined as total debt outstanding on credit facility ($114M) less cash balance ($8M). Leverage ratio (net) is defined as net debt divided by last twelve months adjusted EBITDA ($110M). 6. Liquidity defined as the sum of cash balance and available revolving line of credit. 16