UniCredit German Investment Conference. Building growth momentum. Dr. Alexander Rosar Head of Investor Relations. 2011, September 29, Munich

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1 UniCredit German Investment Conference Building growth momentum Dr. Alexander Rosar Head of Investor Relations 2011, September 29, Munich

2 Disclaimer This presentation may contain forward-looking statements based on current assumptions and forecasts made by Bayer Group or subgroup management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer s public reports which are available on the Bayer website at The company assumes no liability whatsoever to update these forwardlooking statements or to conform them to future events or developments.

3 1 st Half 2011 Bayer Continues Positive Momentum 1H 11 % million Sales 18, (+8) EBITDA - reported 3, adjusted 4, EBIT - reported 2, adjusted 3, Net income 1, Net cash flow 2, Free operating cash flow 1, EPS - reported core Highlights Business expansion mainly driven by CropScience and MaterialScience All subgroups contributed to adj. EBITDA improvement, CropScience with strongest y-o-y growth (+33%) Reported EBIT impacted by net special charges of 586m, due to restructuring and litigation 2011 Group financial outlook raised end of Q1 on expected improvement at CropScience ( ) = Fx & portfolio adjusted Page 3 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Group Outlook Raised End Q1 On Expected Improvement at CropScience Sales Fx and portfolio adjusted, EBITDA pre-special items E Original 2011E Actual 1 Sales (Fx & portf. adjusted) 35.1bn +8% 4-6% 35-36bn 5-7% to 36-37bn adj. EBITDA 7.1bn +10% Improve toward 7.5bn > 7.5bn Core EPS % ~10% 15% 1 As published with Q2 stockholder s newsletter Page 4 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Outlook depends on specific planning assumptions as detailed in the Annual/ Quarterly Report

4 Building a World-Class Innovation Company Page 5 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Building A World-Class Innovation Company Portfolio Growth Productivity Build on leading industry position in all 3 subgroups Enhance competitive position Invest in innovation capabilities Maximize value of new product pipeline strength Realize emerging market opportunity Decomplex structures and processes Implement two-year group restructuring plan Target is to deliver mid-single digit organic sales growth in 2011 and to invest 15bn in growth during Page 6 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

5 Bayer A Leader in Its Markets 16.9bn HealthCare Pharmaceuticals 10.9bn, leading positions in key categories 50% 20% Consumer Health 6.0bn, OTC pharmaceuticals, blood glucose meters and veterinary medicines, global #2-4 30% 6.8bn 10.2bn CropScience Agrochemicals and seeds & traits, global #2 in agrochemicals MaterialScience Polyurethanes and polycarbonates, global #1/2 Sales 2010: 35.1bn Break-down excluding reconciliation Page 7 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 New Product Pipeline Strength Page 8 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

6 Promising Late-Stage Pharma Pipeline What it does Status Cardiology Xarelto Riociguat inhibits blood clot formation lowers blood pressure in the lung 1st indication launched, filed; phase III phase III Nexavar inhibits enzymes important for tumor growth launched, additional indications in phase II/III Oncology Regorafenib Alpharadin inhibits enzymes important for tumor growth targeted treatment of bone metastases in prostate cancer phase III Alsympca trial (phase III) stopped early on success Eye Diseases VEGF Trap-Eye inhibits formation of new blood vessels 1st indication filed; phase III Page 9 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Xarelto Novel Direct Factor Xa Inhibitor Large global program involving over 75,000 patients Met or exceeded primary efficacy endpoints in 8 phase III studies: RECORD 1-4, EINSTEIN DVT and EINSTEIN Extension; Rocket AF; MAGELLAN Marketing & regulatory status: Launched in >85 countries for VTE prevention following total knee / hip replacement surgery Filed for stroke prevention in patients with atrial fibrillation (SPAF) in all major regions Positive FDA AdCom vote on approvability in SPAF European Committee (CHMP) recommends approval in SPAF and DVT treatment Two additional phase III programs in chronic indications ongoing ATLAS TIMI51 data expected end 2011/early 2012 EINSTEIN PE data expected end 2011/early 2012 Page 10 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 DVT: deep vein thrombosis VTE: venous thromboembolism

7 VEGF Trap-Eye Fusion Protein To Combat Eye Diseases In-licensed from Regeneron Bayer has exclusive marketing rights ex-us Met primary efficacy endpoint in 4 phase III studies (VIEW I & II, Copernicus & Galileo) Submitted for marketing approval to European and Japanese health authorities for wet age related macular degeneration 1 Filing for central retinal vein occlusion planned for 2012 Additional studies in diabetic macular edema and myopic choroidal neovascularization ongoing 1 US submission (February 2011) by Regeneron Page 11 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Alpharadin New Opportunity to Treat Bone Metastases Alpha-pharmaceutical (based on 223Radium, delivering highly energetic, short ranging radiation) - in-licensed from Algeta Radium as natural bone seeker targeting bone metastases ALSYMPCA (phase III) in patients with bone metastases in prostate cancer (HRPC) stopped early - Alpharadin demonstrated 44% improvement in overall survival Filing targeted mid 2012 Fast track status granted by FDA Tumor cells Newly formed bone Bone metastases Radium-223 deposition Radium-223: highly localized tumor cell killing Page 12 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 HRPC: symptomatic hormone-refractory prostate cancer

8 CropScience Innovation Leadership R&D spending in million > Best-in-class R&D pipeline 23 new agrochemical active ingredients launched since 2000, generated sales of 2bn in 2009 Launched >45 AgChem formulations and >170 seed varieties since 2010 Planning to launch 4 new molecules between 2012 and 2015 Refocus R&D: BioScience investment significantly increased e AgChem BioScience Page 13 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 MaterialScience World-Class Applications Research Bayseal Creates a seamless air barrier system working like a building envelope Baytherm Combines high mechanical strength with high insulating capacity and low weight DurFlex Improving noise reduction and economics of rail track operations Bayblend FR A new safety concept for car batteries to make housings flame retardant Makrolon Forming lightweight exterior car body parts from polycarbonate Bayfol Reflex Actuators out of polymers give tactile feedback precisely adjusted to requirements Makrofol ID Film for ID cards providing scratch resistance and protecting against counterfeit Baycusan Solvent-free polyurethane based polymers for cosmetic applications Page 14 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

9 Opportunity Emerging Markets Page 15 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, st Half 2011 Emerging Markets Leading The Growth 1 st Half 2011 Group sales by region USA +5% 20% 19% 36% 34% Emerging Economies¹ +11% Emerging Economies +9% ~2,500 +9% ~1,800 35% 12% +17% ~1, % ~900 Western Europe +7% Others² +5% Group 18,667m; +8% Emerging Asia³ Latin America Eastern Europe Africa & Middle East In million, % yoy Fx adjusted Page 16 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 ¹ Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe ² Others = Japan, Australia, New Zealand, Canada ³ Emerging Asia = Asia w/o Japan, Australia, New Zealand

10 All BRIC-Countries in Our Most Important Country Portfolio Salesin bn % % yoy Fx adjusted Sales by country full year % +30% % % -5% +6% % +5% +1% +5% +3% +23% +12% * Page 17 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 *Greater China includes PR China, Hongkong, Macau and Taiwan Bayer is One of The Leading International HealthCare Companies in China Sales in million; % y-o-y Fx adjusted HealthCare 1H m +31% y-o-y (Fx-adj.)* Strong growth Driven by Pharmaceuticals (+35% yoy) 1,000 sales representatives to be added through 2011 Top products growth in 1H 2011* Aspirin Cardio Adalat Avelox Glucobay Ultravist +64% +41% +35% +28% +20% Significant investment commitment Approx. 5,300 employees (2010) 100m over 5 years to set-up a global R&D center in China Beijing manufacturing site expansion (~ 45m through 2015) Partnership with Tsinghua University (joint drug discovery, student support) * People s Republic of China Page 18 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

11 1bn New Investment Plan at MaterialScience in China China s importance further growing China already is the world s largest PCS market China is set to become the world s largest PUR market by 2015 Commitment to growth in China 2.1bn investment program in integrated polymer site in Shanghai, China until 2012 New investment of approx. 1bn in Shanghai by 2016 to Increase MDI capacity to 1,000kt/year More than double PCS capacity to 500kt/year Increase HDI capacity, new 50kt/year line planned Transfer of PCS Headquarters from Leverkusen to Shanghai Increasing downstream presence (investment of 110m by 2012) PCS = Polycarbonates PUR = Polyurethanes Page 19 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 CropScience in Brazil Gained Share in One of the World s Largest Ag Markets Brazil is the 2nd largest market for CropScience Bayer is one of the leading suppliers and growing strongly Bayer gained market share in each of the past 3 years CropScience sales (in m) Risk management systems in place to limit the potential impact of reduced credit availability; established barter business CAGR +19% Page 20 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

12 More Innovation Less Administration Page 21 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Restructuring Program Initiated Contribution by Subgroup Savings Initiative Holding & Admin. ~12% ~34% CropScience HealthCare ~54% Savings and efficiency initiative at HealthCare, CropScience and corporate level Annual cost savings of 800m starting 2013, reinvestment of ~50% One-time-charges of around 1bn by end of 2012 Plans include reductions of 4,500 people 2,500 new hires in growth and innovation, particularly in emerging markets Page 22 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

13 Summary Bayer continued positive business momentum during 1HY 2011 Group full year 2011 outlook projects 5 to 7% organic sales growth and adj. EBITDA above 7.5bn Innovation pipeline will build growth momentum Significant emerging markets opportunity Two-year group restructuring plan to free-up resources Page 23 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011 Reporting Events and AGM Date Event Publication Thursday, October 27, 2011 November 16-18, 2011 Tuesday, February 28, 2012 Thursday, April 26, 2012 Friday, April 27, 2012 Tuesday, July 31, 2012 Tuesday, October 30, 2012 Investor Conference Call China Conference 2011, Shanghai Investor Conference Call Investor Conference Call Annual General Meeting Investor Conference Call Investor Conference Call 3 rd Quarter 2011 Results Stockholders Newsletter 2011 Annual Report 1 st Quarter 2012 Results Stockholders Newsletter 2 nd Quarter 2012 Results Stockholders Newsletter 3 rd Quarter 2012 Results Stockholders Newsletter Page 24 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

14 Investor Relations Contacts Dr. Alexander Rosar Head of Investor Relations Phone: Dr. Jürgen Beunink Phone: Peter Dahlhoff Phone: Fabian Klingen Phone: Ute Menke Phone: Judith Nestmann Phone: Dr. Olaf Weber Phone: Page 25 Bayer Investor Presentation UniCredit Conference Alexander Rosar Sep 29, 2011

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